63. 特発性血小板減少性紫斑病 Idiopathic thrombocytopenic purpura Clinical trials / Disease details
臨床試験数 : 391 / 薬物数 : 235 - (DrugBank : 50) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 139
Showing 1 to 10 of 26 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05325593 (ClinicalTrials.gov) | December 2, 2022 | 7/3/2022 | Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia Romiplostim Plus Dexamethasonevs Dexamethasonein Patients With Newly Diagnosed Primary Immune Thromb ... | A Multicentre, Randomized, Open-label Study of Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia A Multicentre, Randomized, Open-label Study of Romiplostim Plus Dexamethasonevs Dexamethasonein Pati ... | Primary Immune Thrombocytopenia | Drug: romiplostim plus dexamethasone;Drug: Dexamethasone | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | NULL | Recruiting | 18 Years | N/A | All | 126 | Phase 3 | Spain |
2 | NCT04812483 (ClinicalTrials.gov) | September 1, 2022 | 1/3/2021 | Immunomodulation With Eltrombopag in ITP | Immunomodulation in Young and Midlife Adults With Newly Diagnosed Primary Immune Thrombocytopenia (ITP): A Randomized Open Label Trial With High-dose Dexamethasone Versus Eltrombopag and High-dose Dexamethasone Immunomodulation in Young and Midlife Adults With Newly Diagnosed Primary Immune Thrombocytopenia (I ... | Primary Immune Thrombocytopenia (ITP) | Drug: Eltrombopag (Revolade®);Drug: standard therapy (without eltrombopag): HD-DXM | University Children's Hospital Basel | Stiftung zur Förderung medizinischer und biologischer Forschung;Novartis Pharmaceuticals;University of Erlangen-Nürnberg, Department of Biology Stiftung zur Förderung medizinischer und biologischer Forschung;Novartis Pharmaceuticals;University ... | Recruiting | 18 Years | 55 Years | All | 24 | Phase 2 | Switzerland |
3 | ChiCTR2100053604 | 2022-01-01 | 2021-11-24 | A clinical study of the efficacy of low-dose prednisone maintenance therapy on adult patients with relapsed chronic/persistent primary immune thrombocytopenia A clinical study of the efficacy of low-dose prednisone maintenance therapy on adult patients with r ... | A clinical study of the efficacy of low-dose prednisone maintenance therapy on adult patients with relapsed chronic/persistent primary immune thrombocytopenia A clinical study of the efficacy of low-dose prednisone maintenance therapy on adult patients with r ... | Primary immune thrombocytopenia | Experimental group:High-dose dexamethasone followed by low-dose prednisone maintenance treatment;Control group:Placebo-controlled after high-dose dexamethasone treatment; Experimental group:High-dose dexamethasonefollowed by low-dose prednisonemaintenance treatment;Contr ... | The Second Affiliated Hospital of Guangxi Medical University | NULL | Recruiting | 18 | 60 | Both | Experimental group:113;Control group:113; | Phase 4 | China |
4 | NCT03692754 (ClinicalTrials.gov) | November 1, 2021 | 29/9/2018 | Atorvastatin in Management of Newly Diagnosed ITP | A Single-center Prospective Randomized Study of Atorvastatin in the Treatment of Newly Diagnosed Primary Immune Thrombocytopenia (ITP) A Single-center Prospective Randomized Study of Atorvastatin in the Treatment of Newly Diagnosed Pri ... | Immune Thrombocytopenia;Purpura, Thrombocytopenic | Drug: Atorvastatin 20mg;Drug: Atorvastatin 10mg;Drug: Dexamethasone | Shandong University | NULL | Not yet recruiting | 18 Years | 80 Years | All | 30 | Phase 2/Phase 3 | China |
5 | NCT05023915 (ClinicalTrials.gov) | August 21, 2021 | 21/8/2021 | A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus DXM Versus DXM in Treatment of ITP A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus ... | High-dose Dexamethasone Plus Diammonium Glycyrrhizinate Enteric-coated Capsule Versus High-dose Dexamethasone in Treatment-naive Primary Immune Thrombocytopenia (ITP): a Multicentre, Randomised, Open-label Trial High-dose DexamethasonePlus Diammonium Glycyrrhizinate Enteric-coated Capsule Versus High-dose Dexam ... | Immune Thrombocytopenia | Drug: dexamethasone;Drug: diammonium glycyrrhizinate enteric-coated capsule | Shandong University | NULL | Recruiting | 18 Years | 80 Years | All | 106 | Phase 2 | China |
6 | ChiCTR2100045747 | 2020-12-01 | 2021-04-23 | Efficacy and safety study of corticosteroids plus hydroxychloroquine in first-line treatment of patients with primary immune thrombocytopenia with positive antinuclear antibody Efficacy and safety study of corticosteroids plus hydroxychloroquine in first-line treatment of pati ... | Efficacy and safety study of corticosteroids plus hydroxychloroquine in first-line treatment of patients with primary immune thrombocytopenia with positive antinuclear antibody Efficacy and safety study of corticosteroids plus hydroxychloroquine in first-line treatment of pati ... | primary immune thrombocytopenia | Experimental group:hydroxychloroquine + Dexamethasone;Control group:Dexamethasone; | Jinshan Hospital, Fudan University | NULL | Recruiting | 18 | Both | Experimental group:51;Control group:51; | Phase 4 | China | |
7 | ChiCTR2000035408 | 2020-08-20 | 2020-08-10 | A randomized controlled study for rituximab in first-line treatment of newly diagnosed immune thrombocytopenia A randomized controlled study for rituximab in first-line treatment of newly diagnosed immune thromb ... | Study of rituximab in first-line treatment of newly diagnosed immune thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Standard dose group:Rituximab (Hanrikang) 375mg/m2, 4 times a week (day 8, 15, 22, 29).;Low-dose group:Rituximab (Hanrikang) 100mg/ time once a week, administered 4 times (day 8, 15, 22 and 29).;Dexamethasone control group:high-dose dexamethasone (HD-DXM), 40mg/d, iv for 4 days (day 1 to day 4), every 15 days, 2 to 4 cycles, until CR or the end of the study.; Standard dose group:Rituximab(Hanrikang) 375mg/m2, 4 times a week (day 8, 15, 22, 29).;Low-dose grou ... | Henan Cancer Hospital | NULL | Recruiting | 18 | 65 | Both | Standard dose group:20;Low-dose group:20;Dexamethasone control group:20; | Phase 4 | China |
8 | ChiCTR1900027735 | 2020-01-01 | 2019-11-24 | Clinical study for high-dose dexamethasone combined with versus without human recombinant thrombopoietin (rhTPO) in the treatment of newly diagnosed primary immune thrombocytopenia (ITP) Clinical study for high-dose dexamethasonecombined with versus without human recombinant thrombopoie ... | Clinical study for high-dose dexamethasone combined with versus without human recombinant thrombopoietin (rhTPO) in the treatment of newly diagnosed primary immune thrombocytopenia (ITP) Clinical study for high-dose dexamethasonecombined with versus without human recombinant thrombopoie ... | Adult newly diagnosed immune thrombocytopenia | Study group:Dexamethasone 40mg/d×4d, recombinant human thrombopoietin (rhTPO) 300U/Kg subcutaneous injection, once/d×14d, if PLT>100×109/L or PLT increase =50×109/L during treatment period RhTPO drug was discontinued; rhTPO and dexamethasone were replaced with prednisone 0.5mg~1mg/kg once a day, 0.2mg/kg per week, and the drug was stopped wit;Control group:Dexamethasone 40mg/d×4d, if the PLT>100×10^9/L or PLT increase =50×10^9/L during the treatment period, dexamethasone was replaced with prednisone 0.5mg~ 1mg/kg orally every day, reduce 0.2mg/kg per week, and quickly reduce the dose within 6~8 weeks.; Study group:Dexamethasone40mg/d×4d, recombinant human thrombopoietin(rhTPO) 300U/Kg subcutaneous inj ... | Department of Hematology, Anhui Provincial Hospital | NULL | Pending | 18 | 80 | Both | Study group:30;Control group:30; | Phase 4 | China |
9 | JPRN-jRCTs041190069 | 01/10/2019 | 25/09/2019 | Clinical study to evaluate the efficacy of dexamethasone Palmitate for idiopathic (immune) thrombocytopenic purpura: ITP. Clinical study to evaluate the efficacy of dexamethasonePalmitate for idiopathic (immune) thrombocyt ... | Clinical Investigation to evaluate the efficacy of dexamethasone palmitate for idiopathic (immune) thrombocytopenic purpura: ITP. - Clinical investigation of Dexamethasone Palmitate for ITP Clinical Investigation to evaluate the efficacy of dexamethasonepalmitate for idiopathic (immune) th ... | Chronic Idiopathic Thrombocytopenic Purpura refractory, immune, thrombocytopenia,;D016553 | Administration of dexamethasone palmitate (5mg/day for 4 days) | Nakayama Takayuki | NULL | Recruiting | >= 20age old | <= 75age old | Both | 7 | Phase 1 | Japan |
10 | NCT03998982 (ClinicalTrials.gov) | June 25, 2019 | 25/6/2019 | Glycyrrhetinic Acid Combined With Dexamethasone in Management of Newly Diagnosed ITP | A Single-center Prospective Randomized Study of Glycyrrhetinic Acid Combined With Dexamethasone in the Treatment of Newly Diagnosed Primary Immune Thrombocytopenia (ITP) A Single-center Prospective Randomized Study of Glycyrrhetinic Acid Combined With Dexamethasonein th ... | Immune Thrombocytopenia | Drug: Glycyrrhetinic Acid;Drug: Dexamethasone | Shandong University | NULL | Recruiting | 18 Years | 80 Years | All | 30 | Phase 4 | China |