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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
113 valent conjugated pneumococcal vaccine----[1] 265
2150 mg GSK1265744B----[1] 265
3300mg Gemcabene[1] Gemcabene---[1] 265
43TC----[2] 256, 265
5600mg Gemcabene[1] Gemcabene---[1] 265
6Abacavir[1] Abacavir[1] D07057 --[4] 2, 135, 265, 325
7Abacavir 300mg twice daily[1] Abacavir[1] D07057 --[1] 265
8Abacavir sulfate[2] Abacavir,
Sulfate ion		[1] D07057 --[1] 265
9Abacavir sulfate, Lamivudine and Zidovudine[4] Abacavir,
Lamivudine,
Sulfate ion,
Zidovudine		[3] D00353 ,
D00413 ,
D07057 		--[1] 265
10ABC----[2] 256, 265
11Acetate[1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
12ACETYL- L- CARNITINE[1] Levocarnitine[1] D02176 --[1] 265
13Acetylcarnitine[1] Acetylcarnitine---[2] 2, 265
14Acipimox[1] Acipimox[1] D07190 --[2] 78, 265
15AKCEA-ANGPTL3-LRX----[2] 79, 265
16Amplification by PCR and direct sequencing on the entire coding sequence and intron-exons boundaries of the candidate gene----[1] 265
17Amprenavir[1] Amprenavir[1] D00894 --[1] 265
18Antiretroviral/Anti HIV----[1] 265
19Aramchol[1] Aramchol---[1] 265
20Atazanavir[1] Atazanavir[1] D07471 --[1] 265
21Atazanavir (ATV) + ritonavir (RTV), continuation of backbone 2 nucleoside reverse transcriptase inhibitor (NRTIs)[2] Atazanavir,
Ritonavir		[2] D00427 ,
D07471 		--[1] 265
22Atazanavir (Reyataz)[1] Atazanavir[1] D07471 --[1] 265
23Atazanavir/Ritonavir[2] Atazanavir,
Ritonavir		[2] D00427 ,
D07471 		--[1] 265
24Atorvastatin[1] Atorvastatin[1] D07474 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
25Atorvastatin Calcium[2] Atorvastatin,
Calcium		[1] D07474 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[2] 97, 265
26ATV----[1] 265
27Avandia administration for 6-12 weeks----[1] 265
28AZT----[2] 94, 265
29AZT/3TC----[1] 265
30Baricitinib[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
31Berberine[1] Berberine---[2] 97, 265
32BMS-232632----[1] 265
33Caffeine[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
34Calcium[1] Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
35Carnitine[1] Levocarnitine[1] D02176 --[9] 5, 13, 58, 86, 96, 97, 265, 298, 316
36CD----[8] 6, 13, 46, 51, 63, 96, 97, 265
37CD-4 guided therapy interruption----[1] 265
38Cholic Acid[1] Cholic Acid[1] D10699 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
39CoFactor----[2] 265, 288
40Cofactor supplementation (thiamine, riboflavin, L-carnitine)[3] Levocarnitine,
Riboflavin,
Thiamine		[3] D00050 ,
D02176 ,
D08580 		--[1] 265
41COMBIVIR[1] Zidovudine[1] D00413 --[1] 265
42Combivir (zidovudine [AZT] / lamivudine [3TC])[1] Zidovudine[1] D00413 --[1] 265
43Continuation of current HAART (boosted protease inhibitor [PI] combination + 2 NRTIs)----[1] 265
44Didanosine[1] Didanosine[1] D00296 --[2] 25, 265
45Different HAART regimens----[1] 265
46Diosmin[1] Diosmin[1] D07858 --[3] 46, 97, 265
47Diosminex, 500 mg, tabletki powlekane----[1] 265
48Dolutegravir[1] Dolutegravir[1] D10066 --[2] 2, 265
49Dolutegravir / Lamivudine Oral Tablet[2] Dolutegravir,
Lamivudine		[2] D00353 ,
D10066 		--[1] 265
50Dolutegravir 50 MG[1] Dolutegravir[1] D10066 --[1] 265
51Dolutegravir/Lamivudine 50 MG-300 MG Oral Tablet [DOVATO][1] Lamivudine[1] D00353 --[1] 265
52Doravirine[1] Doravirine[1] D10624 --[1] 265
53Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate 100 MG-300 MG-300 MG Oral Tablet [DELSTRIGO][2] Tenofovir,
Tenofovir disoproxil		[1] D06074 --[1] 265
54Efavirenz[1] Efavirenz[1] D00896 --[1] 265
55Efavirenz (EFV)[1] Efavirenz[1] D00896 --[1] 265
56Emtricitabine[1] Emtricitabine[1] D01199 --[4] 25, 93, 265, 325
57Emtricitabine/tenofovir[2] Emtricitabine,
Tenofovir		[2] D01199 ,
D06074 		--[1] 265
58Enfuvirtide[1] Enfuvirtide[1] D02499 --[2] 25, 265
59Enfuvirtide (T20)[1] Enfuvirtide[1] D02499 --[1] 265
60Fenofibrate[1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265
61Gemcabene[1] Gemcabene---[2] 79, 265
62Genotropin (human recombinant Growth hormone)[1] Somatotropin---[1] 265
63Growth hormone[1] Somatotropin---[14] 2, 13, 19, 46, 78, 96, 107, 187, 191, 193, 195, 265, 276, 299
64Growth Hormone Releasing Hormone[1] Somatotropin---[1] 265
65GSK1265744B (sodium salt) containing 14C-GSK1265744B----[1] 265
66High-carbohdyrate breakfast----[1] 265
67High-dose REGN4461----[1] 265
68HIV Anti-retroviral Background Therapy----[1] 265
69Hu Leptin (A-100)[1] Leptin---[1] 265
70Human Growth Hormone[1] Somatotropin---[5] 78, 187, 193, 265, 276
71Human recombinant leptin (metreleptin)[2] Leptin,
Metreleptin		[1] D05014 [1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265
72Indinavir[1] Indinavir[1] D03833 --[1] 265
73ISIS 304801----[1] 265
74Kaletra (lopinavir [LPVr])[1] Lopinavir[1] D01425 --[1] 265
75L-Carnitine[1] Levocarnitine[1] D02176 --[7] 13, 86, 96, 97, 265, 298, 316
76Lamivudine[1] Lamivudine[1] D00353 --[7] 2, 26, 42, 46, 135, 265, 325
77Lamivudine/Zidovudine[2] Lamivudine,
Zidovudine		[2] D00353 ,
D00413 		--[1] 265
78Leptin[1] Leptin---[2] 6, 265
79Lopinavir[1] Lopinavir[1] D01425 --[1] 265
80Lopinavir/Ritonavir[2] Lopinavir,
Ritonavir		[2] D00427 ,
D01425 		--[1] 265
81Lopinavir/ritonavir + nevirapine[3] Lopinavir,
Nevirapine,
Ritonavir		[3] D00427 ,
D00435 ,
D01425 		--[1] 265
82Lopinavir/ritonavir + zidovudine + lamivudine[4] Lamivudine,
Lopinavir,
Ritonavir,
Zidovudine		[4] D00353 ,
D00413 ,
D00427 ,
D01425 		--[1] 265
83Low-Dose REGN4461----[1] 265
84Mecasermin[1] Mecasermin[1] D03297 [2] GHR,
IGF1R 💬		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[5] 78, 96, 168, 265, 299
85Metformin[1] Metformin[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
86METFORMIN HYDROCHLORIDE[1] Metformin[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[5] 81, 158, 265, 299, 301
87METRELEPTIN[1] Metreleptin[1] D05014 [1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265
88Metrelpetin----[1] 265
89Monotherapy (Lopinavir/ritonavir)[2] Lopinavir,
Ritonavir		[2] D00427 ,
D01425 		--[1] 265
90Monotherapy (Lopinavir/ritonavir) + ABC/3TC[2] Lopinavir,
Ritonavir		[2] D00427 ,
D01425 		--[1] 265
91Myalept[1] Metreleptin[1] D05014 [1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265
92N-trans-3-Hexenoyl] Human Growth Hormone Releasing Factor (1-44) Acetate[2] Acetate,
Somatotropin		---[1] 265
93Nelfinavir[1] Nelfinavir[1] D08259 --[3] 49, 265, 331
94Nelfinavir mesylate[1] Nelfinavir[1] D08259 --[1] 265
95Nevirapine[1] Nevirapine[1] D00435 --[1] 265
96Non-nucleoside reverse transcriptase inhibitors----[1] 265
97Norvir[1] Ritonavir[1] D00427 --[2] 265, 299
98NucleomaxX----[1] 265
99Nucleoside analogue sparing HAART regimen----[1] 265
100Nucleoside reverse transcriptase inhibitors----[1] 265
101Obeticholic Acid[1] Obeticholic acid[1] D09360 [1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296
102Pegvisomant[1] Pegvisomant[1] D05394 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 265
103Perform blood cells and fibroblasts biochemical and immuno-labeled investigations----[1] 265
104Pioglitazone[1] Pioglitazone[1] D08378 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
105Pioglitazone or metformin[2] Metformin,
Pioglitazone		[2] D04966 ,
D08378 		[3] PPARG,
PRKAA1,
PRKAA2 💬		[27] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Huntington disease, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Osteoclast differentiation, Oxytocin signaling pathway, PI3K-Akt signaling pathway, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Tight junction, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[1] 265
106Pneumococcal polysaccharide vaccine 23 valent----[1] 265
107Pravastatin[1] Pravastatin[1] D08410 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
108Pravastatin sodium[1] Pravastatin[1] D08410 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 265
109Prevenar13----[2] 19, 265
110Protease inhibitor----[1] 265
111Protease inhibitors----[1] 265
112R-metHuLeptin[1] Metreleptin[1] D05014 [1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265
113Raltegravir[1] Raltegravir[1] D06676 --[4] 13, 26, 93, 265
114RECOMBINANT HUMAN GROWTH HORMONE[1] Somatotropin---[4] 78, 193, 265, 276
115Recombinant human growth hormone + rosiglitazone[2] Rosiglitazone,
Somatotropin		[1] D08491 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 265
116REGN4461----[1] 265
117Reyataz[1] Atazanavir[1] D07471 --[1] 265
118REYATAZ 150MG 60 CPS BL[1] Atazanavir[1] D07471 --[1] 265
119Riboflavin[1] Riboflavin[1] D00050 --[7] 38, 46, 96, 97, 162, 168, 265
120Ritonavir[1] Ritonavir[1] D00427 --[3] 2, 86, 265
121Ritonavir (Norvir)[1] Ritonavir[1] D00427 --[1] 265
122Rosiglitazone[1] Rosiglitazone[1] D08491 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
123Rosiglitazone maleate[1] Rosiglitazone[1] D08491 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[3] 46, 75, 265
124RTV----[1] 265
125Saquinavir[1] Saquinavir[1] D00429 --[2] 86, 265
126Serostim®[somatropin (rDNA origin) for injection][1] Somatotropin---[1] 265
127Setmelanotide[1] Setmelanotide[1] D11927 [1] MC4R 💬[1] Neuroactive ligand-receptor interaction 💬[2] 202, 265
128Simvastatin[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
129Somatropin[1] Somatotropin---[19] 2, 3, 19, 46, 65, 74, 75, 78, 96, 107, 113, 187, 193, 195, 238, 265, 274, 276, 299
130ST200----[1] 265
131Standard continuous antiretroviral therapy----[1] 265
132Stavudine[1] Stavudine[1] D00445 --[1] 265
133Sulfate[1] Sulfate ion---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
134SUSTIVA[1] Efavirenz[1] D00896 --[1] 265
135TAT4 Gel concentration A----[1] 265
136TAT4 Gel concentration B----[1] 265
137Tenofovir[1] Tenofovir disoproxil---[6] 2, 13, 25, 93, 265, 325
138Tenofovir DF[1] Tenofovir[1] D06074 --[1] 265
139Tenofovir disoproxil[1] Tenofovir disoproxil---[2] 93, 265
140Tenofovir Disoproxil Fumarate[2] Tenofovir,
Tenofovir disoproxil		[1] D06074 --[1] 265
141Tesamorelin[1] Tesamorelin[1] D06655 [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265
142Tesamorelin (Egrifta)[1] Tesamorelin[1] D06655 [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[1] 265
143TH9507----[1] 265
144Thiamine[1] Thiamine[1] D08580 --[3] 8, 93, 265
145Tipranavir[1] Tipranavir[1] D08605 --[1] 265
146Total Dietary Replacement----[1] 265
147TRUVADA[1] Emtricitabine[1] D01199 --[1] 265
148Use of lipid-lowering drugs.----[1] 265
149Viral load driven treatment interruption----[1] 265
150Volanesorsen[1] Volanesorsen[1] D11648 [1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265
151VOLANESORSEN SODIUM, ApoC-III Antisense Oligonucleotide[1] Volanesorsen[1] D11648 [1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265
152Zidovudine[1] Zidovudine[1] D00413 --[6] 25, 26, 135, 265, 325, 331