Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MPO [1] MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 [3] 2 , 17, 127 💬
|
| 4 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 5 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
PML [2] PML, RARA 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 6 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 7 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 8 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 9 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 10 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 11 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 12 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 13 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
KCNQ1 [1] KCNQ1 💬
|
Ezogabine Ezogabine 💬
| Ezogabine | 002 [2] 2 , 144 💬
|
| 14 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬
|
Mexiletine Mexiletine 💬
| Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬
|
| 15 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬
|
Quinidine Quinidine 💬
| Quinidine | 002 [3] 2 , 8 , 13 💬
|
| 16 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 17 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 18 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 19 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 20 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 21 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 22 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 23 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 24 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 25 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 26 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 27 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 28 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 29 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 30 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 31 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 32 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 33 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 34 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 35 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 36 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 37 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 38 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 39 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 40 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 41 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 42 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
MC2R [1] MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 43 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A [1] PDE2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 44 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A [1] PDE2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 45 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 46 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 47 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 48 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 49 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 50 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 51 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 52 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 53 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 54 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 55 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 56 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 57 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 58 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
RTN4 [1] RTN4 💬
|
Ozanezumab Ozanezumab 💬
| Ozanezumab | 002 [1] 2 💬
|
| 59 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 60 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 61 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 62 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 63 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
DRD1 [1] DRD1 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 64 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 65 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 66 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 67 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 68 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 69 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 70 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 71 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 72 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 73 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 74 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 75 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
ADRA1A [1] ADRA1A 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 76 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 77 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 78 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 79 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 [2] GRIA1, GRIA2 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 80 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 [2] GRIA1, GRIA2 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 81 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 82 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 83 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 84 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 85 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 86 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 87 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 88 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 89 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 90 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 91 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 92 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 93 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 94 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 95 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 96 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 97 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 98 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B [1] PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 99 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B [1] PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 100 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 101 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 102 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 103 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 104 | Arginine and proline metabolism 💬 3 genes, 8 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 105 | Arginine and proline metabolism 💬 3 genes, 8 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 106 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 107 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 108 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 109 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 110 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 111 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [2] ABL1, SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 112 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 113 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 114 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 115 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 116 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 117 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 118 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 119 | beta-Alanine metabolism 💬 4 genes, 3 drugs (DrugBank) and 17 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 120 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 121 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 122 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 123 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 124 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 125 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 126 | Butanoate metabolism 💬 4 genes, 2 drugs (DrugBank) and 16 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 127 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 128 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 129 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 130 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 131 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 132 | Caffeine metabolism 💬 1 gene, 2 drugs (DrugBank) and 9 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|
| 133 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 134 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 135 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 136 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 137 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 138 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 139 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 140 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 141 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 142 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 143 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 144 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 145 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 146 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 147 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH2 [1] HRH2 💬
|
Cimetidine Cimetidine 💬
| Cimetidine | 002 [2] 2 , 254 💬
|
| 148 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 149 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 150 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 151 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TNNC2 [1] TNNC2 💬
|
Reldesemtiv Reldesemtiv 💬
| Reldesemtiv | 002 [2] 2 , 3 💬
|
| 152 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 153 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 154 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 155 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 156 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CHRM1 [2] CHRM1, CHRM2 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 157 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 158 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 159 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 160 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 161 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 162 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 163 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 164 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 165 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 166 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 167 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 168 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 169 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 170 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 171 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 172 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MC2R [1] MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 173 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 174 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 175 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 176 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 177 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 178 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 179 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 180 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 181 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 182 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 183 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 184 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 185 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 186 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 187 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [1] ADRA2A 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 188 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 [14] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 189 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Guanabenz Guanabenz 💬
| Guanabenz | 002 [2] 2 , 13 💬
|
| 190 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 191 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 192 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 193 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 194 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 195 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 196 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 197 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 198 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 199 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 200 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 201 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 202 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 203 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 204 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬
|
Calusterone Calusterone 💬
| Calusterone | 002 [1] 2 💬
|
| 205 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬
|
Testosterone Testosterone 💬
| Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬
|
| 206 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 207 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 208 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 209 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 210 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 211 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 212 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 213 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 214 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 215 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
SORT1 [1] SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 [2] 2 , 127 💬
|
| 216 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 217 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 218 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 219 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 220 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 221 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
KCNQ1 [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬
|
Ezogabine Ezogabine 💬
| Ezogabine | 002 [2] 2 , 144 💬
|
| 222 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 223 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 224 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 225 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 226 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 227 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 228 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 229 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 230 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 231 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 232 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 233 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 234 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 235 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 236 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 237 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 238 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 239 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 240 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [1] GRIA2 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 241 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [1] GRIA2 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 242 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 243 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 244 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 245 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 246 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 247 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 248 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 249 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Rabeprazole Rabeprazole 💬
| Rabeprazole | 002 [2] 2 , 51 💬
|
| 250 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 251 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 252 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 253 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 254 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 255 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 256 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 257 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 258 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 259 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 260 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 261 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 262 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
MC2R [1] MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 263 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 264 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 265 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MC2R [1] MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 266 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 267 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬
|
Lenograstim Lenograstim 💬
| Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬
|
| 268 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 269 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 270 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 271 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 272 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 273 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 274 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 275 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 276 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 277 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 278 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 279 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 280 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 281 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 282 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 283 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 284 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 285 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 286 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 287 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 288 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 289 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 290 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 291 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 292 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬
|
Mexiletine Mexiletine 💬
| Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬
|
| 293 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬
|
Quinidine Quinidine 💬
| Quinidine | 002 [3] 2 , 8 , 13 💬
|
| 294 | Drug metabolism - cytochrome P450 💬 5 genes, 8 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 295 | Drug metabolism - cytochrome P450 💬 5 genes, 8 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 296 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 297 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 298 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
MPO [1] MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 [3] 2 , 17, 127 💬
|
| 299 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|
| 300 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 15 diseases |
SV2A [1] SV2A 💬
|
Levetiracetam Levetiracetam 💬
| Levetiracetam | 002 [5] 2 , 4 , 6 , 13, 307 💬
|
| 301 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 302 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 303 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 304 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 305 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 306 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
ESR1 [1] ESR1 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 307 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 308 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 309 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 310 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 311 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 312 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 313 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PML [1] PML 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 314 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 315 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 316 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 317 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 318 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 319 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 320 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 321 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 322 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 323 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 324 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 325 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
RARA [1] RARA 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 326 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 327 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 328 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 329 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 330 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 331 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 332 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 333 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 334 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 335 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 336 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 337 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 338 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 339 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 340 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 341 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 342 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 343 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 344 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 345 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 346 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 347 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 348 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 349 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 350 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 351 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 352 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 353 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Rabeprazole Rabeprazole 💬
| Rabeprazole | 002 [2] 2 , 51 💬
|
| 354 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
CHRM3 [1] CHRM3 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 355 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
CHRM3 [1] CHRM3 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 356 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
HRH2 [1] HRH2 💬
|
Cimetidine Cimetidine 💬
| Cimetidine | 002 [2] 2 , 254 💬
|
| 357 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
KCNQ1 [1] KCNQ1 💬
|
Ezogabine Ezogabine 💬
| Ezogabine | 002 [2] 2 , 144 💬
|
| 358 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 359 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 360 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
RARB [1] RARB 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 361 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 362 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 363 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 364 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 365 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B [1] PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 366 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B [1] PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 367 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 368 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 369 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 370 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 371 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 372 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 373 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 374 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 375 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 376 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 377 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 378 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 379 | Glycine, serine and threonine metabolism 💬 5 genes, 10 drugs (DrugBank) and 9 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 380 | Glycine, serine and threonine metabolism 💬 5 genes, 10 drugs (DrugBank) and 9 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 381 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 382 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 383 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 384 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 385 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 386 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 387 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 388 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 389 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 390 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 391 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 392 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬
|
Lenograstim Lenograstim 💬
| Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬
|
| 393 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 394 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL2RA [1] IL2RA 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 395 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 396 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 397 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 398 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 399 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 400 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 401 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 402 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 403 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 404 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 405 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 406 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 407 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 408 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 409 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 410 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 411 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 412 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 413 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
PML [1] PML 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 414 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 415 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 416 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 417 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 418 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 419 | Histidine metabolism 💬 2 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 420 | Histidine metabolism 💬 2 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 421 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 422 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 423 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 424 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 425 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 426 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 427 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 428 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 429 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 430 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 431 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 432 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 433 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 434 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 435 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 436 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 437 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 438 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 439 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 440 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 441 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 442 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 443 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 444 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 445 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 446 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 447 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 448 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 449 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 450 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 451 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 452 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 453 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 454 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 455 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 456 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 457 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 458 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 459 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 460 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 461 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 462 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 463 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 464 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 465 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL2RG [1] IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 466 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 467 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HRH1 [4] HRH1, HTR2A, HTR2B, HTR2C 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 468 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 469 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 470 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 471 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 472 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 473 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
PML [1] PML 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 474 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 475 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 476 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 477 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 478 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
CHRM3 [1] CHRM3 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 479 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
CHRM3 [1] CHRM3 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 480 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
SNAP25 [1] SNAP25 💬
|
Botulinum toxin type A Botulinum toxin type A 💬
| Botulinum toxin type A | 002 [14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
|
| 481 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
SNAP25 [1] SNAP25 💬
|
Rimabotulinumtoxin B Rimabotulinumtoxin B 💬
| Botulinum toxin type B | 002 [4] 2 , 6 , 13, 51 💬
|
| 482 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 483 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 484 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 485 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 486 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 487 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 488 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 489 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 490 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬
|
Lenograstim Lenograstim 💬
| Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬
|
| 491 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 492 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 493 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 494 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 495 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 496 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 497 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 498 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 499 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 500 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 501 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 502 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 503 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 504 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 505 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 506 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 507 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 508 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 509 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 510 | Leukocyte transendothelial migration 💬 13 genes, 14 drugs (DrugBank) and 30 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 511 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 512 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 513 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 514 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 515 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
ROCK2 [1] ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 516 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 517 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 518 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 519 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 520 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 521 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 522 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIA1 [2] GRIA1, GRIA2 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 523 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIA1 [2] GRIA1, GRIA2 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 524 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 525 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 526 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 527 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 528 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 529 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 530 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 531 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 532 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 533 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 534 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 535 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 536 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 537 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 538 | Lysosome 💬 14 genes, 24 drugs (DrugBank) and 6 diseases |
SORT1 [1] SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 [2] 2 , 127 💬
|
| 539 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 540 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 541 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 542 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 543 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 544 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 545 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 546 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 547 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 548 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 549 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 550 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 551 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 552 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 553 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 554 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Rabeprazole Rabeprazole 💬
| Rabeprazole | 002 [2] 2 , 51 💬
|
| 555 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 556 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 557 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 558 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 559 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 560 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 561 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 562 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 563 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 564 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬
|
Dutasteride Dutasteride 💬
| Dutasteride | 001 [2] 1 , 2 💬
|
| 565 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|
| 566 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 567 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 568 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 569 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 570 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ROCK1 [1] ROCK1 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 571 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 572 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 573 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 574 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 575 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 576 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 577 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 578 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 579 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 580 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 581 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 582 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 583 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 584 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 585 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 586 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 587 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 588 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 589 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 590 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 591 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 592 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 [14] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 593 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Guanabenz Guanabenz 💬
| Guanabenz | 002 [2] 2 , 13 💬
|
| 594 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [2] ADRA2A, DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 595 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 596 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 597 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 598 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 599 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 600 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 601 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
| 602 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
| 603 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [2] CYSLTR1, PTGIR 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 604 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 605 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 606 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 607 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 608 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 609 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 610 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 611 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 612 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 613 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 614 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 615 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 616 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 617 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH2 [1] HRH2 💬
|
Cimetidine Cimetidine 💬
| Cimetidine | 002 [2] 2 , 254 💬
|
| 618 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 619 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC2R [1] MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 620 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Betamethasone Betamethasone 💬
| Betamethasone | 002 [8] 2 , 28, 46, 65, 83, 90, 96, 235 💬
|
| 621 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Methylprednisolone Methylprednisolone 💬
| Methylprednisolone | 002 [46] 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
|
| 622 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisone Prednisone 💬
| Prednisone | 002 [45] 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
|
| 623 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 624 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 625 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
SORT1 [1] SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 [2] 2 , 127 💬
|
| 626 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 627 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 628 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 629 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 630 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MPO [1] MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 [3] 2 , 17, 127 💬
|
| 631 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 632 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 633 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 634 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 635 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 636 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 637 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 638 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 639 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 640 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 641 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 642 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 643 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 644 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 645 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 646 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 647 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 648 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 649 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 650 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 651 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [1] RARB 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 652 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 653 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 654 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|
| 655 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1B [2] PDE1B, PDE2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 656 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1B [2] PDE1B, PDE2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 657 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬
|
Calusterone Calusterone 💬
| Calusterone | 002 [1] 2 💬
|
| 658 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬
|
Testosterone Testosterone 💬
| Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬
|
| 659 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 660 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 661 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 662 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 663 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 664 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 665 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 666 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 667 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 668 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 669 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 670 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Rabeprazole Rabeprazole 💬
| Rabeprazole | 002 [2] 2 , 51 💬
|
| 671 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 672 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 673 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 674 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 675 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 676 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 677 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 678 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 679 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 680 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 681 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 682 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CHRM3 [1] CHRM3 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 683 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
KCNQ1 [1] KCNQ1 💬
|
Ezogabine Ezogabine 💬
| Ezogabine | 002 [2] 2 , 144 💬
|
| 684 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 685 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 686 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 687 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 688 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 689 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 690 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 691 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 692 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 693 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 694 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 695 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 696 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 697 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 698 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 699 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 700 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [2] ABL1, SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 701 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 702 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 703 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 704 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 705 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 706 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬
|
Calusterone Calusterone 💬
| Calusterone | 002 [1] 2 💬
|
| 707 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬
|
Testosterone Testosterone 💬
| Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬
|
| 708 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 709 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬
|
Lenograstim Lenograstim 💬
| Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬
|
| 710 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 711 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 712 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 713 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 714 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 715 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 716 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 717 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 718 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PML [3] PML, RARA, RARB 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 719 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 720 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 721 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 722 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 723 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 724 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 725 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 726 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 727 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 728 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 729 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 730 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 731 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 732 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 733 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 734 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 735 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 736 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 737 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 738 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 739 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 740 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 741 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 742 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 743 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 744 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 745 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|
| 746 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 747 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 748 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 749 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 750 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 751 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
MPO [1] MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 [3] 2 , 17, 127 💬
|
| 752 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 753 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 754 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 755 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 756 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 757 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 758 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 759 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CHRM1 [2] CHRM1, CHRM2 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 760 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 761 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬
|
Lenograstim Lenograstim 💬
| Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬
|
| 762 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 763 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 764 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 765 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 766 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 767 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 768 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 769 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 770 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 771 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 772 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 773 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 774 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
IL2RG [1] IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 775 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 776 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 777 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 778 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 779 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 780 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 781 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 782 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 783 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 784 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
SOD1 [1] SOD1 💬
|
Tofersen Tofersen 💬
| Tofersen | 002 [1] 2 💬
|
| 785 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 786 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 787 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 788 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 789 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 790 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 791 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 792 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 793 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 [1] JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 794 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 795 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 796 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 797 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬
|
Calusterone Calusterone 💬
| Calusterone | 002 [1] 2 💬
|
| 798 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬
|
Testosterone Testosterone 💬
| Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬
|
| 799 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 [1] IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 800 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 801 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 802 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
SRD5A2 [1] SRD5A2 💬
|
Dutasteride Dutasteride 💬
| Dutasteride | 001 [2] 1 , 2 💬
|
| 803 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
KCNQ1 [1] KCNQ1 💬
|
Ezogabine Ezogabine 💬
| Ezogabine | 002 [2] 2 , 144 💬
|
| 804 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 805 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 806 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 807 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 808 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 809 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 810 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 811 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 812 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 813 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 814 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 815 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 816 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|
| 817 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 818 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 819 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CNR1 [1] CNR1 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
| 820 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CNR1 [1] CNR1 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
| 821 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
| 822 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 823 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
| 824 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
| 825 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
| 826 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
| 827 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 828 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 829 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 830 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 831 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 832 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 833 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 834 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 835 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 836 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 837 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 838 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 839 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 840 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 841 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Masitinib Masitinib 💬
| Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬
|
| 842 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 843 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 844 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 845 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 846 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 847 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 848 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 849 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 850 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 [2] ADORA1, PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 851 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 [2] ADORA1, PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 852 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 853 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PDE3B [1] PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 854 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PDE3B [1] PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 855 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 856 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 857 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 858 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 859 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 860 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 861 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 862 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 863 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PDE3A [2] PDE3A, PDE3B 💬
|
Levosimendan Levosimendan 💬
| Levosimendan | 002 [1] 2 💬
|
| 864 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 865 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 866 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CNR1 [1] CNR1 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
| 867 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CNR1 [1] CNR1 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
| 868 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 869 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 870 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 871 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 872 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 873 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 874 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 875 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 876 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
| 877 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 878 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CHRM3 [1] CHRM3 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 879 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 880 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
ROCK2 [1] ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 881 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 882 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
| 883 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 884 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 885 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 886 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 887 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 888 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 889 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 890 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Escitalopram Escitalopram 💬
| Escitalopram | 002 [4] 2 , 6 , 13, 46 💬
|
| 891 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 892 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 893 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 894 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 895 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 896 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 897 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 898 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 899 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 900 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [1] RARB 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 901 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 902 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 [1] ADORA1 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 903 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 904 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 905 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 906 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 907 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 908 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 909 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 910 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 911 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 912 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 913 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 914 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 915 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 916 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 917 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬
|
Dutasteride Dutasteride 💬
| Dutasteride | 001 [2] 1 , 2 💬
|
| 918 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Escitalopram Escitalopram 💬
| Escitalopram | 002 [4] 2 , 6 , 13, 46 💬
|
| 919 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
| 920 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SNAP25 [1] SNAP25 💬
|
Botulinum toxin type A Botulinum toxin type A 💬
| Botulinum toxin type A | 002 [14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
|
| 921 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SNAP25 [1] SNAP25 💬
|
Rimabotulinumtoxin B Rimabotulinumtoxin B 💬
| Botulinum toxin type B | 002 [4] 2 , 6 , 13, 51 💬
|
| 922 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 923 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
| 924 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
| 925 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 926 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
| 927 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
| 928 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
| 929 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 930 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 931 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 932 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 933 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 934 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 935 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
| 936 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
| 937 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
| 938 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
| 939 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1B [1] PDE1B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 940 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1B [1] PDE1B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 941 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
|
Mexiletine Mexiletine 💬
| Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬
|
| 942 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
|
Quinidine Quinidine 💬
| Quinidine | 002 [3] 2 , 8 , 13 💬
|
| 943 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN3A [2] SCN3A, SCN9A 💬
|
Lacosamide Lacosamide 💬
| Lacosamide | 002 [4] 2 , 46, 149, 298 💬
|
| 944 | Taurine and hypotaurine metabolism 💬 2 genes, 1 drug (DrugBank) and 14 diseases |
GAD1 [2] GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 945 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
ROCK1 [1] ROCK1 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 946 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 947 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 948 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 949 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 950 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 951 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 952 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 953 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 954 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 955 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 956 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 957 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 958 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 959 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 960 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA [1] RARA 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 961 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
| 962 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
| 963 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 964 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 965 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 966 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 967 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 968 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
ESR1 [1] ESR1 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
| 969 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 970 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 971 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 972 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 973 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 974 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 975 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 976 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 977 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 978 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 979 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 980 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 981 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 982 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
GRIA3 [1] GRIA3 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
| 983 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
GRIA3 [1] GRIA3 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
| 984 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
GRIA3 [1] GRIA3 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
| 985 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 [1] IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 986 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL2RB [1] IL2RB 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 987 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
MPO [1] MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 [3] 2 , 17, 127 💬
|
| 988 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PML [2] PML, RARA 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 989 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 990 | Tryptophan metabolism 💬 5 genes, 10 drugs (DrugBank) and 12 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 991 | Tryptophan metabolism 💬 5 genes, 10 drugs (DrugBank) and 12 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 992 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 993 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 994 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 995 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 996 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 997 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 998 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
GAD1 [2] GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 999 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1000 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1G [1] CACNA1G 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 1001 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 1002 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1003 | Tyrosine metabolism 💬 10 genes, 16 drugs (DrugBank) and 18 diseases |
MAOB [1] MAOB 💬
|
Rasagiline Rasagiline 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 1004 | Tyrosine metabolism 💬 10 genes, 16 drugs (DrugBank) and 18 diseases |
MAOB [1] MAOB 💬
|
Rasagiline tartrate Rasagiline tartrate 💬
| Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬
|
| 1005 | Ubiquitin mediated proteolysis 💬 2 genes, 2 drugs (DrugBank) and 11 diseases |
PML [1] PML 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
| 1006 | Valine, leucine and isoleucine degradation 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 1007 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 1008 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2A [1] ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 1009 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
| 1010 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 1011 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR [1] PTGIR 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 1012 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 1013 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 1014 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1015 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1016 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 1017 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 1018 | Vibrio cholerae infection 💬 3 genes, 10 drugs (DrugBank) and 8 diseases |
KCNQ1 [1] KCNQ1 💬
|
Ezogabine Ezogabine 💬
| Ezogabine | 002 [2] 2 , 144 💬
|
| 1019 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
| 1020 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 1021 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 1022 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 1023 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL2RA [1] IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬
|
| 1024 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬
|
| 1025 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 1026 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1027 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1028 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1029 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
ROCK2 [1] ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 1030 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
| 1031 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
| 1032 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
| 1033 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|