60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details

臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166

16 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR1900023509	2017-01-01	2019-05-31	Allogeneic Hematopoietic Stem Cell Transplantation with Risk-adapted Conditioning Regimens for Child ...	Allogeneic Hematopoietic Stem Cell Transplantation with Risk-adapted Conditioning Regimens for Child ...	aplastic anemia,Refractory Cytopenia of Childhood	1:Fludarabine150 mg/m2 +Cyclophosphamide200 mg/kg+ Thymoglobuline10mg/kg;2:Fludarabine200 mg/m2 +Cyc ...	Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine	NULL	Recruiting		18	Both	1:50;2:50;3:50;		China
2	NCT02833805 (ClinicalTrials.gov)	September 2016	12/7/2016	NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia	A Phase II Trial of Non-Myeloablative (NMA) Conditioning and Transplantation of Partially HLA-Mismat ...	Severe Aplastic Anemia;Aplastic Anemia;Bone Marrow Failure;Immunosuppression	Drug: Thymoglobulin;Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total body irradiation;Drug: ...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	NULL	Completed	N/A	N/A	All	21	Phase 2	United States
3	NCT02745717 (ClinicalTrials.gov)	January 2016	7/4/2016	The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Sever ...	The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Sever ...	Severe Aplastic Anemia	Drug: Thymoglobulin;Procedure: Cord blood;Drug: Cyclosporine Oral Product	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	Ruijin Hospital;Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;Shanghai Tongji Ho ...	Completed	N/A	60 Years	All	60	Phase 4	China
4	NCT02224872 (ClinicalTrials.gov)	August 2014	18/8/2014	Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With R ...	A Phase II Trial of Non-Myeloablative Conditioning and Transplantation of Partially HLA-Mismatched/H ...	Severe Aplastic Anemia;Bone Marrow Failure Syndromes	Procedure: Bone marrow transplant;Drug: Thymoglobulin;Drug: Fludarabine;Drug: Cyclophosphamide;Radia ...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	NULL	Completed	N/A	73 Years	All	18	Phase 2	United States
5	JPRN-UMIN000011134	2012/05/23	08/07/2013	A prospective randomized dose comparison multicenter study of the rabbit anti-thymocyte globulin (th ...	A prospective randomized dose comparison multicenter study of the rabbit anti-thymocyte globulin (th ...	Acquired Aplastic Anemia	2.5 mg/kg/day of Thymoglobulin for 5 days 3.5 mg/kg/day of Thymoglobulin for 5 days	Nagoya University	NULL	Complete: follow-up complete	Not applicable	69years-old	Male and Female	320	Not selected	Japan,Asia(except Japan)
6	NCT01844635 (ClinicalTrials.gov)	May 2012	29/4/2013	Randomised Study Comparing Different Dosages of Rabbit ATG in Patients With SAA	A Prospective Randomized Multicenter Study Comparing Different Dosages of Rabbit Antithymocyte Globu ...	Acquired Aplastic Anemia.	Drug: Thymoglobulin	Nagoya University	NULL	Recruiting	N/A	69 Years	Both	320	Phase 3	Japan
7	JPRN-UMIN000006071	2011/08/01	31/08/2011	Allogeneic hematopoietic stem cell transplantation for aplastic anemia using low-dose anti-thymocyte ...	Allogeneic hematopoietic stem cell transplantation for aplastic anemia using low-dose anti-thymocyte ...	SAA	Conditioning regimen Fludarabine 30mg/m2/day iv day-6,-5,-4,-3 Cyclophosphamide 25mg/kg/day iv day-6,-5 ...	Kanto Study Group for Cell Therapy	NULL	Complete: follow-up complete	16years-old	65years-old	Male and Female	28	Phase 2	Japan
8	EUCTR2007-000902-55-DE (EUCTR)	17/12/2009	29/09/2009	Prospective Phase II Pilot study of Rabbit Antithymocyte globulin(ATG, Thymoglobuline®, Genzyme) wit ...	Prospective Phase II Pilot study of Rabbit Antithymocyte globulin(ATG, Thymoglobuline®, Genzyme) wit ...	Acquired severe aplastic anaemia and transfusion dependent non-severe aplastic anaemia MedDRA versio ...	Trade Name: Thymoglobulin Product Name: Thymoglobuline ®/Thymoglobulin® Product Code: anti-thymocyte gl ...	EBMT (European Group for Blood and Marrow Transplantation)	NULL	Not Recruiting			Female: yes Male: yes	35	Phase 2	France;Germany;United Kingdom
9	NCT00882323 (ClinicalTrials.gov)	November 2008	15/4/2009	Reduced Toxicity Fludarabine (Flu) + Cyclophosphamide (CPM) + Rabbit Antithymocyte Globulin (rATG) C ...	Reduced Toxicity Fludarabine, Cyclophosphamide Plus ThymoglobulinConditioning Regimen for Unrelated ...	Aplastic Anemia	Drug: Cyclophosphamide , Fludarabine, Thymoglobulin	The Korean Society of Pediatric Hematology Oncology	NULL	Recruiting	1 Year	21 Years	Both	33	Phase 2	Korea, Republic of
10	NCT00471848 (ClinicalTrials.gov)	August 2008	9/5/2007	Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic ...	Prospective Phase II Study of Rabbit Antithymocyte Globulin (ATG, Thymoglobuline®, Genzyme) With Cic ...	Aplastic Anemia	Drug: rabbit antithymocyte globulin	European Group for Blood and Marrow Transplantation	Genzyme, a Sanofi Company	Active, not recruiting	16 Years	N/A	Both	35	Phase 2	France;Germany;Italy;Saudi Arabia;Switzerland;United Kingdom

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