46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details
臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-UMIN000042632 | 2020/01/01 | 03/12/2020 | THE EFFECT OF LASER THERAPY ON EARLY ONSET RHEUMATOID ARTHRITIS PATIENTS | THE EFFECT OF LASER THERAPY ON EARLY ONSET RHEUMATOID ARTHRITIS PATIENTS - laser effectiveness in rheumatoid arthritis | Rheumatoid arthritis | low level laser therapy. Each patient in group 1 takes 20 sessions of LLLT , in the form of 2 courses, each course contains 10 sessions ,as 3 sessions every week ,10 days free between 2 courses. The laser apparatuses used for therapy in this study were the following, 1.HeNe Laser wavelength 632,8 nm, continuous emission, output power 7.3 mW. 2.GaAIAs diode laser (830 nm, maximum output power 300 mW). 12 patients placebo laser and naproxen Naproxen is given as tablet 500mg twice per day. 12 patients naproxen Naproxen is given as tablet 500mg twice per day. 10 patients | Rheumatology clinic at Al-Kindy Teaching Hospital /Baghdad/Iraq | NULL | Complete: follow-up complete | 20years-old | 80years-old | Male and Female | 34 | Not applicable | Asia(except Japan) |
| 2 | NCT03719469 (ClinicalTrials.gov) | January 20, 2015 | 6/9/2018 | Circulating microRNAs as Novel Prognosis Biomarkers for Rheumatoid Arthritis | Circulating microRNAs Expression as Predictors of Clinical Response in Rheumatoid Arthritis Patients Treated With Green Tea | Rh Disease | Dietary Supplement: Green tea group | King Saud University | NULL | Completed | 18 Years | 85 Years | All | 150 | NULL | |
| 3 | NCT02257047 (ClinicalTrials.gov) | October 2014 | 2/10/2014 | Red Yeast Rice and Subclinical Atherosclerosis in Patients With Rheumatoid Arthritis | Rheumatoid Arthritis | Dietary Supplement: Tea;Dietary Supplement: RYR | Chengdu PLA General Hospital | NULL | Enrolling by invitation | 18 Years | 75 Years | All | 120 | N/A | China | |
| 4 | ChiCTR-TRC-12003871 | 2009-05-01 | 2012-01-01 | Phase II of Tong Luo Hua Shi Capsules in Rheumatoid Arthritis | A Multi-center, Randomized, Double-blind, Phase II Study Evaluating the Safety and Efficacy of Tong Luo Hua Shi Capsules in Participants with Rheumatoid Arthritis | Rheumatoid arthritis | A:2 pieces of Tong Luo Hua Shi Capsules. Votalin and Leflunomide Tablets when necessary;B:3 pieces of Tong Luo Hua Shi Capsules. Votalin and Leflunomide Tablets when necessary;C:4 pieces of Tong Luo Hua Shi Capsules. Votalin and Leflunomide Tablets when necessary;D:4 pieces placebo; | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine | NULL | Completed | 18 | 68 | Both | A:60;B:60;C:60;D:60; | I+2 (Phase 1+Phase 2) | China |
| 5 | JPRN-UMIN000001798 | 2008/07/01 | 25/03/2009 | Prevention of cartilage destruction in rheumatoid arthritis by etanercept (PRECEPT study) | Prevention of cartilage destruction in rheumatoid arthritis by etanercept (PRECEPT study) - PRECEPT study | Rheumatoid arthritis | Injection of etanercept by 50 mg/week for one year Injection of etanercept by 25 mg/week for one year | Team RA, Rheumatosurgery, Osaka City University Medical School | NULL | Complete: follow-up complete | 20years-old | 80years-old | Male and Female | 100 | Not applicable | Japan |
| 6 | ChiCTR-TRC-11001755 | 2007-10-01 | 2011-12-01 | Phase II of Tu Fu Ling Tablets in Rheumatoid Arthritis | A Multi-center, Randomized, Double-blind, Double-dummy, Phase II Study Evaluating the Safety and Efficacy of Tu Fu Ling Tablets in Participants with Rheumatoid Arthritis | Rheumatoid Arthritis | A:Tu Fu Ling Tablets, 200mg Bid. Other: Placebo;B:Tu Fu Ling Tablets, 100mg Tid. Other: Placebo. ;C:Leflunomide Tablets, 20mg Qd. Other: Placebo; | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine | NULL | Completed | 18 | 65 | Both | A:80;B:80;C:80; | 2 (Phase 2 study) | China |
| 7 | EUCTR2004-002006-30-GB (EUCTR) | 17/11/2004 | 17/02/2005 | Triple therapy in early active rheumatoid arthritis - TEAR | Triple therapy in early active rheumatoid arthritis - TEAR | Rheumatoid arthritis | Product Name: Methotrexate INN or Proposed INN: Methotrexate Trade Name: Salazopyrin En-Tabs Product Name: sulfasalazine INN or Proposed INN: Sulfasalazine Trade Name: Plaquenil Product Name: Hydroxychloroquine INN or Proposed INN: Hydroxychloroquine | North Glasgow NHS Trust | NULL | Not Recruiting | Female: yes Male: yes | 96 | United Kingdom | |||
| 8 | NCT00259610 (ClinicalTrials.gov) | May 2004 | 28/11/2005 | Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) | Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) | Rheumatoid Arthritis | Drug: methotrexate;Drug: sulfasalazine;Drug: hydroxychloroquine;Drug: etanercept | University of Alabama at Birmingham | Amgen;Barr Laboratories;Pfizer | Completed | 18 Years | N/A | All | 755 | Phase 4 | United States |