Treatment of the genetic defect of cholesterol biosynthetic pathway.
Treatment of the genetic defect of cholesterol biosynthetic pathway by the topical application of statin and cholesterol. Treatment of the genetic defect of cholesterol biosynthetic pathway by the topical application of st ...
To patients, 1% atorvastatin/ 2% cholesterol lotion and/or 1% atorvastatin/ 2% cholesterol ointment, and/or 1% oxiconazole cream are topically applied on the skin. To healthy subjects, administration of atorvastatin or topical application of 1% atorvastatin/ 2% cholesterol is performed once to investigate drug metabolism. To patients, 1% atorvastatin/ 2% cholesterol lotion and/or 1% atorvastatin/ 2% cholesterol ointment, ...