Iloprost ( DrugBank: Iloprost )

4 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
51	全身性強皮症	10
84	サルコイドーシス	1
85	特発性間質性肺炎	1
86	肺動脈性肺高血圧症	39

51. 全身性強皮症

臨床試験数 : 525 / 薬物数 : 565 - (DrugBank : 148) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 217

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04040322 (ClinicalTrials.gov)	October 14, 2019	30/7/2019	Intravenous Iloprostin Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosi ...	A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase 3 Study Evaluating the Safety and ...	Raynaud's Phenomenon Secondary to Systemic Sclerosis	Drug: Placebo IV infusion;Drug: Iloprost Injection, for intravenous use	Eicos Sciences, Inc.	NULL	Completed	18 Years	N/A	All	198	Phase 3	United States
2	NCT03867097 (ClinicalTrials.gov)	March 4, 2019	6/3/2019	Intravenous Iloprostin Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosi ...	A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase 2 Pilot Study Evaluating Intraven ...	Raynaud Phenomenon Secondary to Systemic Sclerosis	Drug: Placebo IV infusion;Drug: Iloprost Injection, for intravenous use	Eicos Sciences, Inc.	NULL	Completed	18 Years	N/A	All	41	Phase 2	United States
3	EUCTR2016-002984-32-IT (EUCTR)	16/02/2017	05/02/2018	ND	Treatment of the Reynaud's Disease associated with ischemic ulcers in patients affected by sistemic ...	SISTEMIC SCLEROSIS MedDRA version: 20.0;Level: LLT;Classification code 10042953;Term: Systemic scler ...	Trade Name: ENDOPROST - 0.05 MG/0.5 ML CONCENTRATO PER SOLUZIONE PER INFUSIONE 1 FIALA Product Name: ...	UNIVERSITÀ CATTOLICA DEL SACRO CUORE- POLICLINICO A. GEMELLI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	238	Phase 4	Italy
4	EUCTR2013-004596-12-IT (EUCTR)	22/01/2014	13/12/2013	Infusion at home ,using a pump device, of a drug that dilates peripheral blood vessels to treat pati ...	HOME INFUSION THERAPY WITH ILOPROSTUSING A PORTABLE SYRINGE PUMP FOR THE TREATMENT OF PERIPHERAL ULC ...	Raynaud's phenomenon and acral ulcers in systemic sclerosis;Therapeutic area: Diseases [C] - Skin an ...	Trade Name: Endoprost Product Name: Endoprost	Azienda ospedaliera universitaria Ospedali Riuniti	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20	Phase 2	Italy
5	NCT00428883 (ClinicalTrials.gov)	January 2007	29/1/2007	High Dose Intravenous N-Acetylcysteine Versus Iloprostfor Early, Rapidly Progressive Diffuse Systemi ...	Rare Disease With Microvascular Involvement: High Dose Intravenous N-Acetylcysteine Versus Iloprostf ...	Scleroderma, Diffuse	Drug: N-acetylcysteine (NAC)	Università Politecnica delle Marche	NULL	Recruiting	18 Years	80 Years	Both	45	Phase 2/Phase 3	Italy
6	EUCTR2006-003957-25-IT (EUCTR)	13/10/2006	09/07/2007	Rare Diseases with microvascular involvement. High Dose Intravenous N-acetylcysteine versus Iloprost ...	Rare Diseases with microvascular involvement. High Dose Intravenous N-acetylcysteine versus Iloprost ...	Systemic Scleroderma MedDRA version: 9.1;Level: LLT;Classification code 10055953;Term: Scleroedema	Trade Name: HIDONACEV 1FL 5G 25ML INN or Proposed INN: Acetylcysteine Trade Name: ENDOPROST 50INFUS ...	AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy
7	EUCTR2006-000905-41-AT (EUCTR)	07/06/2006	08/05/2006	Offene, monozentrische, randomisierte, placebo-kontrollierte, einfach blinde und Observer-blinde kli ...	Offene, monozentrische, randomisierte, placebo-kontrollierte, einfach blinde und Observer-blinde kli ...	Raynaud syndrome with / without systemic sclerosis	Trade Name: Ilomedin Product Name: Ilomedin Product Code: 1-22460	ao. Univ. Prof. Dr. Elisabeth Aberer	NULL	Not Recruiting			Female: yes Male: yes		Phase 4	Austria
8	EUCTR2004-002712-28-IT (EUCTR)	28/02/2005	15/02/2006	Chronic iloprostadministration in scleroderma patients effect on disease progression, as assessed by ...	Chronic iloprostadministration in scleroderma patients effect on disease progression, as assessed by ...	Disease progression in scleroderma. MedDRA version: 6.1;Level: HLT;Classification code 10039711	Trade Name: ENDOPROST 0,05MG/0,5ML 1F INN or Proposed INN: iloprost trometamol	ITALFARMACO	NULL	Not Recruiting			Female: yes Male: yes	69	Phase 3	Italy
9	NCT00622687 (ClinicalTrials.gov)	September 1997	14/2/2008	Effect of Different Iloprost Doses on Symptoms in Systemic Sclerosis	Comparision Between Maximally Tolerated Intravenous IloprostDoses Versus Low-Dosed Iloprostfor a 21- ...	Systemic Sclerosis	Drug: iloprost;Drug: iloprost low dose;Drug: iloprost therapy up to 2 ng/kg x min	Charite University, Berlin, Germany	Schering-Plough	Terminated	18 Years	80 Years	Both	50	Phase 2	Germany
10	NCT00004786 (ClinicalTrials.gov)	December 1995	24/2/2000	Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Iloprostfor Raynaud's Phenomeno ...		Systemic Sclerosis;Raynaud Disease	Drug: iloprost	National Center for Research Resources (NCRR)	University of Pittsburgh	Completed	18 Years	N/A	Both	200	Phase 3	NULL

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84. サルコイドーシス

臨床試験数 : 149 / 薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00403650 (ClinicalTrials.gov)	November 2006	24/11/2006	Inhaled Iloprost for Sarcoidosis-associated Pulmonary Hypertension	Inhaled Iloprost for Sarcoidosis Associated Pulmonary Hypertension	Sarcoidosis;Pulmonary Arterial Hypertension	Drug: Iloprost	University of Cincinnati	NULL	Completed	18 Years	90 Years	Both	20	Phase 4	United States

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85. 特発性間質性肺炎

臨床試験数 : 627 / 薬物数 : 443 - (DrugBank : 120) / 標的遺伝子数 : 99 - 標的パスウェイ数 : 212

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00109681 (ClinicalTrials.gov)	April 2005	2/5/2005	Inhaled Iloprostin Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary ...	A Randomized, Double-blind, Placebo-Controlled Phase II Study to Evaluate the Safety and Pilot Effic ...	Pulmonary Fibrosis;Pulmonary Hypertension	Drug: Iloprost Inhalation Solution (Ventavis)	Actelion	NULL	Completed	40 Years	85 Years	Both	50	Phase 2	United States

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86. 肺動脈性肺高血圧症

臨床試験数 : 1,205 / 薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03293407 (ClinicalTrials.gov)	February 1, 2018	20/9/2017	Evaluation of Inhaled IloprostEffects Using the Breelib Nebulizer, on Clinical Outcomes and Physical ...	Ventavis® (Iloprost): Evaluation of Inhaled IloprostEffects Using the Breelib™ Nebulizer, on Clinica ...	Hypertension, Pulmonary	Drug: Iloprost (Ventavis, BAYQ6256);Device: Breelib nebulizer	Bayer	NULL	Completed	18 Years	N/A	All	31		Germany
2	JPRN-UMIN000027284	2017/07/01	01/07/2017	The effect of iloprost on pulmonary hypertension and exercuse capacity	The effect of iloproston pulmonary hypertension and exercuse capacity - Iloprostfor Pulmonary Hypert ...	Pulmonary arterial hypertension	inhale of iloprost	The University of Tokushima Graduate School of Health Biosciences	NULL	Pending	20years-old	90years-old	Male and Female	20	Not selected	Japan
3	NCT03365479 (ClinicalTrials.gov)	May 1, 2017	27/11/2017	Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension	Acute Hemodynamic Response of IloprostInhalation Using the Breelib Nebulizer in Pulmonary Arterial H ...	Pulmonary Hypertension;Pulmonary Arterial Hypertension	Drug: Iloprost	University of Giessen	NULL	Completed	18 Years	N/A	All	30	N/A	Germany
4	NCT02826252 (ClinicalTrials.gov)	September 15, 2016	5/7/2016	Examination of Ventavis (Iloprost) Inhalation Behavior Using the I-Neb AAD System in Patients With P ...	VENTASWITCH, Examination of Ventavis® (Iloprost) Inhalation Behavior Using the I-Neb® AAD® System in ...	Hypertension, Pulmonary	Drug: Iloprost,(Ventavis, BAYQ6256);Device: I-Neb AAD system	Bayer	NULL	Completed	18 Years	N/A	All	64	N/A	Germany
5	NCT02825160 (ClinicalTrials.gov)	August 1, 2016	15/6/2016	Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension ( ...	Drug Use Investigation of Ventavis for Pulmonary Arterial Hypertension (PAH)	Hypertension, Pulmonary	Drug: Ventavis (Iloprost, BAYQ6256)	Bayer	NULL	Recruiting	N/A	N/A	All	270		Japan
6	EUCTR2014-000091-25-GB (EUCTR)	01/09/2014	11/07/2014	A single-centre, placebo-controlled, double-blinded, randomized, cross-over study of Iloprost(Ventav ...	A single-centre, placebo-controlled, double-blinded, randomized, cross-over study of Iloprost(Ventav ...	Pulmonary Arterial Hypertension Eisenmenger syndrome MedDRA version: 17.0;Level: LLT;Classification ...	Trade Name: Iloprost Product Name: Ventavis INN or Proposed INN: Iloprost	Royal Brompton and Harefield NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes	15	Phase 4	United Kingdom
7	NCT02032836 (ClinicalTrials.gov)	March 10, 2014	9/1/2014	Comparative PK PD Study in PAH Patients (Fox vs. I-Neb)	A Multi-center, Open-label, Randomized Cross-over Study to Compare the Acute Tolerability and Pharma ...	Pulmonary Arterial Hypertension	Drug: lloprost(Ventavis,BAYQ6252, 20 µg/mL);Drug: lloprost(Ventavis,BAYQ6252, 10 µg/mL)	Bayer	NULL	Completed	18 Years	N/A	All	27	Phase 1/Phase 2	Austria;Germany
8	EUCTR2013-002783-12-DE (EUCTR)	07/01/2014	18/09/2013	No	A multi-center, open-label, randomized cross-over study to compare the acute tolerability and pharma ...	Patients with Pulmonary arterial hypertension, WHO class III, who have been on therpay with Ventavis ...	Trade Name: Ventavis 10 Product Name: Ventavis 10 Product Code: Bay Q 6256 INN or Proposed INN: ILOPROS ...	Bayer HealthCare AG	NULL	Not Recruiting			Female: yes Male: yes	24	Phase 1;Phase 2	Austria;Germany
9	EUCTR2013-002783-12-AT (EUCTR)	02/12/2013	18/10/2013	No	A multi-center, open-label, randomized cross-over study to compare the acute tolerability and pharma ...	Patients with Pulmonary arterial hypertension, WHO class III, who have been on therpay with Ventavis ...	Trade Name: Ventavis 10 Product Name: Ventavis 10 Product Code: Bay Q 6256 INN or Proposed INN: ILOPROS ...	Bayer AG	NULL	Not Recruiting			Female: yes Male: yes	24	Phase 1;Phase 2	Austria;Germany
10	NCT01894035 (ClinicalTrials.gov)	September 23, 2013	3/7/2013	Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hype ...	Study to Assess the Compliance of Patients With Pulmonary Arterial Hypertension Treated With Inhaled ...	Pulmonary Hypertension	Drug: Iloprost (Ventavis, BAYQ 6256)	Bayer	NULL	Completed	18 Years	N/A	All	13		Portugal

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