63. 特発性血小板減少性紫斑病 Idiopathic thrombocytopenic purpura Clinical trials / Disease details
臨床試験数 : 391 / 薬物数 : 235 - (DrugBank : 50) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 139
Showing 1 to 10 of 85 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05653219 (ClinicalTrials.gov) | February 2, 2023 | 23/11/2022 | A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopagin Primary Immu ... | A Phase 3 Randomized, Double-blind Study of Ianalumab (VAY736) Versus Placebo in Addition to Eltrombopag in Patients With Primary Immune Thrombocytopenia (ITP) Who Had an Insufficient Response or Relapsed After First Line Steroid Treatment (VAYHIT2) A Phase 3 Randomized, Double-blind Study of Ianalumab (VAY736) Versus Placebo in Addition to Eltromb ... | Primary Immune Thrombocytopenia | Biological: Ianalumab;Drug: Eltrombopag;Drug: Placebo | Novartis Pharmaceuticals | NULL | Recruiting | 18 Years | N/A | All | 150 | Phase 3 | Czechia;Hungary;Korea, Republic of;Singapore;United Kingdom |
2 | EUCTR2022-001627-32-ES (EUCTR) | 23/01/2023 | 01/11/2022 | A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltrombopag in primary immune thrombocytopenia (ITP) patients who failed steroids A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltro ... | A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) - VAYHIT2 A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltromb ... | immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immu ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Farmacéutica, S.A. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 150 | Phase 3 | United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;China;Korea, Republic of;Czechia;Turkey;Austria;United Kingdom;Czech Republic;Hungary;Mexico;Belgium;Singapore;Romania;Germany;Norway;Japan United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;Ch ... | ||
3 | EUCTR2022-001627-32-NL (EUCTR) | 29/12/2022 | 31/10/2022 | A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltrombopag in primary immune thrombocytopenia (ITP) patients who failed steroids A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltro ... | A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) - VAYHIT2 A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltromb ... | immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immu ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Pharma AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 150 | Phase 3 | United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;China;Korea, Republic of;Czechia;Turkey;Austria;United Kingdom;Czech Republic;Hungary;Mexico;Argentina;Belgium;Singapore;Romania;Germany;Norway;Japan United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;Ch ... | ||
4 | EUCTR2022-001627-32-CZ (EUCTR) | 05/12/2022 | 20/10/2022 | A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltrombopag in primary immune thrombocytopenia (ITP) patients who failed steroids A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltro ... | A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) - VAYHIT2 A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltromb ... | immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immu ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Pharma AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 150 | Phase 3 | Singapore;United States;Czechia;Malaysia;Thailand;Austria;Netherlands;China;Korea, Republic of;France;Romania;Hungary;Japan;Philippines;United Kingdom;India;Spain;Czech Republic;Turkey;Belgium;Norway;Taiwan;Mexico;Italy;Australia;Germany Singapore;United States;Czechia;Malaysia;Thailand;Austria;Netherlands;China;Korea, Republic of;Franc ... | ||
5 | NCT05583838 (ClinicalTrials.gov) | November 22, 2022 | 12/10/2022 | A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts A Randomized Trial Comparing Optimized rhTPO Treatment With EltrombopagTreatment in Pre-treated ITP ... | Comparing the Efficacy and Safety of Optimized rhTPO Treatment Versus Eltrombopag Treatment in Previously Treated Primary Immune Thrombocytopenia Patients: A Multicenter Randomized Open-label Trial Comparing the Efficacy and Safety of Optimized rhTPO Treatment Versus EltrombopagTreatment in Previo ... | Previously Treated Primary Immune Thrombocytopenia | Drug: rhTPO;Drug: Eltrombopag | Institute of Hematology & Blood Diseases Hospital | The Second Hospital of Hebei Medical University;Xijing Hospital;The Affiliated Hospital of Inner Mongolia Medical University;The Second Affiliated Hospital of Kunming Medical University;Second Affiliated Hospital of Guangzhou Medical University;Shaanxi Provincial People's Hospital;Henan Cancer Hospital;North China University of Science and Technology Affiliated Hospital;Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University;The Second Affiliated Hospital of Dalian Medical University;Second Hospital of Shanxi Medical University;The Second Affiliated Hospital of Harbin Medical University;Daqing Oil Field Hospital;Cangzhou Central Hospital;Yuncheng Central Hospital;Shenyang Sunshine Pharmaceutical Co., LTD. The Second Hospital of Hebei Medical University;Xijing Hospital;The Affiliated Hospital of Inner Mon ... | Recruiting | 18 Years | 85 Years | All | 175 | Phase 4 | China |
6 | NCT04812483 (ClinicalTrials.gov) | September 1, 2022 | 1/3/2021 | Immunomodulation With Eltrombopag in ITP | Immunomodulation in Young and Midlife Adults With Newly Diagnosed Primary Immune Thrombocytopenia (ITP): A Randomized Open Label Trial With High-dose Dexamethasone Versus Eltrombopag and High-dose Dexamethasone Immunomodulation in Young and Midlife Adults With Newly Diagnosed Primary Immune Thrombocytopenia (I ... | Primary Immune Thrombocytopenia (ITP) | Drug: Eltrombopag (Revolade®);Drug: standard therapy (without eltrombopag): HD-DXM | University Children's Hospital Basel | Stiftung zur Förderung medizinischer und biologischer Forschung;Novartis Pharmaceuticals;University of Erlangen-Nürnberg, Department of Biology Stiftung zur Förderung medizinischer und biologischer Forschung;Novartis Pharmaceuticals;University ... | Recruiting | 18 Years | 55 Years | All | 24 | Phase 2 | Switzerland |
7 | NCT05369377 (ClinicalTrials.gov) | June 1, 2022 | 6/5/2022 | Zanubrutinib and Eltrombopag as Second-line Treatment in Adults With Primary Immune Thrombocytopenia | Zanubrutinib and Eltrombopag as Second-line Treatment for Patients With Immune Thrombocytopenia: a Multicentre, Open-label,Randomised, Controlled, Phase 2 Trial Zanubrutinib and Eltrombopagas Second-line Treatment for Patients With Immune Thrombocytopenia: a Mu ... | Immune Thrombocytopenia | Drug: Zanubrutinib;Drug: Eltrombopag | Peking University People's Hospital | Beijing Hospital;The Sixth Medical Center of PLA General Hospital;Beijing Aerospace General Hospital;Qilu Hospital of Shandong University;Beijing Tongren Hospital Beijing Hospital;The Sixth Medical Center of PLA General Hospital;Beijing Aerospace General Hospital ... | Not yet recruiting | 18 Years | 70 Years | All | 150 | Phase 2 | China |
8 | ChiCTR2000040991 | 2022-03-02 | 2020-12-16 | Cyclosporine A combined with eltrombopag in the treatment for primary immune thrombocytopenia: a prospective, multicenter, single-arm, open clinical study Cyclosporine A combined with eltrombopagin the treatment for primary immune thrombocytopenia: a pros ... | Cyclosporine A combined with eltrombopag in the treatment for primary immune thrombocytopenia: a prospective, multicenter, single-arm, open clinical study Cyclosporine A combined with eltrombopagin the treatment for primary immune thrombocytopenia: a pros ... | primary immune thrombocytopenia | experimental group:Cyclosporine A combined with eltrombopag; | The First Affiliated Hospital, College of Medicine, Zhejiang University | NULL | Recruiting | 18 | 75 | Both | experimental group:28; | Phase 4 | China |
9 | NCT04917679 (ClinicalTrials.gov) | September 1, 2020 | 1/12/2020 | Eltrombopag Plus Diacerein vs Eltrombopag in Adult ITP | Eltrombopag Plus Diacerein vs Eltrombopag in Adult Primary Immune Thrombocytopenia: a Multicenter Randomized Controlled Trial EltrombopagPlus Diacerein vs Eltrombopagin Adult Primary Immune Thrombocytopenia: a Multicenter Rand ... | Thrombocytopenia | Drug: Eltrombopag plus diacerein;Drug: Eltrombopag | Qilu Hospital of Shandong University | NULL | Recruiting | 18 Years | N/A | All | 100 | Phase 2 | China |
10 | NCT04518475 (ClinicalTrials.gov) | August 10, 2020 | 12/8/2020 | Eltrombopag Combining Rituximab Versus Eltrombopag in the Management of Primary Immune Thrombocytopenia (ITP) in Adults EltrombopagCombining Rituximab Versus Eltrombopagin the Management of Primary Immune Thrombocytopeni ... | A Multicenter, Randomized, Open-label Study To Compare The Efficacy And Safety Of Eltrombopag Combining Rituximab With Eltrombopag In Adult ITP Patients A Multicenter, Randomized, Open-label Study To Compare The Efficacy And Safety Of EltrombopagCombini ... | Primary Immune Thrombocytopenia (ITP) | Drug: eltrombopag combining rituximab;Drug: eltrombopag | Institute of Hematology & Blood Diseases Hospital | The Second Affiliated Hospital of Kunming Medical University;Henan Cancer Hospital;Tianjin Medical University Second Hospital;The First Affiliated Hospital of Xiamen University;Nantong University The Second Affiliated Hospital of Kunming Medical University;Henan Cancer Hospital;Tianjin Medical U ... | Recruiting | 18 Years | 60 Years | All | 224 | Phase 4 | China |