79. 家族性高コレステロール血症（ホモ接合体） Homozygous familial hypercholesterolemia Clinical trials / Disease details

臨床試験数 : 145 / 薬物数 : 114 - (DrugBank : 26) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 17

18 trials found

diseases per page:

Showing 1 to 10 of 18 diseases

Filter by

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2017-003170-13-AT (EUCTR)	23/07/2019	11/02/2019	Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hyperc ...	An open-label study to evaluate the long-term safety and efficacy of evinacumab in patients with hom ...	Homozygous familial hypercholesterolemia MedDRA version: 21.0;Level: LLT;Classification code 1002060 ...	Product Name: Evinacumab (REGN1500) Product Code: REGN1500 INN or Proposed INN: Evinacumab Other descrip ...	Regeneron Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	121	Phase 3	United States;Greece;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Australia;Sou ...
2	EUCTR2017-003170-13-IT (EUCTR)	18/02/2019	22/01/2021	Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hyperc ...	An open-label study to evaluate the long-term safety and efficacy of evinacumab in patients with hom ...	Homozygous familial hypercholesterolemia MedDRA version: 20.0;Level: LLT;Classification code 1005708 ...	Trade Name: na Product Name: Evinacumab (REGN1500) Product Code: [REGN1500] INN or Proposed INN: Evinacu ...	REGENERON PHARMACEUTICALS, INC.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	100	Phase 3	United States;Czechia;Greece;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Austr ...
3	EUCTR2017-003170-13-GR (EUCTR)	01/02/2019	14/01/2019	Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hyperc ...	An open-label study to evaluate the long-term safety and efficacy of evinacumab in patients with hom ...	Homozygous familial hypercholesterolemia MedDRA version: 21.0;Level: LLT;Classification code 1002060 ...	Product Name: Evinacumab (REGN1500) Product Code: REGN1500 INN or Proposed INN: Evinacumab Other descrip ...	Regeneron Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	121	Phase 3	United States;Czechia;Greece;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Austr ...
4	EUCTR2017-003170-13-CZ (EUCTR)	17/12/2018	11/10/2018	Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hyperc ...	An open-label study to evaluate the long-term safety and efficacy of evinacumab in patients with hom ...	Homozygous familial hypercholesterolemia MedDRA version: 21.0;Level: LLT;Classification code 1002060 ...	Product Name: Evinacumab (REGN1500) Product Code: REGN1500 INN or Proposed INN: Evinacumab Other descrip ...	Regeneron Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	121	Phase 3	United States;Greece;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Australia;Sou ...
5	EUCTR2017-002297-39-DK (EUCTR)	03/09/2018	04/06/2018	An Efficacy and Safety Study of Alirocumab in Children and Adolescents with Homozygous Familial Hype ...	An Open-Label Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents wi ...	Homozygous Familial Hypercholesterolemia MedDRA version: 20.0;Level: PT;Classification code 10020603 ...	Trade Name: Praluent Product Name: Alirocumab Product Code: SAR236553 INN or Proposed INN: Alirocumab Ot ...	Sanofi-Aventis Recherche & Développement	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 3	United States;Taiwan;Slovenia;Spain;Turkey;Austria;Russian Federation;Italy;France;Mexico;Canada;Arg ...
6	EUCTR2017-001388-19-DE (EUCTR)	18/06/2018	23/01/2018	A study to evaluate the safety and efficacy of evinacumab in patients with Hereditary abnormal (high ...	A randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and sa ...	Homozygous familial hypercholesterolemia MedDRA version: 20.1;Level: LLT;Classification code 1002060 ...	Product Name: Evinacumab (REGN1500) Product Code: REGN1500 INN or Proposed INN: Evinacumab Other descrip ...	Regeneron Pharmaceuticals Inc.	NULL	Not Recruiting			Female: yes Male: yes	57	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Greece;Ukraine;Turkey;Austria;Italy;France;Czech Republic;Canada;Australia;South Afric ...
7	EUCTR2017-001388-19-IT (EUCTR)	11/05/2018	11/02/2021	A study to evaluate the safety and efficacy of evinacumab in patients with Hereditary abnormal (high ...	A randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and sa ...	Homozygous familial hypercholesterolemia MedDRA version: 21.0;Level: LLT;Classification code 1002060 ...	Trade Name: Praluent Product Name: Alirocumab Product Code: [REGN7272] INN or Proposed INN: Alirocumab O ...	REGENERON PHARMACEUTICALS, INC.	NULL	Not Recruiting			Female: yes Male: yes	57	Phase 3	United States;Czechia;Greece;Ukraine;Turkey;Austria;Italy;France;Czech Republic;Canada;Australia;Sou ...
8	EUCTR2017-001388-19-GR (EUCTR)	02/05/2018	02/04/2018	A study to evaluate the safety and efficacy of evinacumab in patients with Hereditary abnormal (high ...	A randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and sa ...	Homozygous familial hypercholesterolemia MedDRA version: 21.0;Level: LLT;Classification code 1002060 ...	Product Name: Evinacumab (REGN1500) Product Code: REGN1500 INN or Proposed INN: Evinacumab Other descrip ...	Regeneron Pharmaceuticals Inc.	NULL	Not Recruiting			Female: yes Male: yes	65	Phase 3	United States;Greece;Ukraine;Turkey;Austria;Italy;France;Czech Republic;Canada;Australia;South Afric ...
9	EUCTR2017-001388-19-AT (EUCTR)	23/03/2018	30/01/2018	A study to evaluate the safety and efficacy of evinacumab in patients with Hereditary abnormal (high ...	A randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and sa ...	Homozygous familial hypercholesterolemia MedDRA version: 20.1;Level: LLT;Classification code 1002060 ...	Product Name: Evinacumab (REGN1500) Product Code: REGN1500 INN or Proposed INN: Evinacumab Other descrip ...	Regeneron Pharmaceuticals Inc.	NULL	Not Recruiting			Female: yes Male: yes	57	Phase 3	United States;Greece;Ukraine;Turkey;Austria;Italy;France;Czech Republic;Canada;Australia;South Afric ...
10	EUCTR2017-000351-95-DE (EUCTR)	13/12/2017	17/08/2017	A study to the safety and efficacy of alirocumab in patients with Hereditary abnormal (high) cholest ...	A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SA ...	HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA MedDRA version: 20.0;Level: LLT;Classification code 1005708 ...	Trade Name: Praluent INN or Proposed INN: ALIROCUMAB Other descriptive name: ALIROCUMAB	Regeneron Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	54	Phase 3	France;United States;Czech Republic;Greece;Canada;Ukraine;Turkey;Austria;South Africa;Germany;Italy

First Previous1 2Next Last