66. IgA腎症 IgA nephropathy Clinical trials / Disease details
臨床試験数 : 275 / 薬物数 : 258 - (DrugBank : 82) / 標的遺伝子数 : 36 - 標的パスウェイ数 : 140
Showing 1 to 10 of 14 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | EUCTR2016-004507-31-FR (EUCTR) | 27/01/2017 | 02/02/2017 | N/A | N/A - TIGER | MedDRA version: 19.1;Level: PT;Classification code 10021263;Term: IgA nephropathy;System Organ Class: 10038359 - Renal and urinary disorders MedDRA version: 19.1;Level: PT;Classification code 10021263;Term: IgA nephropathy;System Organ Clas ... | Trade Name: METHYLPREDNISOLONE MYLAN Générique Product Name: METHYLPREDNISOLONE MYLAN Générique INN or Proposed INN: Methylprednisolone Other descriptive name: Methylprednisolone Trade Name: PREDNISONE ARROW 20mg Product Name: PREDNISONE ARROW 20mg INN or Proposed INN: PREDNISONE Other descriptive name: PREDNISONE Trade Name: PREDNISONE ARROW 5 mg Product Name: PREDNISONE ARROW 5 mg INN or Proposed INN: Prednisone 5 mg Other descriptive name: Prednisone 5 mg Trade Name: METHYLPREDNISOLONEMYLAN Générique Product Name: METHYLPREDNISOLONEMYLAN Générique INN or P ... | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP) | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 122 | Phase 3 | France | ||
2 | NCT03218852 (ClinicalTrials.gov) | December 2016 | 7/12/2016 | Extended Follow-up of Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy Extended Follow-up of Treatment of PrednisonePlus Cyclophosphamide in Patients With Advanced-stage I ... | An Extended Follow-up of the Prospective Randomized, Controlled, Open-labeled Trial of Prednisone Plus Cyclophosphamide in Patients With Advanced Stage IgA Nephropathy An Extended Follow-up of the Prospective Randomized, Controlled, Open-labeled Trial of PrednisonePlu ... | IgA Nephropathy | Drug: prednisone and cyclophosphamide;Drug: prednisone alone | Guangdong General Hospital | NULL | Active, not recruiting | 18 Years | 70 Years | All | 133 | Phase 4 | China |
3 | NCT02712697 (ClinicalTrials.gov) | June 2016 | 17/11/2015 | Integrative Medicine of IgA Nephropathy | Treatment of Shentong Granules Plus Prednisone on Patients With Severe IgA Nephropathy(Ying-deficiency of the Liver and Kidney Pattern): a Randomized, Double-blind,Placebo-controlled Multicentre Clinical Trial Treatment of Shentong Granules Plus Prednisoneon Patients With Severe IgA Nephropathy(Ying-deficienc ... | Primary IgA Nephropathy | Drug: WM (Shentong Granules);Drug: Hormone (prednisone) | Shanghai University of Traditional Chinese Medicine | RenJi Hospital;Ruijin Hospital;Shanghai 6th People's Hospital;Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;Fudan University RenJi Hospital;Ruijin Hospital;Shanghai 6th People's Hospital;Xinhua Hospital, Shanghai Jiao Tong Un ... | Not yet recruiting | 18 Years | 70 Years | Both | 140 | N/A | China |
4 | NCT01758120 (ClinicalTrials.gov) | December 2012 | 12/12/2012 | Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy | A Prospective Randomized, Controlled, Open-labeled Trial of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy A Prospective Randomized, Controlled, Open-labeled Trial of PrednisonePlus Cyclophosphamide in Patie ... | IgA Nephropathy | Drug: prednisone plus cyclophosphamide;Drug: Prednisone alone | Guangdong General Hospital | NULL | Active, not recruiting | 18 Years | 70 Years | All | 135 | Phase 4 | China |
5 | NCT01451710 (ClinicalTrials.gov) | March 2011 | 7/10/2011 | The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA Nephropathy The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA Nephro ... | The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA Nephropathy The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA Nephro ... | IgA Nephropathy | Drug: Prednisone or Prednisolone | Nanjing University School of Medicine | NULL | Completed | 18 Years | 65 Years | Both | 30 | N/A | China |
6 | ChiCTR-OPN-16010028 | 2011-01-01 | 2016-11-23 | Effects of Tripterygium wilfordii induction therapy to IgA nephropathy patients with heavy proteinuria Effects of Tripterygium wilfordii induction therapy to IgA nephropathy patients with heavy proteinur ... | Effects of Tripterygium wilfordii induction therapy to IgA nephropathy patients with heavy proteinuria Effects of Tripterygium wilfordii induction therapy to IgA nephropathy patients with heavy proteinur ... | IgA nephropathy | Prednisone (PRE) group:1mg/kg prednisone once daily;conventional-dose TW (CTW) group:60 mg TW daily;double-dose TW (DTW) group:?????120mg; Prednisone(PRE) group:1mg/kg prednisoneonce daily;conventional-dose TW (CTW) group:60 mg TW daily;do ... | Yancheng Third People's Hospital | NULL | Completed | 21 | 54 | Both | Prednisone (PRE) group:10;conventional-dose TW (CTW) group:10;double-dose TW (DTW) group:10; | NULL | |
7 | NCT01269021 (ClinicalTrials.gov) | November 2010 | 10/12/2010 | An Multi-site Prospective Study to Assess the Efficacy and Safety of MMF in the Treatment of Proliferative IgA Nephropathy(IgAN) An Multi-site Prospective Study to Assess the Efficacy and Safety of MMF in the Treatment of Prolife ... | Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China. Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, ... | IgA Nephropathy (IgAN) | Drug: mycophenolate mofetil plus lower dose of Prednisone;Drug: Prednisone in full dose | Zhi-Hong Liu, M.D. | NULL | Completed | 18 Years | 60 Years | Both | 176 | N/A | China |
8 | ChiCTR-TRC-10000824 | 2010-01-01 | 2010-04-06 | the clinical effect of Fufang Shenyan Tablet on IgA Nephropathy patients | Multicenter, randomized, double-blind, placebo-controlled clinical research of the clinical effect of Fufang Shenyan Tablet on IgA Nephropathy patients Multicenter, randomized, double-blind, placebo-controlled clinical research of the clinical effect o ... | IgA Nephropathy | the control group:The 24-hour urinary protein 0.5-2.0g: Lotensin 10mg, bid; placebos 2.5g tid; The 24-hour urinary protein 2.0-3.5g: on this basis, combined with prednisone 40mg/d; If patients with hypertension(target blood pressure <=130/80mmHg), used Lotensin 10mg bid alone control it difficultly, give Norvasc 5mg, qd~bid instead; if still poorly controlled, combined with Betaloc 12.5mg, bid;the treatment group:The 24-hour urinary protein 0.5-2.0g: Lotensin 10mg, bid; Fufang Shenyan Tablets 2.5g tid; The 24-hour urinary protein 2.0-3.5g: on this basis, combined with prednisone 40mg/d; If patients with hypertension (target blood pressure <=130/80mmHg), used Lotensin 10mg bid alone control it difficultly, give Norvasc 5mg, qd~bid instead; if still poorly controlled, combined with Betaloc 12.5mg, bid; the control group:The 24-hour urinary protein 0.5-2.0g: Lotensin 10mg, bid; placebos 2.5g tid; The 2 ... | The First Affiliated Hospital of Xi'an Jiaotong University Medical College | NULL | Completed | 18 | 65 | Both | the control group:60;the treatment group:60; | China | |
9 | ChiCTR-TRC-13003702 | 2010-01-01 | 2013-10-12 | Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropathy | Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropathy | IgA Nephropathy | Experimental Group:Chinese Herb Prescription Granule, 6g, Bid, po. 48 weeks;Placebo Comparator:Placebo of Chinese Herb Prescription Granule, 6g, Bid, po. 48 weeks plus prednisone, 0.5mg-1mg/kg/d, po. 48 weeks; Experimental Group:Chinese Herb Prescription Granule, 6g, Bid, po. 48 weeks;Placebo Comparator:Place ... | Department of Nephrology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine | NULL | Completed | 18 | 60 | Both | Experimental Group:100;Placebo Comparator:10; | China | |
10 | NCT01879514 (ClinicalTrials.gov) | January 2010 | 25/3/2013 | Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropath | Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropath | IgA Nephropathy | Drug: Chinese Herb Prescription Granule plus prednisone;Drug: Placebo | Shanghai University of Traditional Chinese Medicine | Shanghai Sixth People's Hospital;RenJi Hospital | Recruiting | 18 Years | 60 Years | Both | 200 | N/A | China |