98. 好酸球性消化管疾患 Eosinophilic gastrointestinal disease Clinical trials / Disease details


臨床試験数 : 172 薬物数 : 149 - (DrugBank : 39) / 標的遺伝子数 : 38 - 標的パスウェイ数 : 135

  
4 trials found
No.TrialIDDate_
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PhaseCountries
1NCT03656380
(ClinicalTrials.gov)
March 20, 201930/8/2018Mepo for EoE StudyA Multi-center, Randomized, Double Blind, Parallel-arm, Placebo Controlled Trial of Mepolizumab for Treatment of Adults and Adolescents With Active Eosinophilic Esophagitis and Dysphagia-predominant SymptomsEoE;Eosinophilic EsophagitisDrug: Mepolizumab 300 mg;Drug: Mepolizumab 100 mg;Other: PlaceboUniversity of North Carolina, Chapel HillGlaxoSmithKline;University of Utah;Northwestern University;MNGI Digestive Health, P.A.Completed16 Years75 YearsAll66Phase 2United States
2NCT00358449
(ClinicalTrials.gov)
September 11, 200627/7/2006Intravenous Mepolizumab In Children With Eosinophilic EsophagitisA Randomized, Double-blind, Parallel Group Clinical Trial to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous Mepolizumab (SB240563)(0.55mg/kg, 2.5mg/kg or 10mg/kg) in Pediatric Subjects With Eosinophilic Esophagitis, Aged 2 to 17 Years (Study MEE103219)Oesophagitis, EosinophilicDrug: mepolizumabGlaxoSmithKlineNULLCompleted2 Years17 YearsAll84Phase 2United States;Australia;Canada;United Kingdom
3EUCTR2005-006074-10-GB
(EUCTR)
15/06/200607/02/2006A randomized, double-blind, parallel group clinical trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous mepolizumab (SB240563) (0.55mg/kg, 2.5mg/kg or 10mg/kg) in pediatric subjects with eosinophilic esophagitis, aged 2 to 17 years - Mepolizumab in paediatric eosinophilic oesophagitisA randomized, double-blind, parallel group clinical trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous mepolizumab (SB240563) (0.55mg/kg, 2.5mg/kg or 10mg/kg) in pediatric subjects with eosinophilic esophagitis, aged 2 to 17 years - Mepolizumab in paediatric eosinophilic oesophagitis Eosinophilic oesophagitisProduct Name: Mepolizumab
Product Code: SB-240563
INN or Proposed INN: Mepolizumab
GlaxoSmithKline Research & Development Ltd.NULLNot Recruiting Female: yes
Male: yes
72 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): noUnited Kingdom
4NCT00266565
(ClinicalTrials.gov)
December 200115/12/2005Anti-Interleukin-5 (IL-5) Study for Hypereosinophilic SyndromeA Phase I/II Study of the Effect of Intravenous Anti-IL-5 (Mepolizumab) SB 240563 on the Outcome and Management of Hypereosinophilic SyndromesHypereosinophilic Syndromes;Eosinophilic Gastroenteritis;Churg-Strauss Syndrome;Eosinophilic EsophagitisDrug: MepolizumabChildren's Hospital Medical Center, CincinnatiNULLCompleted18 Years65 YearsAll24Phase 1/Phase 2United States