42. 結節性多発動脈炎 Polyarteritis nodosa Clinical trials / Disease details

臨床試験数 : 15 / 薬物数 : 26 - (DrugBank : 16) / 標的遺伝子数 : 26 - 標的パスウェイ数 : 105

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05168475 (ClinicalTrials.gov)	July 14, 2021	9/12/2021	Biologics in Refractory Vasculitis	Biologics in Refractory Vasculitis (BIOVAS): A Pragmatic, Randomised, Double-blind, Placebo-controll ...	Giant Cell Arteritis;Takayasu Arteritis;Cogan Syndrome;Relapsing Polychondritis;Cryoglobulinemic Vas ...	Biological: Rituximab;Biological: Infliximab;Biological: Tocilizumab	Cambridge University Hospitals NHS Foundation Trust	NULL	Recruiting	5 Years	N/A	All	140	Phase 2	United Kingdom
2	EUCTR2019-003964-30-GB (EUCTR)	22/10/2020	31/07/2020	Biologics in refractory vasculitis (BIOVAS): A pragmatic, randomised, double-blind, placebo-controll ...	Biologics in refractory vasculitis (BIOVAS): A pragmatic, randomised, double-blind, placebo-controll ...	Non-ANCA associated vasculitides: 1.Giant cell arteritis (GCA)2.Takayasu’s arteritis (TA)3.Polyarter ...	Product Name: Infliximab Product Code: N/A INN or Proposed INN: Infliximab Trade Name: Rituximab Product ...	Cambridge University Hospitals NHS Foundation Trust	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 2	United Kingdom
3	NCT03482479 (ClinicalTrials.gov)	February 4, 2019	22/3/2018	Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis	Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis	Eosinophilic Granulomatosis With Polyangiitis (EGPA);Churg-Strauss Syndrome (CSS);Giant Cell Arterit ...	Drug: Naltrexone Hydrochloride;Other: Placebo Comparator	University of Pennsylvania	NULL	Recruiting	18 Years	N/A	All	36	Phase 2	United States
4	NCT02939573 (ClinicalTrials.gov)	January 1, 2017	18/10/2016	A Randomized Multicenter Study for Isolated Skin Vasculitis	A Randomized Multicenter Study for Isolated Skin Vasculitis	Primary Cutaneous Vasculitis;Cutaneous Polyarteritis Nodosa;IgA Vasculitis;Henoch-Schönlein Purpura	Drug: Colchicine;Drug: Dapsone;Drug: Azathioprine	University of Pennsylvania	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS);National Center for Ad ...	Recruiting	18 Years	N/A	All	90	Phase 2	United States;Canada;Japan
5	EUCTR2013-004668-71-ES (EUCTR)	13/10/2016	05/08/2016	A study of treatment for polyarteritis nodosa in children	An Open Label Randomised Controlled Trial of Mycophenolate Mofetil Versus Cyclophosphamide for the I ...	Childhood systemic polyarteritis nodosa(PAN) MedDRA version: 19.0;Level: LLT;Classification code 100 ...	Trade Name: CellCept Product Name: CellCept (Mycophenolate Mofetil) INN or Proposed INN: Mycophenolate m ...	University College London	NULL	Not Recruiting			Female: yes Male: yes	40	Phase 3	Portugal;Slovenia;Greece;Spain;Turkey;United Kingdom;Italy;Czech Republic;Belgium;Poland;Croatia;Ger ...
6	EUCTR2013-004668-71-IT (EUCTR)	01/08/2016	14/07/2015	An Open Label Randomised Controlled Trial of Mycophenolate Mofetil Versus Cyclophosphamide for the I ...	An Open Label Randomised Controlled Trial of Mycophenolate Mofetil Versus Cyclophosphamide for the I ...	Childhood systemic polyarteritis nodosa(PAN) MedDRA version: 19.0;Level: LLT;Classification code 100 ...	Trade Name: CellCept Product Name: CellCept (Mycophenolate Mofetil) INN or Proposed INN: Mycophenolate m ...	University College London	NULL	Not Recruiting			Female: yes Male: yes	40	Phase 3	Portugal;Slovenia;Greece;Spain;Turkey;United Kingdom;Italy;Czech Republic;Belgium;Poland;Croatia;Ger ...
7	EUCTR2013-004668-71-GB (EUCTR)	25/09/2014	25/09/2014	A study of treatment for polyarteritis nodosa in children	An Open Label Randomised Controlled Trial of Mycophenolate Mofetil Versus Cyclophosphamide for the I ...	Childhood systemic polyarteritis nodosa(PAN) MedDRA version: 17.0;Level: LLT;Classification code 100 ...	Trade Name: CellCept Product Name: CellCept (Mycophenolate Mofetil) INN or Proposed INN: Mycophenolate m ...	University College London	NULL	Not Recruiting			Female: yes Male: yes	40	Phase 3	Croatia;Portugal;Slovenia;Greece;Spain;Turkey;United Kingdom;Italy;Czech Republic;Belgium;Poland;Ger ...
8	NCT00751517 (ClinicalTrials.gov)	September 2008	11/9/2008	Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides	Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides. ...	Wegener's Granulomatosis;Churg-Strauss Syndrome;Microscopic Polyangiitis;Polyarteritis Nodosa	Drug: Methotrexate;Drug: Cyclophosphamide	University of Parma	NULL	Active, not recruiting	18 Years	80 Years	Both		Phase 2	Italy
9	NCT00647166 (ClinicalTrials.gov)	May 2008	26/3/2008	Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosaor Eosinoph ...	Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nod ...	MPA;PANor EGPA With FFS=0;At Diagnosis or Within the First 15 Days Following Initiation of Corticost ...	Drug: corticosteroid and azathioprine;Drug: corticosteroid and placebo	Assistance Publique - Hôpitaux de Paris	NULL	Completed	18 Years	N/A	Both	114	Phase 3	France
10	NCT00307671 (ClinicalTrials.gov)	July 2005	27/3/2006	Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years	Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies ...	Vasculitis;Wegener's Granulomatosis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Polyarteritis No ...	Drug: prednisone , methylprednisolone,cyclophosphamides;Drug: Cyclophosphamide , Azathioprine,predniso ...	Assistance Publique - Hôpitaux de Paris	NULL	Completed	65 Years	N/A	Both	108	Phase 4	France

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