265. Lipodystrophy Clinical trials / Disease details

Clinical trials : 112 / Drugs : 155 - (DrugBank : 55) / Drug target genes : 25 - Drug target pathways : 97

3 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01612858 (ClinicalTrials.gov)	June 2011	4/6/2012	Metabolic Abnormalities in HIV-infected Persons	Metabolic Abnormalities in HIV-infected Persons	Lipodystrophy;HIV Infection	Drug: Metformin;Drug: Pioglitazone	Tufts Medical Center	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Completed	18 Years	70 Years	All	20	Phase 4	United States
2	NCT00362440 (ClinicalTrials.gov)	August 2006	9/8/2006	Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome	A Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome: A Randomized, Double-blind, Placebo-controlled Clinical Trial	HIV Lipodystrophy	Drug: Leptin;Drug: Pioglitazone or metformin;Drug: Placebo	Beth Israel Deaconess Medical Center	American Diabetes Association	Completed	18 Years	N/A	All	9	Phase 2	United States
3	NCT00015691 (ClinicalTrials.gov)	April 2001	1/5/2001	Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities	A Randomized, Double-Blind, Placebo-Controlled Study of Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Subjects With Hyperinsulinemia and Elevated Waist/Hip Ratio	HIV Infections;Lipodystrophy;Hyperinsulinemia	Drug: Metformin hydrochloride;Drug: Rosiglitazone maleate	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Completed	18 Years	65 Years	Both	105	N/A	United States