3. 脊髄性筋萎縮症 Spinal muscular atrophy Clinical trials / Disease details

臨床試験数 : 237 / 薬物数 : 123 - (DrugBank : 29) / 標的遺伝子数 : 51 - 標的パスウェイ数 : 75

9 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JMA-IIA00259	16/08/2016	10/08/2016	Multicenter cooperative and investigator initiated clinical trial using valproic acidin childhood on ...	Multicenter cooperative and investigator initiated clinical trial using valproic acidin childhood on ...	spinal muscular atrophy	Intervention type:DRUG. Intervention1:SMART, Dose form:GRANULES, Route of administration:ORAL, inten ...	Institute of Medical Genetics, Tokyo Women's Medical University	NULL	Recruiting	>=1 YEARS	<8 YEARS	BOTH	28	Phase 2B	Japan
2	JPRN-JMA-IIA00231	29/01/2016	01/12/2015	Multicenter cooperative and investigator initiated clinical trial using valproic acidin childhood on ...	Multicenter cooperative and investigator initiated clinical trial using valproic acidin childhood on ...	spinal muscular atrophy	Intervention type:DRUG. Intervention1:SMART, Dose form:GRANULES, Route of administration:ORAL, inten ...	Institute of Medical Genetics, Tokyo Women's Medical University	NULL	Completed	>=1 YEARS	<7 YEARS	BOTH	28	Phase 2B	Japan
3	JPRN-JMA-IIA00190	22/07/2014	01/08/2014	Multicenter cooperative and investigator initiated clinical trial using valproic acidin childhood on ...	Multicenter cooperative and investigator initiated clinical trial using valproic acidin childhood on ...	spinal muscular atrophy	Intervention type:DRUG. Intervention1:SMART, Dose form:GRANULES, Route of administration:ORAL, inten ...	Institute of Medical Genetics, Tokyo Women's Medical University	NULL	Completed	No Limit	<8 YEARS	BOTH	13	Phase 2A	Japan
4	NCT01671384 (ClinicalTrials.gov)	August 2013	13/8/2012	Valproate and Levocarnitine in Children With Spinal Muscular Atrophy	Randomized Placebo Controlled Trial of Valproateand Levocarnitine in Children With Spinal Muscular A ...	Spinal Muscular Atrophy	Drug: Valproate , Levocarnitine;Drug: Placebo	All India Institute of Medical Sciences, New Delhi	NULL	Recruiting	2 Years	15 Years	Both	60	Phase 3	India
5	EUCTR2008-003915-11-DE (EUCTR)	24/09/2009	25/06/2009	Phase I/II Trial of Valproic Acidand Carnitine in Infants with Spinal Muscular Atrophy Type I (CARNI ...	Phase I/II Trial of Valproic Acidand Carnitine in Infants with Spinal Muscular Atrophy Type I (CARNI ...	Spinal Muscular Atrophy Type I in infants MedDRA version: 9.1;Level: LLT;Classification code 1005120 ...	Trade Name: Orfiril Saft INN or Proposed INN: VALPROATE SODIUM Trade Name: Biocarn INN or Proposed INN: ...	University of Utah	NULL	Not Recruiting			Female: yes Male: yes	36	Phase 1/2	Germany
6	NCT00661453 (ClinicalTrials.gov)	April 2008	14/4/2008	CARNIVAL Type I: Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy (SMA) Type I	Phase I/II Trial of Valproic Acidand Carnitine in Infants With Spinal Muscular Atrophy Type I (CARNI ...	Spinal Muscular Atrophy Type I	Drug: Valproic Acid and Levocarnitine	University of Utah	Families of Spinal Muscular Atrophy;Leadiant Biosciences, Inc.	Completed	N/A	12 Months	All	40	Phase 1/Phase 2	United States;Canada;Germany
7	NCT00481013 (ClinicalTrials.gov)	July 2007	30/5/2007	Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy	Prospective Controlled Trial of Valproic Acidin Ambulant Adults With Spinal Muscular Atrophy (VALIAN ...	Spinal Muscular Atrophy	Drug: Valproic Acid (VPA);Drug: Placebo	University of Utah	Families of Spinal Muscular Atrophy;Abbott	Completed	18 Years	60 Years	Both	33	Phase 2	United States
8	NCT00227266 (ClinicalTrials.gov)	September 2005	23/9/2005	Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy	Multi-center Phase II Trial of Valproic Acidand Carnitine in Patients With Spinal Muscular Atrophy ( ...	Spinal Muscular Atrophy	Drug: Valproic Acid and Levocarnitine;Drug: Placebo	University of Utah	Families of Spinal Muscular Atrophy;Leadiant Biosciences, Inc.;Abbott	Completed	2 Years	17 Years	All	94	Phase 2	United States;Canada
9	NCT00374075 (ClinicalTrials.gov)	September 2003	6/9/2006	Study of Safety and Dosing Effect on SMN Levels of Valproic Acid(VPA) in Patients With Spinal Muscul ...	In Vivo Study of Safety, Tolerability and Dosing Effect on SMN mRNA and Protein Levels of Valproic A ...	Spinal Muscular Atrophy	Drug: Valproic Acid	University of Utah	Families of Spinal Muscular Atrophy;Sigma Tau Pharmaceuticals, Inc.;Abbott	Completed	2 Years	N/A	Both	42	Phase 1	United States

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