( DrugBank: - )
1 disease
| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 152 | ＰＣＤＨ19関連症候群 | 10 |
152. ＰＣＤＨ19関連症候群
臨床試験数 : 10 / 薬物数 : 7 - (DrugBank : 1) / 標的遺伝子数 : 16 - 標的パスウェイ数 : 7
Showing 1 to 10 of 10 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2018-004496-12-GB (EUCTR) | 14/01/2020 | 18/11/2019 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadher ... | A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female children with protocadherin 19 (PCDH19)-related epilepsy followed by long-term open-label treatment A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 10032061;Term: Other forms of epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 1 ... | Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Prop ... | Marinus Pharmaceuticals, Inc. | NULL | Authorised-recruitment may be ongoing or finished | <pan>br>Female: yes Male: no | 70 | Phase 3 | United States;Israel;United Kingdom;Italy;France;Czech Republic;Hungary;Belgium;Poland;Australia;Denmark;Germany;Netherlands United States;Israel;United Kingdom;Italy;France;Czech Republic;Hungary;Belgium;Poland;Australia;Den ... | ||
| 2 | EUCTR2018-004496-12-HU (EUCTR) | 13/01/2020 | 04/11/2019 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadher ... | A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female children with protocadherin 19 (PCDH19)-related epilepsy followed by long-term open-label treatment A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br> MedDRA version: 20.0;Level: LLT;Classification code 10032061;Term: Other forms of epilepsy;System Organ Class: 100000004852 ;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] protocadherin 19 (PCDH19)-related epilepsy <br> MedDRA version: 20.0;Level: LLT;Class ... | Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Prop ... | Marinus Pharmaceuticals, Inc. | NULL | Authorised-recruitment may be ongoing or finished | <n>br> Female: yes Male: no | 70 | Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): yes Therapeutic use (Phase 4): no Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - ( ... | United States;Spain;Israel;United Kingdom;Italy;France;Hungary;Czech Republic;Poland;Belgium;Australia;Denmark;Germany;Netherlands United States;Spain;Israel;United Kingdom;Italy;France;Hungary;Czech Republic;Poland;Belgium;Austral ... | ||
| 3 | EUCTR2018-004496-12-FR (EUCTR) | 26/09/2019 | 29/04/2019 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadher ... | A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female children with protocadherin 19 (PCDH19)-related epilepsy followed by long-term open-label treatment A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 10032061;Term: Other forms of epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 1 ... | Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT316<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT316<br>INN or Propo ... | Marinus Pharmaceuticals, Inc. | NULL | Authorised-recruitment may be ongoing or finished | <pan>br>Female: yes Male: no | 50 | Phase 3 | United States;France;Hungary;Poland;Spain;Australia;Netherlands;Italy;United Kingdom | ||
| 4 | EUCTR2018-004496-12-NL (EUCTR) | 23/09/2019 | 05/06/2019 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadher ... | A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female children with protocadherin 19 (PCDH19)-related epilepsy followed by long-term open-label treatment A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 10032061;Term: Other forms of epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 1 ... | Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Prop ... | Marinus Pharmaceuticals, Inc. | NULL | Authorised-recruitment may be ongoing or finished | <pan>br>Female: yes Male: no | 30 | Phase 2 | United States;Czechia;Spain;Israel;Italy;United Kingdom;France;Hungary;Belgium;Poland;Australia;Denmark;Netherlands;Germany United States;Czechia;Spain;Israel;Italy;United Kingdom;France;Hungary;Belgium;Poland;Australia;Denm ... | ||
| 5 | EUCTR2018-004496-12-IT (EUCTR) | 26/06/2019 | 20/01/2021 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadhe ... | A double-blind, randomized, placebo-controlled trial of adjunctiveganaxolone treatment in female children with protocadherin 19 (PCDH19)- related epilepsy followed by long-term open-label treatment - N/A A double-blind, randomized, placebo-controlled trial of adjunctiveganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 10032062;Term: Other forms of epilepsy, with intractable epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 1 ... | Product Name: Ganaxolone<br>Product Code: [CCD 1042, MD 9150000, Mepalon 1042, SPT316]<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: [CCD 1042, MD 9150000, Mepalon 1042, SPT316]<br>INN or Pro ... | Marinus Pharmaceuticals, Inc | NULL | Authorised-recruitment may be ongoing or finished | <pan>br>Female: yes Male: no | 70 | Phase 3 | United States;Czechia;Israel;Italy;United Kingdom;France;Hungary;Belgium;Poland;Australia;Denmark;Germany;Netherlands United States;Czechia;Israel;Italy;United Kingdom;France;Hungary;Belgium;Poland;Australia;Denmark;Ge ... | ||
| 6 | NCT03865732 (ClinicalTrials.gov) | May 17, 2019 | 5/3/2019 | Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study) Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related E ... | A Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy Followed by Long-term Open-label Treatment. A Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone Treatment in Female Ch ... | PCDH19-Related Epilepsy | Drug: Ganaxolone;Drug: Placebo | Marinus Pharmaceuticals | NULL | Active, not recruiting | 1 Year | 17 Years | Female | 25 | Phase 2 | United States;Hungary;Italy;Netherlands;Poland;Australia;France |
| 7 | EUCTR2015-001324-36-IT (EUCTR) | 05/06/2015 | 16/04/2015 | Pilot, multicenter study to evaluate the efficacy of the ganaxolone in female children with PCDH19 Pediatric Epilepsy. Pilot, multicenter study to evaluate the efficacy of the ganaxolone in female children with PCDH19 P ... | A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children with PCDH19 Female Pediatric Epilepsy A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children with PCDH19 Female Pediat ... | PCDH19 Female Pediatric Epilepsy (FPE) <br>MedDRA version: 18.0;Level: LLT;Classification code 10032062;Term: Other forms of epilepsy, with intractable epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] PCDH19 Female Pediatric Epilepsy (FPE) <br>MedDRA version: 18.0;Level: LLT;Classification code 10032 ... | Product Name: ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT316<br>INN or Proposed INN: GANAXOLONE<br>Other descriptive name: Ganaxolone, SPT3162, MD 9150000, CCD-1042, Mepalon 1042, (3a-hydroxy-3ß-methyl-5a-pregnan-20-one)<br>Product Name: ganaxolone<br>Product Code: CCD 1042<br>INN or Proposed INN: GANAXOLONE<br>Other descriptive name: Ganaxolone, SPT3162, MD 9150000, CCD-1042, Mepalon 1042, (3a-hydroxy-3ß-methyl-5a-pregnan-20-one) Product Name: ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT316<br>INN or Propo ... | Marinus Pharmaceuticals, Inc. | NULL | Authorised-recruitment may be ongoing or finished | <pan>br>Female: yes Male: no | 10 | United States;Italy | |||
| 8 | NCT02358538 (ClinicalTrials.gov) | March 2015 | 30/1/2015 | A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children With PCDH19 Female Pediat ... | A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies Followed by 52 Week Open-Label Treatment A Multicenter, Open-Label Proof-of-Concept Trial of Ganaxolone in Children With PCDH19 Female Pediat ... | Epilepsy | Drug: Ganaxolone | Marinus Pharmaceuticals | NULL | Active, not recruiting | 2 Years | 18 Years | All | 30 | Phase 2 | United States;Italy |
| 9 | EUCTR2018-004496-12-DK (EUCTR) | 07/11/2019 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadher ... | A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female children with protocadherin 19 (PCDH19)-related epilepsy followed by long-term open-label treatment A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 10032061;Term: Other forms of epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 1 ... | Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT316<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT316<br>INN or Propo ... | Marinus Pharmaceuticals, Inc. | NULL | NA | <pan>br>Female: yes Male: no | 70 | Phase 3 | United States;Spain;Israel;United Kingdom;Italy;France;Czech Republic;Hungary;Poland;Belgium;Denmark;Australia;Germany;Netherlands United States;Spain;Israel;United Kingdom;Italy;France;Czech Republic;Hungary;Poland;Belgium;Denmark ... | |||
| 10 | EUCTR2018-004496-12-PL (EUCTR) | 01/08/2019 | A clinical study with an investigational drug called ganaxolone in female children with protocadherin 19 (PCDH19)-related epilepsy A clinical study with an investigational drug called ganaxolone in female children with protocadher ... | A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female children with protocadherin 19 (PCDH19)-related epilepsy followed by long-term open-label treatment A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in female ch ... | protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 10032061;Term: Other forms of epilepsy;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] protocadherin 19 (PCDH19)-related epilepsy <br>MedDRA version: 20.0;Level: LLT;Classification code 1 ... | Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Proposed INN: GANAXOLONE Product Name: Ganaxolone<br>Product Code: CCD 1042, MD 9150000, Mepalon 1042, SPT3162<br>INN or Prop ... | Marinus Pharmaceuticals, Inc. | NULL | NA | <pan>br>Female: yes Male: no | 30 | Phase 2 | United States;Czechia;Spain;Ireland;Italy;United Kingdom;France;Hungary;Poland;Belgium;Australia;Denmark;Germany;Netherlands United States;Czechia;Spain;Ireland;Italy;United Kingdom;France;Hungary;Poland;Belgium;Australia;Den ... |