A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory ...
Single center non-randomized study: A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease Single center non-randomized study: A trial of a combination therapy of fecal microbial transplantat ...
AFM therapy arm : three antibiotics, amoxicillin (1500 mg/day), fosfomycin (3000 mg/day) and metronidazole (750 mg/day) are administered orally to patients for 2 weeks. For pediatric patients, amoxicillin (50mg/kg), fosfomycin (120mg/kg) and metronidazole (20mg/kg) are administered orally for 2 weeks (the upper limit is the same amount as adults). FMT arm : Approximately 150 to 250 g of donor stool is diluted with saline (500 mL) and filtered to remove crude components. The diluted and filtered fecal suspension is transferred into the patients colon from cecum to rectum during total colonoscopy. As usual examinations, the patient undergoes biopsy of inflammatory site. A-FMT arm : Patient undergoes FMT two days after AFM therapy. AFM therapy arm : three antibiotics, amoxicillin(1500 mg/day), fosfomycin(3000 mg/day) and metronida ...