Pulsed oral sirolimus in autosomal dominant polycystic kidney disease
Pulsed oral sirolimus in autosomal dominant polycystic kidney disease - The Vienna RAP Study
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the development and uncontrolled proliferation of innumerable epithelial-lined cysts that stem from renal tubular cells, which compress and/or destroy vital renal tissue with a gradual decline in renal function, and terminal kidney failure with the need for renal reaplacement therapy. As yet, other than supportive care there is no viable therapy. MedDRA version: 20.0;Level: LLT;Classification code 10036046;Term: Polycystic kidney, autosomal dominant;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the deve ...
Medizinische Universität Wien, Klinische Abteilung für Nephrologie und Dialyse, Universitätsklinik für Innere Medizin 3 Medizinische Universität Wien, Klinische Abteilung für Nephrologie und Dialyse, Universitätsklinik f ...