97. 潰瘍性大腸炎 Ulcerative colitis Clinical trials / Disease details

臨床試験数 : 2,630 / 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

17 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000030988	2018/02/01	01/02/2018	Open-label, randomized, two-parallel-arm, single center study to designed to evaluate azathioprine v ...	Open-label, randomized, two-parallel-arm, single center study to designed to evaluate azathioprine v ...	Ulcerative Colitis	Induce azathioprineand continue maintenance therapy by azathioprine Induce adalimumaband continue mai ...	Sakura Medical Center, Toho university	NULL	Pending	15years-old	Not applicable	Male and Female	53	Not applicable	Japan
2	NCT02954159 (ClinicalTrials.gov)	May 18, 2017	14/10/2016	Vedolizumab Monotherapy Vs Combination Therapy With Tacrolimus in UC	Induction of Response and Remission of Vedolizumab Monotherapy Vs Combination Therapy With Tacrolimu ...	Ulcerative Colitis	Drug: Tacrolimus;Drug: Vedolizumab;Other: Placebo	Medical College of Wisconsin	Takeda	Terminated	18 Years	65 Years	All	4	Phase 3	United States
3	JPRN-UMIN000024936	2016/11/30	22/11/2016	Efficacy of additional Calcineurin inhibitors in anti TNF-alfa antibody refractory Ulcerative coliti ...	Efficacy of additional Calcineurin inhibitors in anti TNF-alfa antibody refractory Ulcerative coliti ...	Ulcerative colitis	patients who received Infliximabcontinued to treat every 8 week and who received Adalimumabcontinued ...	Keio University Gastroenterology and Hepatology	NULL	Recruiting	16years-old	150years-old	Male and Female	30	Not selected	Japan
4	JPRN-UMIN000015912	2014/12/15	15/12/2014	Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacro ...	Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacro ...	ulcerative colitis	Tacrolimuswill be decreased gradually three months after it was administered. Adalimumabwill be admi ...	Osaka Medical College	NULL	Recruiting	16years-old	70years-old	Male and Female	50	Not applicable	Japan
5	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus- Effect of ...	rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulc ...	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan
6	JPRN-UMIN000013694	2014/05/13	11/04/2014	Individualized tacrolimus therapy for ulcerative colitis based on CYP3A5 SNPs	Individualized tacrolimustherapy for ulcerative colitis based on CYP3A5 SNPs - Tacrolimustherapy for ...	ulcerative colitis	determine CYP3A5 SNP status increase the initial dosage of tacrolimus	Kitasato University Kitasato Institute Hospital	NULL	Complete: follow-up complete	18years-old	Not applicable	Male and Female	30	Not selected	Japan
7	JPRN-UMIN000013716	2014/04/15	15/04/2014	A study of infliximab administration method for tacrolimus-resistant active ulcerative colitis	A study of infliximab administration method for tacrolimus-resistant active ulcerative colitis - A s ...	ulcerative colitis	After administrating tacrolimusand infliximabfor 6 weeks,tacrolimusis tapered to 0mg. Infliximabmono ...	Yokohama City University Medical Center	NULL	Complete: follow-up complete	16years-old	Not applicable	Male and Female	40	Phase 2	Japan
8	JPRN-UMIN000004201	2013/12/02	14/09/2010	The evaluation of efficacy for remission maintenance with immunomodulator following remission induct ...	The evaluation of efficacy for remission maintenance with immunomodulator following remission induct ...	The patients with moderate to severe active refractory ulcerative colitis	Group of remission maintenance therapy for 48 weeks with immunomodulator at from 2 to 4 weeks follow ...	Osaka City University, Graduate School of Medicine,Department of Gastroenterology	NULL	Complete: follow-up complete	16years-old	65years-old	Male and Female	50	Not selected	Japan
9	JPRN-UMIN000010776	2013/06/01	01/06/2013	An open label randomized controlled trial of tacrolimusversus cyclosporine treatment for severe ulce ...	An open label randomized controlled trial of tacrolimusversus cyclosporine treatment for severe ulce ...	Ulcerative colitis	tacrolimus (Prograf) cyclosporine (Sandimmune)	Chiba University Hospital	NULL	Recruiting	16years-old	65years-old	Male and Female	40	Not selected	Japan
10	JPRN-UMIN000010612	2013/05/01	01/05/2013	A comparative study of the efficacy of tacrolimus with infliximab in intractable ulcerative colitis	A comparative study of the efficacy of tacrolimuswith infliximab in intractable ulcerative colitis - ...	Ulcerative colitis	Tacrolimuswill be administered orally for 10 weeks at the trough level of 10-15 ng/ml for the first ...	Department of Internal Medicine, Division of Gastroenterology and Hepatology, Keio University School ...	NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	130	Phase 4	Japan

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