62. 発作性夜間ヘモグロビン尿症 Paroxysmal nocturnal hemoglobinuria Clinical trials / Disease details

臨床試験数 : 292 / 薬物数 : 151 - (DrugBank : 49) / 標的遺伝子数 : 22 - 標的パスウェイ数 : 108

9 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2016-004129-18-LT (EUCTR)	15/03/2019	29/01/2019	An extension study on rVA576 (Coversin) for Patients with PNH and aHUS who received benefit from the ...	CONSERVE: rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study	Paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS) MedDRA ve ...	Product Code: rVA576 INN or Proposed INN: rVA576 Other descriptive name: COVERSIN	Akari Therapeutics Plc	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 3	France;Argentina;Poland;Lithuania;Kazakhstan;Netherlands;Germany;Sri Lanka;United Kingdom;India
2	NCT03588026 (ClinicalTrials.gov)	June 7, 2018	1/6/2018	Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576	Investigational Product ; Coversin. Phase III Safety and Efficacy in Three-Part, Two-Arm, Randomised ...	Paroxysmal Nocturnal Hemoglobinuria (PNH)	Drug: rVA576;Other: Standard of care (SOC)	AKARI Therapeutics	NULL	Completed	18 Years	N/A	All	9	Phase 3	Kazakhstan;Lithuania;Sri Lanka
3	EUCTR2016-004129-18-NL (EUCTR)	14/02/2018	16/11/2017	An extension study on Coversinfor Patients with PNH and aHUS who received benefit from their initial ...	CONSERVE: Coversin Long Term Safety and Efficacy Surveillance Study	Paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS) MedDRA ve ...	Product Name: Coversin Product Code: rVA576 INN or Proposed INN: COVERSIN Other descriptive name: COVER ...	Akari Therapeutics Plc	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 3	Argentina;Poland;Lithuania;Netherlands;United Kingdom
4	EUCTR2016-004129-18-GB (EUCTR)	17/03/2017	21/12/2016	An extension study on rVA576 (Coversin) for Patients with PNH and aHUS who received benefit from the ...	CONSERVE: rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study	Paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS) MedDRA ve ...	Product Code: rVA576 INN or Proposed INN: rVA576 Other descriptive name: rVA576	Akari Therapeutics Plc	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 3	France;Argentina;Poland;Lithuania;Kazakhstan;Netherlands;Germany;Sri Lanka;United Kingdom
5	NCT03829449 (ClinicalTrials.gov)	March 13, 2017	20/12/2018	rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study	CONSERVE: rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study	Paroxysmal Nocturnal Hemoglobinuria	Drug: rVA576 (Coversin)	AKARI Therapeutics	NULL	Terminated	18 Years	N/A	All	15	Phase 3	Poland
6	EUCTR2016-004129-18-PL (EUCTR)	07/03/2017	18/01/2017	An extension study on Coversinfor Patients with PNH and aHUS who received benefit from their initial ...	CONSERVE: rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study	Paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS) MedDRA ve ...	Product Name: rVA576 (Coversin) Product Code: rVA576 INN or Proposed INN: rVA576 (COVERSIN) Other descrip ...	Akari Therapeutics Plc	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 3	France;Argentina;Poland;Lithuania;Kazakhstan;Netherlands;Germany;Sri Lanka;United Kingdom
7	EUCTR2016-002067-33-GB (EUCTR)	18/07/2016	16/08/2016	An Open Clincal Trial of Coversin in Patients with PNH	COBALT: Coversin Global Study: An Open-Label, Safety and Efficacy Trial in PNH Patients	Paroxysmal nocturnal haemoglobinuria (PNH) MedDRA version: 20.0;Level: PT;Classification code 100340 ...	Product Name: Coversin Product Code: rVA576 INN or Proposed INN: COVERSIN Other descriptive name: COVER ...	Akari Therapeutics Plc	NULL	Not Recruiting			Female: yes Male: yes	10	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United Kingdom
8	NCT02591862 (ClinicalTrials.gov)	February 2016	10/9/2015	Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)	Coversinin Paroxysmal Nocturnal Haemoglobinuria (PNH) in Patients With Resistance to Eculizumab Due ...	Paroxysmal Nocturnal Haemoglobinuria (PNH)	Drug: Coversin	AKARI Therapeutics	Radboud University	Completed	18 Years	80 Years	All	6	Phase 2	Netherlands
9	EUCTR2015-003778-34-NL (EUCTR)	13/01/2016	10/12/2015	Coversinin Paroxysmal Nocturnal Haemoglobulinuria (PNH) in patients with resistance to Eculizumab du ...	Coversinin Paroxysmal Nocturnal Haemoglobulinuria (PNH) in patients with resistance to Eculizumab du ...	Coversinin Paroxysmal Nocturnal Haemoglobinuria (PNH) in patients with resistance to Eculizumab due ...	Product Name: Coversin Product Code: rVA576 INN or Proposed INN: Not applicable Other descriptive name: ...	Volution Immuno Pharmaceuticals (UK) Ltd	NULL	Not Recruiting			Female: yes Male: yes	6	Phase 2	Netherlands

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