2. Amyotrophic lateral sclerosis Clinical trials / Disease details

Clinical trials : 645 / Drugs : 589 - (DrugBank : 163) / Drug target genes : 150 - Drug target pathways : 225

6 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04302870 (ClinicalTrials.gov)	February 27, 2020	4/3/2020	Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial	Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial	Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Drug: Memantine Hydrochloride Oral Solution;Drug: Trazodone Hydrochloride oral solution;Drug: Placebo ...	University of Edinburgh	University College, London;University of Warwick;NHS Lothian	Recruiting	18 Years	N/A	All	750	Phase 2/Phase 3	United Kingdom
2	NCT02118727 (ClinicalTrials.gov)	November 7, 2018	15/4/2014	Therapy in Amyotrophic Lateral Sclerosis (TAME)	Multi-centered Double Blind, Placebo Controlled Study Evaluating the Safety and Efficacy of Memantin ...	Amyotrophic Lateral Sclerosis;Frontal Temporal Dementia	Drug: Memantine;Drug: Placebo (for Memantine)	University of Kansas Medical Center	University of Missouri-Columbia	Completed	18 Years	85 Years	All	90	Phase 2	United States
3	EUCTR2007-002117-39-ES (EUCTR)	31/01/2008	12/02/2008	MEMANTINA(Ebixa X) PARA LA DISCAPACIDAD FUNCIONAL EN LA ESCLEROSIS LATERAL AMIOTRÓFICAMEMANTINE (Ebi ...	MEMANTINA(Ebixa X) PARA LA DISCAPACIDAD FUNCIONAL EN LA ESCLEROSIS LATERAL AMIOTRÓFICAMEMANTINE (Ebi ...	Esclerosis Lateral AmiotroficaAmyotrophic lateral Sclerosis MedDRA version: 9.1;Level: LLT;Classific ...	Trade Name: EBIXA INN or Proposed INN: MEMANTINE HYDROCHLORIDE	Jorge Matias-Guiu Guia	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140		Spain
4	NCT00409721 (ClinicalTrials.gov)	March 2007	8/12/2006	The Effect of Memantineon Functional Outcomes and Motor Neuron Degeneration in Amyotrophic Lateral S ...	A Randomized, Double-blind, Dose Ranging Study to Determine the Effect of Memantineon Functional Out ...	Amyotrophic Lateral Sclerosis	Drug: Memantine	University of Alberta	ALS Association	Completed	18 Years	80 Years	Both	42	Phase 2	Canada
5	NCT00353665 (ClinicalTrials.gov)	July 2005	18/7/2006	Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS)	Phase 2-3 - Memantine for Disability in Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	Drug: Memantine (Ebixa);Drug: riluzole;Drug: Placebo	University of Lisbon	H. Lundbeck A/S	Completed	20 Years	75 Years	Both	63	Phase 2/Phase 3	Portugal
6	NCT01020331 (ClinicalTrials.gov)	June 2005	20/11/2009	Memantine Therapy in Amyotrophic Lateral Sclerosis	Phase IIA Open Label Trial of Memantinein Combination With Riluzole (Customary Care) for the Treatme ...	Amyotrophic Lateral Sclerosis	Drug: Memantine	Phoenix Neurological Associates, LTD	Forest Laboratories	Completed	18 Years	85 Years	Both	20	Phase 2	United States

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