86. 肺動脈性肺高血圧症 Pulmonary arterial hypertension Clinical trials / Disease details


臨床試験数 : 1,205 薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193

  
1 trial found
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1EUCTR2011-001893-24-DE
(EUCTR)
13/10/201121/09/2011To determine oral bioavailability of the oral liquid formulation and potential food effects.Relative bioavailability and food effect study of two oral liquid formulations in comparison to a 1mg tablet of riociguat to characterize its pharmacokinetic properties in healthy male and female adult subjects in a randomized, open label, 5 fold crossover design Children with PH due to • Pulmonary arterial hypertension (PAH) • persistent pulmonary hypertension of the newborn (PPHN)
MedDRA version: 14.0;Level: LLT;Classification code 10037405;Term: Pulmonary hypertension primary;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders
MedDRA version: 14.0;Classification code 10036727;Term: Primary pulmonary hypertension;Classification code 10053592;Term: Newborn persistent pulmonary hypertension;System Organ Class: 10010331 - Congenital, familial and genetic disorders
Product Name: BAY 63-2521 0.3 %
Product Code: BAY 63-2521
INN or Proposed INN: Riociguat
Product Name: BAY 63-2521 0.06 %
Product Code: BAY 63-2521
INN or Proposed INN: Riociguat
Product Name: BAY 63-2521 IR tablets 1 mg
Product Code: BAY 63-2521
INN or Proposed INN: Riociguat
Bayer HealthCare AGNULLNot RecruitingFemale: yes
Male: yes
30Germany