84. サルコイドーシス Sarcoidosis Clinical trials / Disease details

臨床試験数 : 149 /  薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169

  
7 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04314193
(ClinicalTrials.gov)		June 1, 202024/2/2020Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary SarcoidosisThe PREDMETH Trial: Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary Sarcoidosis - A Randomized Controlled TrialSarcoidosis, PulmonaryDrug: Methotrexate;Drug: PrednisoloneErasmus Medical CenterSt. Antonius Hospital;LongfondsRecruiting18 YearsN/AAll138Phase 4Netherlands
2NCT03593759
(ClinicalTrials.gov)		January 15, 201927/6/2018Cardiac Sarcoidosis Randomized TrialCardiac Sarcoidosis Multi-Center Randomized Controlled TrialCardiac Sarcoidosis;SarcoidosisDrug: Prednisone or Prednisolone;Drug: MethotrexateOttawa Heart Institute Research CorporationCanadian Institutes of Health Research (CIHR)Recruiting18 YearsN/AAll194Phase 3United States;Canada;Japan;United Kingdom
3NCT03705884
(ClinicalTrials.gov)		January 1, 20188/8/2018PET/MR Imaging In Patients With Cardiac SarcoidosisMolecular Imaging in Cardiovascular Disease Using Hybrid Positron Emission Tomography/Magnetic Resonance Imaging (PET/MR): Cardiac SarcoidosisCardiac SarcoidosisOther: 18F-FDG;Drug: PrednisoloneUniversity of EdinburghNULLUnknown status40 YearsN/AAll40N/AUnited Kingdom
4NCT03324503
(ClinicalTrials.gov)		December 8, 201712/10/2017A Study to Estimate the Effect Sizes of HRCT Endpoints in Response to Glucocorticoid Induction Therapy in Subjects With Pulmonary SarcoidosisA Multicenter, Open-Label Study to Estimate the Effect Sizes of HRCT Endpoints in Response to GLUCOCORTICOID Induction Therapy in Subjects With Pulmonary SarcoidosisSarcoidosis, PulmonaryDrug: Glucocorticoid (prednisone or prednisolone)CelgeneNULLCompleted18 Years65 YearsAll8N/AUnited States;Netherlands;United Kingdom
5JPRN-UMIN000025936
2017/06/1220/02/2017Japanese AntibaCterial drug maNagemEnt for cardiac Sarcoidosis TrialJapanese AntibaCterial drug maNagemEnt for cardiac Sarcoidosis Trial - J-ACNES Cardiac sarcoidosiscombination therapy group:
Prednisolone; Predonisolone start from 30mg/day and continue same dose for one month. After one month, prednisolone decrease 25mg, 20mg, 15mg, 10mg every 2-4 weeks. Finally, maintenance dose of predonisolone is 7.5mg.
Antimicrobial agent; Clarithromycin start from 400mg/day for 24weeks. Doxycycline start 100mg/day for 22 weeks after 2 months of clarithromycin therapy.

Prednisolone; Predonisolone start from 30mg/day and continue same dose for one month. After one month, prednisolone decrease 25mg, 20mg, 15mg, 10mg every 2-4 weeks. Finally, maintenance dose of predonisolone is 7.5mg.		National cerebral and cardiovascular centerNULLComplete: follow-up continuing20years-oldNot applicableMale and Female80Not selectedJapan
6NCT03265405
(ClinicalTrials.gov)		April 1, 201723/8/2017Efficacy and Safety of Two Glucocorticoid Regimens in the Treatment of SarcoidosisEfficacy and Safety of Two Glucocorticoid Regimens in the Treatment of Sarcoidosis: a Randomized Controlled TrialSarcoidosisDrug: Low dose prednisolone;Drug: Medium dose prednisolonePostgraduate Institute of Medical Education and ResearchNULLCompleted18 YearsN/AAll86Phase 4India
7NCT01245036
(ClinicalTrials.gov)		January 200915/11/2010Efficacy of Antituberculous Therapy in Management of SarcoidosisRifampicin and Isoniazid Along With Prednisolone Compared to Prednisolone Alone in Treatment of Sarcoidosis: a Pilot Randomized Controlled TrialSarcoidosis;TuberculosisDrug: Antituberculous therapy along with steroidsPostgraduate Institute of Medical Education and ResearchNULLCompleted15 Years75 YearsBoth100N/AIndia

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