63. 特発性血小板減少性紫斑病 Idiopathic thrombocytopenic purpura Clinical trials / Disease details
臨床試験数 : 391 / 薬物数 : 235 - (DrugBank : 50) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 139
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2200058433 | 2022-04-11 | 2022-04-09 | Belimumab in combination with cyclosporine for corticosteroid-refractory primary immune thrombocytopenia in adults | Efficacy and safety of belliumab in combination with cyclosporine in adults with persistent or chronic corticosteroid-refractory primary immune thrombocytopenia: a single-arm, open, multicenter clinical study | Primary immune thrombocytopenia | Group 1:belimumab and cyclosporine; | The Second Affiliated Hospital of Kunming Medical University | NULL | Pending | Both | Group 1:37; | China | |||
| 2 | ChiCTR2000040991 | 2022-03-02 | 2020-12-16 | Cyclosporine A combined with eltrombopag in the treatment for primary immune thrombocytopenia: a prospective, multicenter, single-arm, open clinical study | Cyclosporine A combined with eltrombopag in the treatment for primary immune thrombocytopenia: a prospective, multicenter, single-arm, open clinical study | primary immune thrombocytopenia | experimental group:Cyclosporine A combined with eltrombopag; | The First Affiliated Hospital, College of Medicine, Zhejiang University | NULL | Recruiting | 18 | 75 | Both | experimental group:28; | Phase 4 | China |
| 3 | ChiCTR2000030603 | 2020-05-01 | 2020-03-08 | A multicenter prospective cohort clinical study of a short-course glucocorticoid therapy regimen for glucocorticoid-dependent immune thrombocytopenia | A multicenter prospective cohort clinical study of a short-course glucocorticoid therapy regimen for glucocorticoid-dependent immune thrombocytopenia | Primary Immune Thrombocytopenia | The short -course glucocorticoid group:treat with glucocorticoid;The eltrombopag group:treat with eltrombopag;The rituximab group:treat with rituximab;Splenectomy group:treat with splenectomy;The azathioprine group:treat with azathioprine;The cyclosporine group:treat with cyclosporine; | The Second Affiliated Hospital of Kunming Medical University | NULL | Recruiting | 18 | 75 | Both | The short -course glucocorticoid group:65;The eltrombopag group:65;The rituximab group:65;Splenectomy group:65;The azathioprine group:65;The cyclosporine group:65; | Phase 4 | China |
| 4 | ChiCTR1900027753 | 2019-12-01 | 2019-11-25 | Efficacy and safety of cyclosporine and azathioprine in patients with refractory ITP | Efficacy and safety of cyclosporine and azathioprine in patients with refractory ITP | Primary Immune Thrombocytopenia | Group 1:Using cyclosporine A for treatment;Group 2:Using azathioprine for treatment;Control group:Treatment with glucocorticoids; | the Second Affiliated Hospital of Kunming Medical University | NULL | Pending | 18 | 75 | Both | Group 1:30;Group 2:30;Control group:30; | N/A | China |
| 5 | ChiCTR-OON-17014165 | 2018-01-01 | 2017-12-27 | A clinical trial to evaluate the efficacy and safety of corticosteroids combined with cyclosporin A in the treatment of primary immune thrombocytopenia | A clinical trial to evaluate the efficacy and safety of corticosteroids combined with cyclosporin A in the treatment of primary immune thrombocytopenia | Immune Thrombocytopenia | one:Corticosteroids;two:Corticosteroids combined with Cyclosporin A ; | Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology | NULL | Recruiting | 18 | 65 | Both | one:100;two:100; | China | |
| 6 | NCT01437384 (ClinicalTrials.gov) | September 2011 | 19/9/2011 | Pharmacokinetic and Pharmacodynamic Study in Healthy Subjects Comparing the Interactions Between E5501 and Verapamil and Cyclosporine. | An Open-label, Single-sequence, Four-treatment Period Study to Evaluate Pharmacokinetic and Pharmacodynamic Interactions Between E5501 and Verapamil, and E5501 and Cyclosporine, Known P-glycoprotein Inhibitors in Healthy Subjects | Idiopathic Thrombocytopenic Purpura (ITP) | Drug: E5501 | Eisai Inc. | NULL | Completed | 18 Years | 55 Years | Both | 36 | Phase 1 | United States |