Progerinin ( DrugBank: - )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
191ウェルナー症候群1
333ハッチンソン・ギルフォード症候群1

191. ウェルナー症候群


臨床試験数 : 3 薬物数 : 4 - (DrugBank : 3) / 標的遺伝子数 : 0 - 標的パスウェイ数 : 0
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04512963
(ClinicalTrials.gov)
August 24, 20206/8/2020Phase I Study of Progerinin in Healthy VolunteersA Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose (SAD) Study Including a Food Interaction Study, Followed by a Multiple Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Profile of Progerinin in Healthy VolunteersHutchinson-Gilford Progeria Syndrome;Werner SyndromeDrug: Progerinin;Drug: PlaceboPRG Science & Technology Co., Ltd.Amarex Clinical ResearchCompleted18 Years45 YearsAll64Phase 1United States

333. ハッチンソン・ギルフォード症候群


臨床試験数 : 8 薬物数 : 8 - (DrugBank : 3) / 標的遺伝子数 : 4 - 標的パスウェイ数 : 6
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04512963
(ClinicalTrials.gov)
August 24, 20206/8/2020Phase I Study of Progerinin in Healthy VolunteersA Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose (SAD) Study Including a Food Interaction Study, Followed by a Multiple Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Profile of Progerinin in Healthy VolunteersHutchinson-Gilford Progeria Syndrome;Werner SyndromeDrug: Progerinin;Drug: PlaceboPRG Science & Technology Co., Ltd.Amarex Clinical ResearchCompleted18 Years45 YearsAll64Phase 1United States