INDOCYANINE GREEN ( DrugBank: Indocyanine green )

4 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
22	もやもや病	1
46	悪性関節リウマチ	5
96	クローン病	3
278	巨大リンパ管奇形（頚部顔面病変）	2

22. もやもや病

臨床試験数 : 17 / 薬物数 : 22 - (DrugBank : 17) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 45

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCTs031200402	23/04/2021	08/03/2021	Search for abnormalities of fundus blood vessels in moyamoya disease	Search for abnormalities of fundus blood vessels in moyamoya disease	Moyamoya disease Moyamoya disease	For fluorescein fundus angiography, 500 mg of fluorescein (5 ml vial of aqueous solution containing ...	Akiyama Hideo	NULL	Recruiting	>= 20age old	Not applicable	Both	50	N/A	Japan

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46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04046146 (ClinicalTrials.gov)	December 15, 2019	23/7/2019	Near InfraRed Fluorescence Using Indocyanine Greenand Magnetic Resonance Lymphography of Lymphatic T ...	Near InfraRed Fluorescence Using Indocyanine Greenand Magnetic Resonance Lymphography of Lymphatic T ...	Rheumatoid Arthritis	Drug: Indocyanine Green;Device: MultiSpectral Imaging System	University of Rochester	NULL	Completed	18 Years	89 Years	All	2	Phase 1	United States
2	NCT02680067 (ClinicalTrials.gov)	December 8, 2015	7/12/2015	NIR Fluorescence Imaging of Lymphatic Transport Using ICG	Near InfraRed Fluorescence Imaging of Lymphatic Transport Using Indocyanine Green	Rheumatoid Arthritis	Drug: Indocyanine Green;Device: MultiSpectral Imaging System	University of Rochester	National Institutes of Health (NIH);National Institute of Arthritis and Musculoskeletal and Skin Dis ...	Completed	18 Years	89 Years	All	23	Phase 1	United States
3	NCT02876874 (ClinicalTrials.gov)	December 2014	3/2/2015	Relationship Between the Activity of Rheumatoid Arthritis and Lymph Node Morphology and Lymphatics D ...	the Relationship Between the Activity of Rheumatoid Arthritis(RA) and Popliteal/Epitrochlear Lymph N ...	Rheumatoid Arthritis;Lymph Node Mass;Lymphatic Vessel; Dilatation	Drug: indocyanine green(ICG)	Shanghai University of Traditional Chinese Medicine	NULL	Recruiting	18 Years	65 Years	Both	21	N/A	China
4	EUCTR2013-004006-26-DK (EUCTR)	18/12/2013	18/12/2013	OPAL	Optical images for monitoring treatment changes in rheumatoid arthritis – a longitudinal study with ...	Detection of synovitis and tenosynovitis in the hands of patients with rheumatoid arthritis; Diagnos ...	Trade Name: ICG-Pulsion INN or Proposed INN: 2-{7-[1,1-dimethyl-3-(4-sulfobutyl)-benz[e]indolin-2-yli ...	Knowledge Centre for Rheumatology and Back Diseases	NULL	Not Recruiting			Female: yes Male: yes		Phase 4	Denmark
5	JPRN-UMIN000012399	2013/10/16	26/11/2013	Performance of Rheumascan in healthy subjects and patients with active rheumatoid arthritis	Performance of Rheumascan in healthy subjects and patients with active rheumatoid arthritis - Rheuma ...	Rheumatoid arthritis	Patients with active rheumatoid arthritis (1)Assessment of tender and swollen joints by physical exam ...	Tokyo Medical and Dental University	Diagnostic Imaging Center, Ochanomizu Surugadai Clinic	Complete: follow-up complete	20years-old	Not applicable	Male and Female	9	Not applicable	Japan

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96. クローン病

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR2000035737	2020-10-01	2020-08-16	Application of indocyanine greenfluorescence angiography in preventing anastomotic recurrence after ...	Application of indocyanine greenfluorescence angiography in preventing anastomotic recurrence after ...	Crohn's disease	Experimental group:The scope of surgical resection was determined by indocyanine greenfluorescence a ...	Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine	NULL	Pending	18	70	Both	Experimental group:45;Control group:45;		China
2	NCT04712032 (ClinicalTrials.gov)	July 1, 2020	14/1/2021	Anastomotic Leakage and Value Of Indocyanine Green in Decreasing Leakage Rates	A PHASE III, RANDOMISED CONTROLLED TRIAL ASSESSING THE VALUE OF INDOCYANINE GREENIN THE LEAKAGE RATE ...	Colo-rectal Cancer;Crohn Disease;Resectable Colorectal Carcinoma	Drug: ICG-guided bowel perfusion assessment	Leiden University Medical Center	Medical Center Haaglanden;Catharina Ziekenhuis Eindhoven;Haga Hospital;Jeroen Bosch Ziekenhuis;Amphi ...	Recruiting	18 Years	N/A	All	978	Phase 3	Netherlands
3	ChiCTR-INR-17012532	2017-08-23	2017-09-01	The use of indocyanine greenfluorescent angiography to guide the surgical treatment of Crohn's disea ...	The use of indocyanine greenfluorescent angiography to guide the surgical treatment of Crohn's disea ...	Crohn's disease	Intervention group:Indocyanine green fluorescent angiography;control group:Physiological saline;	Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine	NULL	Recruiting	18	70	Both	Intervention group:40;control group:40;		China

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278. 巨大リンパ管奇形（頚部顔面病変）

臨床試験数 : 19 / 薬物数 : 22 - (DrugBank : 7) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 63

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCTs041190036	03/08/2017	04/06/2019	Visualization of lymphatic malformation	The efficacy of local injection of indocyanine green for visualizing lymphatic malformation	lymphatic malformation	Local injection of indocyanine green	Aitaro Takimoto	NULL	Recruiting	Not applicable	Not applicable	Both	25	Phase 2	Japan
2	JPRN-UMIN000025845	2017/03/01	25/01/2017	The efficacy of local injection of indocyanine green for visualizing lymphatic malformation	The efficacy of local injection of indocyanine greenfor visualizing lymphatic malformation - Visuali ...	lymphatic malformation	Local injection of indocyanine green	Nagoya University Graduate School ofMedicine	NULL	Recruiting	1years-old	30years-old	Male and Female	25	Not selected	Japan

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