90. 網膜色素変性症 Retinitis pigmentosa Clinical trials / Disease details

臨床試験数 : 147 /  薬物数 : 176 - (DrugBank : 43) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 110

  
4 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1EUCTR2019-004547-77-GB
(EUCTR)		09/06/202026/02/2020Safety and Tolerability of hRPC in Retinitis PigmentosaFirst-in-human Phase I/IIa, Open-Label, Prospective Study of the Safety and Tolerability of Subretinally Transplanted Human Retinal Progenitor Cells (hRPC) in Subjects with Retinitis Pigmentosa (RP) Retinitis Pigmentosa
MedDRA version: 20.0;Level: PT;Classification code 10038914;Term: Retinitis pigmentosa;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Eye Diseases [C11]		Product Name: human Retinal Progenitor Cells Drug Product
Product Code: hRPC DP
INN or Proposed INN: ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED
Other descriptive name: ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED		ReNeuron LtdNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes		33Phase 2United States;United Kingdom
2NCT03073733
(ClinicalTrials.gov)		March 1, 20172/3/2017Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis PigmentosaA Prospective, Multicenter, Randomized, Study of the Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP)Retinitis PigmentosaBiological: human retinal progenitor cells;Other: Mock injectionjCyte, IncCalifornia Institute for Regenerative Medicine (CIRM)Completed18 YearsN/AAll84Phase 2United States
3NCT02464436
(ClinicalTrials.gov)		December 201518/5/2015Safety and Tolerability of hRPC in Retinitis PigmentosaFirst-in-human Phase I/IIa, Open-Label, Prospective Study of the Safety and Tolerability of Subretinally Transplanted Human Retinal Progenitor Cells (hRPC) in Patients With Retinitis Pigmentosa (RP)Retinitis PigmentosaDrug: hRPCReNeuron LimitedNULLActive, not recruiting18 YearsN/AAll29Phase 1/Phase 2United States;Spain;United Kingdom
4NCT02320812
(ClinicalTrials.gov)		June 201516/12/2014Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis PigmentosaA Prospective, Multicenter, Open-Label, Single-Arm Study of the Safety and Tolerability of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP)Retinitis Pigmentosa (RP)Biological: human retinal progenitor cellsjCyte, IncCalifornia Institute for Regenerative Medicine (CIRM)Completed18 YearsN/AAll28Phase 1/Phase 2United States