Polymorphism Analysis ( DrugBank: - )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
49全身性エリテマトーデス1
60再生不良性貧血2

49. 全身性エリテマトーデス


臨床試験数 : 993 薬物数 : 702 - (DrugBank : 184) / 標的遺伝子数 : 116 - 標的パスウェイ数 : 200
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01060410
(ClinicalTrials.gov)
May 20101/2/2010Exploration of Genotype Based Personalized Prescription of Cyclophosphamide in Systemic Lupus Erythematosus TreatmentExploration of Genetic Polymorphisms Related to Individual Variations of Side Effects of Cyclophosphamide in Systemic Lupus Erythematosus TreatmentLupus Erythematosus, Systemic;Adverse EffectsGenetic: Polymorphism Analysis;Drug: Cyclophosphamide;Other: Pharmacokinetic analysisSun Yat-sen UniversityFirst Affiliated Hospital, Sun Yat-Sen UniversityCompleted12 Years80 YearsBoth222N/AChina

60. 再生不良性貧血


臨床試験数 : 245 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00960050
(ClinicalTrials.gov)
June 200914/8/2009Methemoglobinemia in Patients With Childhood Hematologic Cancer or Aplastic Anemia Treated With DapsoneDapsone Induced Methemoglobinemia Study (DIMS)Leukemia;Lymphoma;Methemoglobinemia;Nonmalignant NeoplasmGenetic: polymorphism analysis;Other: laboratory biomarker analysis;Other: medical chart review;Procedure: assessment of therapy complicationsVanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI)Active, not recruitingN/A22 YearsBoth173United States
2NCT00343785
(ClinicalTrials.gov)
February 200622/6/2006Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow TransplantCyclophosphamide and Antithymocyte Globulin Conditioning Regimen for Marrow Transplantation From HLA-Matched Family Members for Severe Aplastic Anemia: Effect of Marrow Cell Dose on Chronic Graft-vs.-Host Disease: A Multi-Center TrialAplastic AnemiaDrug: cyclophosphamide;Biological: anti-thymocyte globulin;Drug: cyclosporine;Procedure: allogeneic bone marrow transplantation;Drug: methotrexate;Genetic: DNA analysis;Other: flow cytometry;Genetic: polymorphism analysis;Other: laboratory biomarker analysisFred Hutchinson Cancer Research CenterNational Heart, Lung, and Blood Institute (NHLBI)CompletedN/A65 YearsAll21Phase 2United States;Canada