206. Fragile X syndrome Clinical trials / Disease details

Clinical trials : 108 / Drugs : 91 - (DrugBank : 36) / Drug target genes : 52 - Drug target pathways : 77

4 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05367960 (ClinicalTrials.gov)	November 1, 2022	29/4/2022	An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome	An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome	Fragile X Syndrome	Drug: Zatolmilast / BPN14770	Tetra Discovery Partners	NULL	Enrolling by invitation	12 Years	45 Years	Male	300	Phase 3	United States
2	NCT05358886 (ClinicalTrials.gov)	November 1, 2022	27/4/2022	A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome	A Randomized, Double-blind, Placebo-controlled, Parallel Group Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome	Fragile X Syndrome	Drug: BPN14770/ zatolmilast;Drug: Placebo	Tetra Discovery Partners	NULL	Recruiting	18 Years	45 Years	Male	150	Phase 3	United States
3	NCT05163808 (ClinicalTrials.gov)	March 29, 2022	15/12/2021	A Randomized Study of BPN14770 in Male Adolescents (Aged 12 to < 18 Years) With Fragile X Syndrome	A Randomized, Double-blind, Placebo-controlled, Two-Part Study of High and Low Dose BPN14770 in Male Adolescents (Aged 12 to < 18 Years) With Fragile X Syndrome	Fragile X Syndrome	Drug: zatolmilast;Drug: Placebo	Tetra Discovery Partners	NULL	Recruiting	12 Years	18 Years	Male	150	Phase 2/Phase 3	United States
4	NCT03569631 (ClinicalTrials.gov)	July 9, 2018	25/5/2018	A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome	A Randomized, Double-blind, Placebo-controlled, 2-period Crossover Study of BPN14770 in Adult Males With Fragile X Syndrome	Fragile X Syndrome;FXS;Fra(X) Syndrome	Drug: BPN14770;Drug: Placebo	Tetra Discovery Partners	NULL	Completed	18 Years	45 Years	Male	30	Phase 2	United States