Iron ( DrugBank: Iron )

6 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
18	脊髄小脳変性症（多系統萎縮症を除く。）	1
96	クローン病	12
97	潰瘍性大腸炎	10
238	ビタミンＤ抵抗性くる病/骨軟化症	1
254	ポルフィリン症	2
284	ダイアモンド・ブラックファン貧血	8

18. 脊髄小脳変性症（多系統萎縮症を除く。）

臨床試験数 : 76 / 薬物数 : 98 - (DrugBank : 31) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 65

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00224640 (ClinicalTrials.gov)	March 2005	16/9/2005	Iron-Chelating Therapy and Friedreich Ataxia	Effect of Iron-Chelating Therapy in Friedreich Ataxia. Study Phase I/II	Friedreich Ataxia	Drug: Iron chelating intervention	Assistance Publique - Hôpitaux de Paris	NULL	Completed	13 Years	N/A	Both	15	Phase 1/Phase 2	France

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96. クローン病

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02680756 (ClinicalTrials.gov)	January 2016	9/2/2016	Safety and Efficacy Study of Oral Ferric Maltol Compared to Intravenous IronTo Treat IronDeficiency ...	A Phase 3b, Randomized, Controlled, Multicentre Study With Oral Ferric Maltol (Feraccru) or Intraven ...	Anemia, Iron-Deficiency;Inflammatory Bowel Disease;Crohn's Disease	Drug: Ferric Maltol;Drug: Ferric Carboxy Maltose	Shield Therapeutics	NULL	Completed	18 Years	N/A	All	250	Phase 3	United States;Belgium;France;Germany;Hungary;Spain
2	ChiCTR-DDT-14004402	2014-03-28	2014-03-09	The study of small bowel cleaning by using senna, 20% mannitol, simethicone and three days fasting	The study of small bowel cleaning by using senna, 20% mannitol, simethicone and three days fasting	Obscure gastrointestinal bleeding, irondeficiency anemia , Suspected Crohn’s disease, Suspected smal ...	Group A:20%Mannitol, 0.9% saline;Group B:20%Mannitol, 0.9% saline?simethicone;Group C:20%Mannitol, 0 ...	Sanming First Affiliated Hospital of Fujian Medical University	NULL	Completed	10	85	Both	Group A:60;Group B:60;Group C:60;	4 (Phase 4 study)	China
3	NCT01823029 (ClinicalTrials.gov)	November 2012	25/3/2013	Oxidative Stress and Inflammation Caused by Intravenous Ironin Crohn's Disease Patients With IronDef ...		Crohn's Disease	Drug: erythropoietin;Drug: enteral nutrition.;Drug: injection of iron	Jinling Hospital, China	Ministry of Health, China	Completed	18 Years	75 Years	Both	387	N/A	China
4	EUCTR2010-023589-39-DE (EUCTR)	10/04/2012	16/05/2011	A study of a new ironmedication for people with Crohn's Disease that is in remission and anaemia (lo ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent Crohn's Disease MedDRA version: 17.0;Level: LLT;Classification c ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60		Hungary;Austria;Germany;United Kingdom
5	NCT01991314 (ClinicalTrials.gov)	December 2011	18/11/2013	Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate	Treatment of IronDeficiency Anaemia in Adults and Adolescents With Inflammatory Bowel Disease Using ...	Ulcerative Colitis;Crohn's Disease	Drug: Ferrous sulphate	Queen Mary University of London	NULL	Completed	13 Years	80 Years	All	90	Phase 4	United Kingdom
6	EUCTR2010-023797-39-GB (EUCTR)	12/08/2011	16/07/2011	TREATMENT OF IRON DEFICIENCY ANAEMIA IN ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE	TREATMENT OF IRONDEFICIENCY ANAEMIA IN ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE USING FERROUS SUL ...	Inflammatory bowel disease MedDRA version: 14.1;Level: LLT;Classification code 10045365;Term: Ulcera ...	Trade Name: Ironsulphate 200mg coated tablets Product Name: Ferrous sulphate Product Code: Ferrous sul ...	Barts Health NHS Trust	NULL	Not Recruiting			Female: yes Male: yes	90	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom
7	EUCTR2010-023589-39-GB (EUCTR)	02/08/2011	19/05/2011	A study of a new ironmedication for people with Crohn's Disease that is in remission and anaemia (lo ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent Crohn's Disease MedDRA version: 14.1;Level: PT;Classification co ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Hungary;Austria;Germany;United Kingdom
8	NCT01352221 (ClinicalTrials.gov)	August 2011	10/5/2011	Safety and Efficacy Study of Oral Ferric IronTo Treat IronDeficiency Anaemia in Quiescent Crohn's Di ...	A Prospective, Multicentre, Randomised, Double-blind, Placebo Controlled Study With Oral ST10-021 fo ...	Iron Deficiency Anaemia;Inflammatory Bowel Disease;Crohn's Disease	Drug: ST10;Drug: Placebo oral capsule	Shield Therapeutics	NULL	Completed	18 Years	N/A	All	128	Phase 3	Austria;United Kingdom
9	EUCTR2010-023589-39-AT (EUCTR)	22/06/2011	17/05/2011	A study of a new ironmedication for people with Crohn's Disease that is in remission and anaemia (lo ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent Crohn's Disease MedDRA version: 14.1;Level: PT;Classification co ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60		Hungary;Austria;Germany;United Kingdom
10	NCT00810030 (ClinicalTrials.gov)	October 2008	16/12/2008	FERINJECT for Correction of Anaemia in IBD Patients, FER-IBD-COR	Select A Multi-centre Randomised Prospective Open-label Study to Investigate the Efficacy & Safety o ...	Inflammatory Bowel Disease;Anemia;IronDeficiency;Iron-Deficiency Anemia;Crohn's Disease;Ulcerative C ...	Drug: Ferric carboxymaltose;Drug: Iron Sucrose	Vifor Inc.	Parexel;ClinStar	Completed	18 Years	N/A	Both	484	Phase 3	Austria;Russian Federation

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97. 潰瘍性大腸炎

臨床試験数 : 2,630 / 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05225545 (ClinicalTrials.gov)	November 4, 2019	9/10/2020	Sucrosomial Ironvs. Oral IronSulfate for the Treatment of IronDeficiency Anemia in Patients With Ulc ...	Randomized Controlled Trial of Sucrosomial Ironvs. Oral IronSulfate for the Treatment of IronDeficie ...	Anemia, Iron Deficiency;Ulcerative Colitis	Drug: Sucrosomial Iron;Drug: Oral Iron	American University of Beirut Medical Center	Pharma M	Recruiting	18 Years	N/A	All	30	Phase 3	Lebanon
2	EUCTR2010-023588-16-DE (EUCTR)	10/04/2012	05/05/2011	A study of a new ironmedication for people with ulcerative colitis that is in remission and anaemia ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent ulcerative colitis MedDRA version: 17.0;Level: LLT;Classificatio ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60		Hungary;Austria;Germany;United Kingdom
3	NCT01991314 (ClinicalTrials.gov)	December 2011	18/11/2013	Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate	Treatment of IronDeficiency Anaemia in Adults and Adolescents With Inflammatory Bowel Disease Using ...	Ulcerative Colitis;Crohn's Disease	Drug: Ferrous sulphate	Queen Mary University of London	NULL	Completed	13 Years	80 Years	All	90	Phase 4	United Kingdom
4	EUCTR2010-023797-39-GB (EUCTR)	12/08/2011	16/07/2011	TREATMENT OF IRON DEFICIENCY ANAEMIA IN ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE	TREATMENT OF IRONDEFICIENCY ANAEMIA IN ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE USING FERROUS SUL ...	Inflammatory bowel disease MedDRA version: 14.1;Level: LLT;Classification code 10045365;Term: Ulcera ...	Trade Name: Ironsulphate 200mg coated tablets Product Name: Ferrous sulphate Product Code: Ferrous sul ...	Barts Health NHS Trust	NULL	Not Recruiting			Female: yes Male: yes	90	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom
5	EUCTR2010-023588-16-HU (EUCTR)	11/08/2011	27/05/2011	A study of a new ironmedication for people with ulcerative colitis that is in remission and anaemia ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent ulcerative colitis MedDRA version: 14.1;Level: PT;Classification ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60		Hungary;Austria;Germany;United Kingdom
6	EUCTR2010-023588-16-GB (EUCTR)	02/08/2011	11/05/2011	A study of a new ironmedication for people with ulcerative colitis that is in remission and anaemia ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent ulcerative colitis MedDRA version: 16.0;Level: PT;Classification ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Hungary;Austria;Germany;United Kingdom
7	NCT01340872 (ClinicalTrials.gov)	August 2011	19/4/2011	Safety and Efficacy Study of Oral Ferric IronTo Treat IronDeficiency Anaemia in Quiescent Ulcerative ...	A Prospective, Multicentre, Randomised, Double-blind, Placebo Controlled Study With Oral ST10-021 fo ...	Iron Deficiency Anaemia;Inflammatory Bowel Disease;Ulcerative Colitis	Drug: ST10-021;Drug: Placebo Comparator	Shield Therapeutics	NULL	Completed	18 Years	N/A	All	128	Phase 3	Austria;United Kingdom
8	EUCTR2010-023588-16-AT (EUCTR)	22/06/2011	16/05/2011	A study of a new ironmedication for people with ulcerative colitis that is in remission and anaemia ...	A prospective, multicentre, randomised, double-blind, placebo controlled study with oral ST10-021 fo ...	Irondeficiency anaemia in quiescent ulcerative colitis MedDRA version: 14.1;Level: PT;Classification ...	Product Name: ST10-021 Product Code: ST10-021 Other descriptive name: 3-hydroxy-2-methyl-4H-pyrane-4-o ...	Iron Therapeutics (Switzerland) AG	NULL	Not Recruiting			Female: yes Male: yes	60		Hungary;Austria;Germany;United Kingdom
9	NCT00810030 (ClinicalTrials.gov)	October 2008	16/12/2008	FERINJECT for Correction of Anaemia in IBD Patients, FER-IBD-COR	Select A Multi-centre Randomised Prospective Open-label Study to Investigate the Efficacy & Safety o ...	Inflammatory Bowel Disease;Anemia;IronDeficiency;Iron-Deficiency Anemia;Crohn's Disease;Ulcerative C ...	Drug: Ferric carboxymaltose;Drug: Iron Sucrose	Vifor Inc.	Parexel;ClinStar	Completed	18 Years	N/A	Both	484	Phase 3	Austria;Russian Federation
10	NCT00152841 (ClinicalTrials.gov)	June 2002	7/9/2005	Effect of Ironand Vitamin E Supplementation on Disease Activity in Patients With Either Crohn's Dise ...	Effect of Ironand Antioxidant Vitamins on Disease Activity and Oxidative Stress in Inflammatory Bowe ...	Crohn's Disease;Ulcerative Colitis;Mild or Moderate Anaemia	Drug: Iron supplement 300-600 mg/day;Drug: Vitamin E 800IU	University Health Network, Toronto	Crohn's and Colitis Foundation	Terminated	18 Years	N/A	Both	30	Phase 2	Canada

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238. ビタミンＤ抵抗性くる病/骨軟化症

臨床試験数 : 28 / 薬物数 : 20 - (DrugBank : 9) / 標的遺伝子数 : 3 - 標的パスウェイ数 : 16

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02233322 (ClinicalTrials.gov)	August 2014	27/8/2014	Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.	Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot	Autosomal Dominant Hypophosphatemic Rickets	Dietary Supplement: Iron	Indiana University	NULL	Completed	25 Months	N/A	All	8	N/A	United States

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254. ポルフィリン症

臨床試験数 : 72 / 薬物数 : 53 - (DrugBank : 16) / 標的遺伝子数 : 19 - 標的パスウェイ数 : 35

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02979249 (ClinicalTrials.gov)	December 2016	29/11/2016	Oral Iron for Erythropoietic Protoporphyrias	Effect of Oral IronTherapy on Erythrocyte Protoporphyrin Levels in the Erythropoietic Protoporphyria ...	Erythropoietic Protoporphyria;EPP;X-linked Protoporphyria;XLP	Drug: Oral Iron	Icahn School of Medicine at Mount Sinai	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Completed	18 Years	N/A	All	16	N/A	United States
2	NCT01284946 (ClinicalTrials.gov)	January 2011	26/1/2011	Safety and Efficacy of Oral Deferasirox in Patients With Porphyria Cutanea Tarda	A Phase II, Open Label Clinical Trial Exploring the Safety and the Efficacy of Oral Deferasirox in P ...	Porphyria Cutanea Tarda	Drug: Exjade	Assistance Publique - Hôpitaux de Paris	Association pour l'Etude des Fonctions Digestives (AEFD)	Recruiting	18 Years	N/A	Both	45	Phase 2	France

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284. ダイアモンド・ブラックファン貧血

臨床試験数 : 36 / 薬物数 : 95 - (DrugBank : 34) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 126

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-006322-25-GB (EUCTR)	08/10/2012	14/08/2012	Extending the treatment of Iron Overload	A Phase 2, Open-label, Multicentre, Extension Safety and Tolerability Study for Transfusionally Iron ...	Patients with transfusional ironoverload due to hereditary anemias such as sickle cell disease, beta ...	Product Name: SSP-004184AQ 50 mg Capsule Product Code: SSP-004184AQ 50 mg INN or Proposed INN: deferit ...	Shire Development LLC	NULL	Not Recruiting			Female: yes Male: yes	1500	Phase 2	Egypt;United States;Canada;Thailand;Lebanon;Turkey;Italy;United Kingdom
2	EUCTR2011-006322-25-IT (EUCTR)	20/08/2012	03/09/2012	Extension to the treatment of iron overload with chelation therapy	A PHASE 3, OPEN-LABEL, MILTICENTRE, EXTENSION SAFETY AND TOLERABILITY STUDY FOR TRANSFUSIONALLY IRON ...	ADULT PATIENTS SUFFERING FROM IRONOVERLOAD OF TRANSFUSION-DEPENDENT DOCUMENTED, IN WHICH THE FOLLOWI ...	Product Name: FBS0701 CAPSULE Product Code: FBS0701/SSP004184 INN or Proposed INN: ironchelating agent ...	FERROKIN BIOSCIENCES INC.	NULL	Not Recruiting			Female: yes Male: yes	1500	Phase 3	United States;United Kingdom;Italy
3	EUCTR2011-005675-16-IT (EUCTR)	15/05/2012	02/08/2012	Treatment of chronic iron overload with a chelation therapy (FBS0701)	A Phase 2, 24 Week, Randomized, Open Label, Multi-Center Study to Assess the Safety, Tolerability, P ...	Patients with transfusional ironoverload, with the following primary diagnosis:hereditary anemia (su ...	Product Name: FBS0701 CAPSULE Product Code: FBS0701 INN or Proposed INN: ironchelating agents Product N ...	FERROKIN BIOSCIENCES INC.	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 2	United States;Canada;Lebanon;Turkey;Italy
4	EUCTR2010-019645-25-IT (EUCTR)	04/08/2010	15/07/2010	A Phase 2, 24 Week, Randomized, Open Label, Multi-Center Study to Assess the Safety, Tolerability, a ...	A Phase 2, 24 Week, Randomized, Open Label, Multi-Center Study to Assess the Safety, Tolerability, a ...	Patients with transfusional ironoverload due to hereditary anemias such as sickle cell disease, ß-th ...	Product Name: FBS0701 Capsule Product Code: FBS0701 Product Name: FBS0701 Capsule Product Code: FBS0701 ...	FERROKIN BIOSCIENCES INC.	NULL	Not Recruiting			Female: yes Male: yes	40	Phase 2	United Kingdom;Italy
5	EUCTR2010-019645-25-GB (EUCTR)	19/07/2010	16/06/2010	A 24 week trial to study the safety and tolerability of SSP-004184 in the treatment of patients with ...	A Phase 2, 24 Week, Randomized, Open Label, Multi-Center Study to Assess the Safety, Tolerability, a ...	Patients with transfusional ironoverload due to hereditary anemias such as sickle cell disease, ß-th ...	Product Name: SSP-004184 50 mg Capsule Product Code: SSP-004184 50 mg INN or Proposed INN: Not assigne ...	Shire Development LLC	NULL	Not Recruiting			Female: yes Male: yes	50	Phase 2	United States;Thailand;Turkey;Italy;United Kingdom
6	EUCTR2007-000766-20-GB (EUCTR)	17/07/2008	13/12/2007	A multicenter, randomized, open-label phase II trial evaluating deferasirox compared with deferoxami ...	A multicenter, randomized, open-label phase II trial evaluating deferasirox compared with deferoxami ...	Beta-thalassemia major (TM) or Diamond Blackfan anemia (DBA) or myelodysplastic syndromes (MDS) (low ...	Trade Name: Exjade Product Name: EXJADE Product Code: ICL670 INN or Proposed INN: deferasirox Other desc ...	Novartis Pharma Services AG	NULL	Not Recruiting			Female: yes Male: yes	192	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	Italy;United Kingdom
7	NCT00673608 (ClinicalTrials.gov)	November 2007	5/5/2008	Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver IronLoad in Patients With Transf ...	A Study of Magnetic Resonance Imaging Assessment of Cardiac and Liver IronLoad in Patients With Haem ...	Hemoglobinopathies;Myelodysplastic Syndromes;Other Inherited or Acquired Anaemia;MPD Syndrome;Diamon ...	Drug: deferasirox	Novartis	NULL	Completed	18 Years	N/A	All	118	Phase 4	Australia
8	NCT00235391 (ClinicalTrials.gov)	October 2005	6/10/2005	Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic ...	A Study to Provide Expanded Access of (Exjade®) Deferasirox to Patients With Congenital Disorders of ...	Thalassemia;Sickle Cell Disease;Diamond Blackfan Anemia;Myelofibrosis	Drug: Deferasirox	Novartis Pharmaceuticals	NULL	Completed	2 Years	N/A	All	1683	Phase 3	United States;Belgium;Canada;Germany;Greece;Italy;Netherlands;Spain;Taiwan;Thailand;Turkey;United Ki ...

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