86. 肺動脈性肺高血圧症 Pulmonary arterial hypertension Clinical trials / Disease details
臨床試験数 : 1,205 / 薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2020-004971-42-AT (EUCTR) | 21/12/2021 | 07/09/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Serbia;United States;Czechia;Spain;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Poland;Belgium;Bulgaria;Germany;Latvia;Moldova, Republic of;Bosnia and Herzegovina | ||
| 2 | EUCTR2020-004971-42-DE (EUCTR) | 26/10/2021 | 19/04/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | United States;Czechia;Ukraine;United Kingdom;Spain;Canada;Austria;Latvia;Czech Republic;Belgium;Moldova, Republic of;Poland;Italy;France;Bulgaria;Serbia;Bosnia and Herzegovina;Germany | ||
| 3 | EUCTR2020-004971-42-BG (EUCTR) | 12/10/2021 | 05/07/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Serbia;United States;Czechia;Spain;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Poland;Belgium;Bulgaria;Latvia;Germany;Moldova, Republic of;Bosnia and Herzegovina | ||
| 4 | EUCTR2020-004971-42-PL (EUCTR) | 20/08/2021 | 25/05/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Serbia;United States;Czechia;Spain;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Poland;Belgium;Bulgaria;Latvia;Germany;Moldova, Republic of;Bosnia and Herzegovina | ||
| 5 | EUCTR2020-004971-42-ES (EUCTR) | 22/07/2021 | 22/07/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Serbia;United States;Czechia;Spain;Ukraine;Russian Federation;United Kingdom;Italy;France;Canada;Poland;Belgium;Bulgaria;Germany;Latvia;Bosnia and Herzegovina | ||
| 6 | EUCTR2020-004971-42-CZ (EUCTR) | 22/07/2021 | 06/05/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Serbia;United States;Czechia;Spain;Ukraine;Austria;United Kingdom;Italy;France;Czech Republic;Canada;Poland;Belgium;Bulgaria;Latvia;Germany;Moldova, Republic of;Bosnia and Herzegovina | ||
| 7 | EUCTR2020-004971-42-BE (EUCTR) | 12/07/2021 | 28/04/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Serbia;United States;Czechia;Spain;Ukraine;Russian Federation;United Kingdom;Italy;France;Canada;Belgium;Poland;Bulgaria;Germany;Latvia;Bosnia and Herzegovina | ||
| 8 | EUCTR2020-004971-42-LV (EUCTR) | 09/07/2021 | 22/04/2021 | A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) | A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension - ELEVATE 2 | Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10037400;Term: Pulmonary hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: Rodatristat ethyl Product Code: RVT-1201 INN or Proposed INN: Rodatristat ethyl Other descriptive name: Rodatristat ethyl | Altavant Sciences GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | United States;Serbia;Czechia;Spain;Ukraine;Russian Federation;United Kingdom;Italy;France;Canada;Belgium;Poland;Bulgaria;Latvia;Germany;Bosnia and Herzegovina | ||
| 9 | NCT03924154 (ClinicalTrials.gov) | August 1, 2019 | 5/4/2019 | A Study of RVT-1201 in Patients With Pulmonary Arterial Hypertension (ELEVATE 1) | A Phase 2a, Double-Blind, Placebo-Controlled Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of RVT-1201 in Patients With Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension | Drug: RVT-1201;Drug: Placebo | Altavant Sciences GmbH | Altavant Sciences, Inc.;PPD | Terminated | 18 Years | 75 Years | All | 3 | Phase 2 | United States;Canada |