DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
96. クローン病
Crohn disease
Clinical trials
/
Disease details
臨床試験数
:
2,442
/
薬物数
:
1,278
- (
DrugBank
:
248
) /
標的遺伝子数
:
142
-
標的パスウェイ数
:
209
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2 trials found
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TrialID
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Public_title
Scientific_title
Condition
Intervention
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sponsor
Secondary_
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Recruitment_
Status
Inclusion_
agemin
Inclusion_
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Inclusion_
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Phase
Countries
1
EUCTR2017-002545-30-GB
(
EUCTR
)
06/11/2017
07/06/2018
Controlled trial to assess low intensity autologous stem cell transplant in refractory Crohn's Disease
Controlled trial to assess low intensity autologous stem cell transplant in refractory Crohn's Disea ...
Autologous Stem cell Transplantation In refractory Crohn's disease - Low Intensity Therapy Evaluation - ASTIClite
Autologous Stem cell Transplantation In refractory Crohn's disease - Low Intensity Therapy Evaluatio ...
Refractory Crohn's Disease
MedDRA version: 20.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Refractory Crohn's Disease
MedDRA version: 20.0;Level: PT;Classification code 10011401;Term: Crohn's ...
Trade Name:
Cyclophosphamide
Product Name:
Cyclophosphamide
INN or Proposed INN:
Cyclophosphamide
monohydrate
INN or Proposed INN:
Cyclophosphamide
monohydrate
Trade Name:
Filgrastim
Product Name:
Filgrastim
INN or Proposed INN:
Filgrastim
Trade Name:
Fludarabine
Product Name:
Fludarabine
INN or Proposed INN:
Fludarabine
phosphate
Trade Name:
Thymoglobuline
Product Name:
Thymoglobuline
INN or Proposed INN:
Rabbit
anti-human thymocyte immunoglobulin
Trade Name:
Cyclophosphamide
Product Name:
Cyclophosphamide
INN or Proposed INN:
Cyclophosphamide
monoh
...
Barts Health NHS Trust
NULL
Not Recruiting
Female: yes
Male: yes
99
Phase 3
United Kingdom
2
NCT01570348
(
ClinicalTrials.gov
)
July 17, 2012
2/4/2012
Crohn's Allogeneic Transplant Study
Allogeneic Hematopoietic Cell Transplantation for Patients With Treatment-Refractory Crohn's Disease: A Phase 2 Study
Allogeneic Hematopoietic Cell Transplantation for Patients With Treatment-Refractory Crohn's Disease ...
Crohn Disease
Procedure: Allogeneic Bone Marrow Transplantation;Drug:
Cyclophosphamide
;Drug:
Fludarabine
Phosphate
;Other: Laboratory Biomarker Analysis;Drug:
Mycophenolate
Mofetil
;Drug:
Mycophenolic Acid
;Other: Quality-of-Life Assessment;Drug: Tacrolimus;Radiation: Total-Body Irradiation
Procedure: Allogeneic Bone Marrow Transplantation;Drug:
Cyclophosphamide
;Drug:
Fludarabine
Phosphate
; ...
Fred Hutchinson Cancer Research Center
National Cancer Institute (NCI);National Institutes of Health (NIH)
Terminated
18 Years
60 Years
All
2
Phase 2
United States