97. 潰瘍性大腸炎 Ulcerative colitis Clinical trials / Disease details


臨床試験数 : 2,630 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

  
3 trials found
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PhaseCountries
1NCT05567068
(ClinicalTrials.gov)
February 1, 20231/10/2022Atorvastatin Efficacy and Safety in Patients With Ulcerative ColitisRepurposing Atorvastatin in Patients With Ulcerative Colitis Treated With Mesalamine by Modulation of mTOR/NLRP3 Pathway.Inflammatory Bowel DiseasesDrug: Atorvastatin 80mg;Drug: MesalamineTanta UniversityNULLNot yet recruiting18 Years75 YearsAll44Phase 2NULL
2NCT05561062
(ClinicalTrials.gov)
December 1, 202227/9/2022Atorvastatin in Patients With Ulcerative ColitisCombination of Atorvastatin and Mesalazine to Enhance Anti-inflammatory Effects and Attenuates Progression of Ulcerative ColitisInflammatory Bowel DiseasesDrug: Atorvastatin 80mgTanta UniversityNULLNot yet recruiting18 Years75 YearsAll50Phase 2NULL
3NCT04767984
(ClinicalTrials.gov)
September 24, 202123/2/2021Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative ColitisA Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant P53 by Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated CancerColorectal Carcinoma;Ulcerative ColitisDrug: Atorvastatin Calcium;Procedure: Biopsy of Colon;Procedure: Biospecimen Collection;Drug: Placebo Administration;Other: Questionnaire AdministrationNational Cancer Institute (NCI)NULLRecruiting18 Years70 YearsAll70Phase 2United States