60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details

臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166

10 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05031897 (ClinicalTrials.gov)	October 25, 2021	31/8/2021	Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Und ...	A 2 Step Approach to Haploidentical Transplant Using Radiation-Based Reduced Intensity Conditioning	Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Aplastic Anemia;Chronic Lymphocytic Leukemia;Chr ...	Procedure: Hematopoietic Cell Transplantation;Drug: Mycophenolate Mofetil;Drug: Tacrolimus;Drug: Cycl ...	Thomas Jefferson University	NULL	Recruiting	18 Years	N/A	All	67	Phase 2	United States
2	NCT03192397 (ClinicalTrials.gov)	August 9, 2017	16/6/2017	Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graf ...	A Phase Ib/2 Trial of Fludarabine/Melphalan/Total Body Irradiation With Post Transplant Cyclophospha ...	Acute Myeloid Leukemia in Remission;Adult Acute Lymphoblastic Leukemia in Complete Remission;Chronic ...	Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;Drug: Cyclophosphamide;Drug: Fludarabi ...	Roswell Park Cancer Institute	NULL	Active, not recruiting	18 Years	N/A	All	35	Phase 1/Phase 2	United States
3	NCT02960646 (ClinicalTrials.gov)	January 18, 2017	8/11/2016	Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies	Phase I Clinical Trial Using an Engineered Peripheral Blood Graft for Haploidentical Transplantation ...	Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Acute Myeloid Leukemia Arising From Previous Mye ...	Drug: Cyclophosphamide;Biological: Filgrastim;Drug: Fludarabine Phosphate;Other: Laboratory Biomarker ...	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	Completed	18 Years	65 Years	All	11	Phase 1	United States
4	NCT01529827 (ClinicalTrials.gov)	February 28, 2012	6/2/2012	Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral B ...	A Phase II Trial of Reduced Intensity Allogeneic Stem Cell Transplantation With Fludarabine, Melphal ...	Accelerated Phase Chronic Myelogenous Leukemia;Adult Acute Lymphoblastic Leukemia in Remission;Adult ...	Drug: fludarabine phosphate;Drug: melphalan;Radiation: total-body irradiation;Drug: tacrolimus;Drug: ...	Roswell Park Cancer Institute	NULL	Completed	3 Years	75 Years	All	94	Phase 2	United States
5	NCT01500161 (ClinicalTrials.gov)	November 2011	18/11/2011	Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic ...	A Phase II Study Of Pooled Unrelated Donor Umbilical Cord Blood (UCB) Transplant For Patients With H ...	Acute Myelogenous Leukemia;Acute Lymphocytic Leukemia;Chronic Lymphocytic Leukemia;Chronic Myelogeno ...	Drug: Busulfan;Drug: Clofarabine;Drug: Fludarabine;Drug: Melphalan;Drug: Carmustine;Drug: Etoposide; ...	Texas Oncology Cancer Center	NULL	Terminated	18 Years	65 Years	Both	1	Phase 2	United States
6	NCT00856388 (ClinicalTrials.gov)	January 14, 2009	4/3/2009	Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Pat ...	A Pilot Trial Of Reduced Intensity Allogeneic Stem Cell Transplantation With Fludarabine, Melphalan, ...	Accelerated Phase Chronic Myelogenous Leukemia;Acute Myeloid Leukemia With Multilineage Dysplasia Fo ...	Drug: fludarabine phosphate;Drug: melphalan;Radiation: total-body irradiation;Procedure: allogeneic h ...	Roswell Park Cancer Institute	National Cancer Institute (NCI)	Completed	3 Years	75 Years	All	62	N/A	United States
7	EUCTR2007-001657-26-GB (EUCTR)	29/02/2008	07/11/2007	Single Centre Phase II Pilot study of Unrelated Cord Blood Transplantation in Patients with Poor Ris ...	Single Centre Phase II Pilot study of Unrelated Cord Blood Transplantation in Patients with Poor Ris ...	1.Acute, chronic leukaemia or myelodysplastic syndrome for which allogeneic transplantation is consi ...	Trade Name: Fludarabine INN or Proposed INN: FLUDARABINE PHOSPHATE Trade Name: Busilvex INN or Proposed ...	King's College Hospital NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes	27	Phase 2	United Kingdom
8	NCT01499147 (ClinicalTrials.gov)	February 2000	23/11/2011	Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies	Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies	Acute Myeloid Leukemia;Acute Leukemia;Chronic Myelogenous Leukemia;Malignant Lymphoma;Hodgkin's Dise ...	Drug: fludarabine /busulfan;Drug: fludarabine / melphalan;Drug: ATG	University of Illinois at Chicago	NULL	Completed	10 Years	65 Years	All	100	N/A	United States
9	NCT00003816 (ClinicalTrials.gov)	October 19, 1998	1/11/1999	Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or ...	Allogeneic Blood or Marrow Transplantation for Hematologic Malignancy and Aplastic Anemia	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Myelodysplastic Syndromes;Myelodysplastic/Mye ...	Biological: anti-thymocyte globulin;Drug: busulfan;Drug: carboplatin;Drug: cyclophosphamide;Drug: et ...	Roswell Park Cancer Institute	NULL	Completed	4 Years	70 Years	All	362	Phase 2/Phase 3	United States
10	NCT00003336 (ClinicalTrials.gov)	January 1998	1/11/1999	Pilot Study Of Unrelated UCB Transplant for Non-Malignant Hematologic Conditions	A Pilot Study of Unrelated Umbilical Cord Blood Transplantation in Patients With Severe Aplastic Ane ...	Leukemia;Myelodysplastic Syndromes;Myelodysplastic/Myeloproliferative Diseases	Biological: anti-thymocyte globulin;Drug: busulfan;Drug: cyclophosphamide;Drug: melphalan;Drug: meth ...	Case Comprehensive Cancer Center	National Cancer Institute (NCI)	Completed	N/A	55 Years	Both	6	Phase 2	United States

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