Antithymocyte Globulin ( DrugBank: - )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
60	再生不良性貧血	28
284	ダイアモンド・ブラックファン貧血	2

60. 再生不良性貧血

臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05323617 (ClinicalTrials.gov)	May 15, 2023	5/4/2022	Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Imm ...	Two Arm Bridging Study to Evaluate the Efficacy of Romiplostim in the Treatment of Adult Severe Apla ...	Severe Aplastic Anemia (SAA)	Drug: Romiplostim;Drug: Antithymocyte Globulin;Drug: Cyclosporine A	Amgen	NULL	Not yet recruiting	18 Years	N/A	All	40	Phase 2	NULL
2	NCT05049668 (ClinicalTrials.gov)	October 2021	13/9/2021	RACE 2: a Long Term Follow-up of Patients Participating in the RACE Trial	Long-term Follow-up of Patients Participating in RACE: the Prospective Randomized Multicenter Study ...	Severe Aplastic Anemia	Drug: ATGAM plus CsA with or without Eltrombopag	European Society for Blood and Marrow Transplantation	NULL	Enrolling by invitation	N/A	N/A	All	197		France
3	NCT03531736 (ClinicalTrials.gov)	May 9, 2018	9/5/2018	T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intens ...	Allogeneic Hematopoietic Stem Cell Transplantation of a/ß T-Lymphocyte Depleted Graft Conditioned Wi ...	Myeloid Diseases	Drug: Antithymocyte globulin(Rabbit);Drug: fludarabine;Radiation: total body irradiation;Drug: cyclo ...	Memorial Sloan Kettering Cancer Center	NULL	Recruiting	18 Years	N/A	All	15	Phase 1	United States
4	NCT03318159 (ClinicalTrials.gov)	April 20, 2018	10/10/2017	Posaconazole Prophylaxis During ATG Treatment for hMDS/AA Patients	Open Label, Phase II Study Investigating the Efficacy of Posaconazole as Prophylaxis Antifungal Agen ...	Aplastic Anemia;Myelodysplastic Syndromes;Fungal Infection	Drug: Posaconazole	Seoul National University Hospital	Merck Sharp & Dohme Corp.	Unknown status	18 Years	75 Years	All	40	Phase 2	Korea, Republic of
5	NCT02918292 (ClinicalTrials.gov)	July 3, 2017	27/9/2016	Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)	Optimizing Haploidentical Aplastic Anemia Transplantation (CHAMP) (BMT CTN 1502)	Severe Aplastic Anemia	Drug: Antithymocyte Globulin(ATG);Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total Body Irr ...	Medical College of Wisconsin	National Heart, Lung, and Blood Institute (NHLBI);National Cancer Institute (NCI);Blood and Marrow T ...	Completed	N/A	75 Years	All	32	Phase 2	United States
6	EUCTR2014-000363-40-NL (EUCTR)	07/01/2016	01/09/2015	A trial in which will be studied if the addition of a medicine that is used for improving platelet c ...	A prospective Randomized multicenter study comparing horse Antithymocyte globuline (hATG) + Cyclospo ...	Idiopathic (Severe) Aplastic Anemia, a bone marrow failure syndrome which results in the normal hema ...	Trade Name: REVOLADE INN or Proposed INN: ELTROMBOPAG	European Society for Blood and Marrow Transplantation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	200	Phase 3	Spain;Netherlands
7	EUCTR2014-000363-40-ES (EUCTR)	26/10/2015	07/09/2015	A trial in which will be studied if the addition of a medicine that is used for improving platelet c ...	A prospective Randomized multicenter study comparing horse Antithymocyte globuline (hATG) + Cyclospo ...	Idiopathic (Severe) Aplastic Anemia, a bone marrow failure syndrome which results in the normal hema ...	Trade Name: Revolade INN or Proposed INN: ELTROMBOPAG	European Society for Blood and Marrow Transplantation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	200		Spain
8	NCT02099747 (ClinicalTrials.gov)	July 2015	6/3/2014	hATG+CsA vs hATG+CsA+Eltrombopag for SAA	A Prospective Randomized Multicenter Study Comparing Horse Antithymocyte Globuline (hATG) + Cyclospo ...	Severe Aplastic Anemia	Drug: hATG;Drug: CsA;Drug: Eltrombopag	European Group for Blood and Marrow Transplantation	Novartis;Pfizer	Active, not recruiting	15 Years	N/A	All	202	Phase 3	France;Italy;Netherlands;Spain;Switzerland;United Kingdom;Germany
9	NCT01844635 (ClinicalTrials.gov)	May 2012	29/4/2013	Randomised Study Comparing Different Dosages of Rabbit ATG in Patients With SAA	A Prospective Randomized Multicenter Study Comparing Different Dosages of Rabbit Antithymocyte Globu ...	Acquired Aplastic Anemia.	Drug: Thymoglobulin	Nagoya University	NULL	Recruiting	N/A	69 Years	Both	320	Phase 3	Japan
10	EUCTR2007-000902-55-DE (EUCTR)	17/12/2009	29/09/2009	Prospective Phase II Pilot study of Rabbit Antithymocyte globulin(ATG, Thymoglobuline®, Genzyme) wit ...	Prospective Phase II Pilot study of Rabbit Antithymocyte globulin(ATG, Thymoglobuline®, Genzyme) wit ...	Acquired severe aplastic anaemia and transfusion dependent non-severe aplastic anaemia MedDRA versio ...	Trade Name: Thymoglobulin Product Name: Thymoglobuline®/Thymoglobulin® Product Code: anti-thymocyte gl ...	EBMT (European Group for Blood and Marrow Transplantation)	NULL	Not Recruiting			Female: yes Male: yes	35	Phase 2	France;Germany;United Kingdom

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284. ダイアモンド・ブラックファン貧血

臨床試験数 : 36 / 薬物数 : 95 - (DrugBank : 34) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 126

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00305708 (ClinicalTrials.gov)	August 2000	21/3/2006	Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treati ...	Bone Marrow Stem Cell Transplantation for Children With Stem Cell Defects, Marrow Failure Syndromes, ...	Congenital Amegakaryocytic Thrombocytopenia;Diamond-blackfan Anemia;Fanconi Anemia;Leukemia;Severe C ...	Biological: anti-thymocyte globulin;Drug: busulfan;Drug: fludarabine phosphate;Procedure: allogeneic ...	University of California, San Francisco	National Cancer Institute (NCI)	Completed	N/A	17 Years	Both	40	Phase 1/Phase 2	United States
2	NCT00001749 (ClinicalTrials.gov)	July 1998	3/11/1999	Medical Treatment for Diamond Blackfan Anemia	Treatment of Diamond Blackfan Anemia With Antithymocyte Globulin and Cyclosporine A	Fanconi's Anemia;Hematologic Disease	Drug: Antithymocyte globulin;Drug: Cyclosporine	National Heart, Lung, and Blood Institute (NHLBI)	NULL	Completed	N/A	N/A	Both	25	Phase 2	United States

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