60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details

臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166

49 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05600426 (ClinicalTrials.gov)	January 25, 2023	20/10/2022	A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Ap ...	A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation With Immune Suppr ...	Severe Aplastic Anemia	Drug: cyclosporine;Procedure: Matched Unrelated Donor Hematopoetic Stem Cell Transplant;Drug: horse ...	Boston Children's Hospital	Center for International Blood and Marrow Transplant Research;National Institutes of Health (NIH);Na ...	Recruiting	0 Years	25 Years	All	234	Phase 3	United States
2	NCT05031897 (ClinicalTrials.gov)	October 25, 2021	31/8/2021	Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Und ...	A 2 Step Approach to Haploidentical Transplant Using Radiation-Based Reduced Intensity Conditioning	Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Aplastic Anemia;Chronic Lymphocytic Leukemia;Chr ...	Procedure: Hematopoietic Cell Transplantation;Drug: Mycophenolate Mofetil;Drug: Tacrolimus;Drug: Cycl ...	Thomas Jefferson University	NULL	Recruiting	18 Years	N/A	All	67	Phase 2	United States
3	NCT03622788 (ClinicalTrials.gov)	August 8, 2019	3/8/2018	Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell T ...	Anti-Viral Central Memory CD8 Veto Cells in Haploidentical Hematopoietic Stem Cell Transplantation	Follicular Lymphoma;Hodgkin Lymphoma;Mantle Cell Lymphoma;Myelodysplastic Syndrome;Myeloproliferativ ...	Biological: Anti-Thymocyte Globulin;Drug: Cyclophosphamide;Biological: Cytokine-treated Veto Cells;D ...	M.D. Anderson Cancer Center	NULL	Recruiting	12 Years	75 Years	All	24	Phase 1/Phase 2	United States
4	NCT03821987 (ClinicalTrials.gov)	December 17, 2018	23/1/2019	Risk Stratification Directed Conditioning Regimen for Haploidentical HSCT in SAA	Risk Stratification Directed Conditioning Regimen for Haploidentical HSCT in SAA	Aplastic Anemia;Stem Cell Transplant Complications;Engraft Failure	Drug: Fludarabine	Peking University People's Hospital	NULL	Recruiting	3 Years	55 Years	All	55	N/A	China
5	NCT03579875 (ClinicalTrials.gov)	November 13, 2018	25/5/2018	T Cell Receptor a/ß TCD HCT in Patients With Fanconi Anemia	T Cell Receptor Alpha/Beta T Cell Depleted (a/ß TCD) Hematopoietic Cell Transplantation in Patients ...	Fanconi Anemia;Severe Aplastic Anemia;Myelodysplastic Syndromes	Drug: Total Body Irradiation (TBI) (Plan 1);Drug: Cyclophosphamide (CY) (Plan 1);Drug: Fludarabine (FL ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	65 Years	All	48	Phase 2	United States
6	NCT03531736 (ClinicalTrials.gov)	May 9, 2018	9/5/2018	T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intens ...	Allogeneic Hematopoietic Stem Cell Transplantation of a/ß T-Lymphocyte Depleted Graft Conditioned Wi ...	Myeloid Diseases	Drug: Antithymocyte globulin (Rabbit);Drug: fludarabine;Radiation: total body irradiation;Drug: cycl ...	Memorial Sloan Kettering Cancer Center	NULL	Recruiting	18 Years	N/A	All	15	Phase 1	United States
7	NCT03333486 (ClinicalTrials.gov)	December 7, 2017	2/11/2017	FludarabinePhosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Tr ...	A Phase II Trial of Haploidentical Allogeneic Stem Cell Transplantation Utilizing Mobilized Peripher ...	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;Acute Leukemia in Remission;Acute ...	Drug: Cyclophosphamide;Drug: Fludarabine Phosphate;Other: Laboratory Biomarker Analysis;Procedure: Pe ...	Roswell Park Cancer Institute	NULL	Active, not recruiting	1 Year	75 Years	All	31	Phase 2	United States
8	NCT03192397 (ClinicalTrials.gov)	August 9, 2017	16/6/2017	Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graf ...	A Phase Ib/2 Trial of Fludarabine/Melphalan/Total Body Irradiation With Post Transplant Cyclophospha ...	Acute Myeloid Leukemia in Remission;Adult Acute Lymphoblastic Leukemia in Complete Remission;Chronic ...	Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;Drug: Cyclophosphamide;Drug: Fludarabi ...	Roswell Park Cancer Institute	NULL	Active, not recruiting	18 Years	N/A	All	35	Phase 1/Phase 2	United States
9	NCT02918292 (ClinicalTrials.gov)	July 3, 2017	27/9/2016	Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)	Optimizing Haploidentical Aplastic Anemia Transplantation (CHAMP) (BMT CTN 1502)	Severe Aplastic Anemia	Drug: Antithymocyte Globulin (ATG);Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total Body Ir ...	Medical College of Wisconsin	National Heart, Lung, and Blood Institute (NHLBI);National Cancer Institute (NCI);Blood and Marrow T ...	Completed	N/A	75 Years	All	32	Phase 2	United States
10	NCT02960646 (ClinicalTrials.gov)	January 18, 2017	8/11/2016	Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies	Phase I Clinical Trial Using an Engineered Peripheral Blood Graft for Haploidentical Transplantation ...	Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Acute Myeloid Leukemia Arising From Previous Mye ...	Drug: Cyclophosphamide;Biological: Filgrastim;Drug: Fludarabine Phosphate;Other: Laboratory Biomarker ...	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	Completed	18 Years	65 Years	All	11	Phase 1	United States

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