46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

17 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05626348 (ClinicalTrials.gov)	December 22, 2021	15/11/2022	The Clinical Efficacy of Immunomodulators in RA Patients	The Clinical Study to Observe the Efficacy and Safety of Immunomodulators in Rheumatoid Arthritis Pa ...	Arthritis, Rheumatoid	Drug: Iguratimod;Drug: Methotrexate;Drug: Adalimumab Injection;Drug: Leflunomide;Drug: Hydroxychloroq ...	Qilu Hospital of Shandong University	NULL	Recruiting	18 Years	80 Years	All	400	Phase 4	China
2	ChiCTR2100048699	2021-05-25	2021-07-12	A multicentre, randomized, parallel-controlled clinical study of the efficacy and safety of Iguratim ...	Clinical cohort study of organ injury and repair in severe rheumatic diseases---rheumatoid arthritis ...	Rheumatoid Arthritis	A:Iguratimod combination therapy with JAK inhibitor;B:JAK inhibitor;	Qilu Hospital of Shandong University	NULL	Recruiting	18	65	Both	A:180;B:180;		China
3	ChiCTR2200055876	2020-12-01	2022-01-22	Efficacy and safety of Iguratimodcombined with adalimumab in active rheumatoid arthritis with poor r ...	Efficacy and safety of Iguratimodcombined with adalimumab in active rheumatoid arthritis with poor r ...	Rheumatoid Arthritis	Treatment group:IGU 25mg bid + adalimumab 40mg q2w;	Shandong Provincial Hospital Affiliated to Shandong First Medical University	NULL	Recruiting	18	65	Both	Treatment group:98;	Phase 4	China
4	NCT04928066 (ClinicalTrials.gov)	March 1, 2020	9/6/2021	The Efficacy and Safety of Tofacitinib (TF) With Iguratimod (IGU) on RA	Efficacy and Safety of Tofacitinib (TF) Combined With Iguratimod(IGU) in the Treatment of Moderate t ...	Arthritis, Rheumatoid	Drug: Iguratimod;Drug: Tofacitinib;Drug: Pred	Qilu Hospital of Shandong University	NULL	Recruiting	18 Years	80 Years	All	100	Phase 4	China
5	ChiCTR1900021686	2019-03-15	2019-03-05	A observational study for iguratimodcombined with methotrexate in remission or reversion bone erosio ...	A observational study for iguratimodcombined with methotrexate in remission or reversion bone erosio ...	Rheumatoid arthritis	Case Series:IGU combined with MTX ;	Nanjing Drum Tower Hospital	NULL	Pending	18	70	Both	Case Series:30;	Phase 4	China
6	ChiCTR1800015615	2018-05-01	2018-04-11	Clinical observation of the protective effect of iguratimod on rheumatoid arthritis	Clinical observation of the protective effect of iguratimod on rheumatoid arthritis	Rheumatoid Arthritis	first:MTX;second:MTX in combination with Irammod;third:MTX and LEF;fourth:MTX, LEF and Irammod;	Tianjin First Central Hospital	NULL	Pending	18	75	Both	first:30;second:30;third:30;fourth:30;		China
7	JPRN-UMIN000027719	2017/06/12	12/06/2017	Effect of tapering methotrexate in rheumatoid arthritis patients after add-on iguratimod therapy.	Effect of tapering methotrexate in rheumatoid arthritis patients after add-on iguratimodtherapy. - E ...	rheumatoid arthritis/remission	add-on iguratimod tapering MTX continuing the treatment	Osaka Medical College	NULL	Recruiting	20years-old	100years-old	Male and Female	100	Not selected	Japan
8	NCT03855007 (ClinicalTrials.gov)	January 1, 2016	15/2/2019	The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months Treatment	Prospective Clinical Study to Observe the Efficacy and Safety of Iguratimodin Rheumatoid Arthritis a ...	Arthritis, Rheumatoid	Drug: Iguratimod;Drug: MTX;Drug: HCQ;Drug: Pred	Qilu Hospital of Shandong University	NULL	Active, not recruiting	16 Years	90 Years	All	200	Phase 4	China
9	JPRN-UMIN000020833	2015/10/09	01/02/2016	The efficacy of Iguratimod, and adding Adalimumab in patients with active rheumatoid arthritis: an o ...	The efficacy of Iguratimod, and adding Adalimumab in patients with active rheumatoid arthritis: an o ...	Rheumatoid arthritis	Administer MTX6-16mg/week for 12 weeks to patients with MDA-RA. If patients can't take MTX, administe ...	Zenjinkai Shimin-no-mori Hospital	NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	240	Not selected	Japan
10	NCT02275299 (ClinicalTrials.gov)	September 2013	23/10/2014	Study of IguratimodPlus Methotrexate Compared to Leflunomid Plus Methotrexate in Patients With Rheum ...	A Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Iguratimodor Leflunomide in ...	Rheumatoid Arthritis	Drug: Iguratimod;Drug: Leflunomide;Drug: Methotrexate	Jiangsu Simcere Pharmaceutical Co., Ltd.	NULL	Recruiting	18 Years	70 Years	Both	240	Phase 4	China

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