DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
Bryostatin 1 ( DrugBank:
Bryostatin 1
)
1 disease
告示番号
疾患名
（ページ内リンク）
臨床試験数
62
発作性夜間ヘモグロビン尿症
1
62. 発作性夜間ヘモグロビン尿症
臨床試験数
:
292
/
薬物数
:
151
- (
DrugBank
:
49
) /
標的遺伝子数
:
22
-
標的パスウェイ数
:
108
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No.
TrialID
Date_
enrollment
Date_
registration
Public_title
Scientific_title
Condition
Intervention
Primary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
Phase
Countries
1
NCT00012376
(
ClinicalTrials.gov
)
March 2001
3/3/2001
Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer
Dose Finding Study of Bryostatin-1 and GM-CSF in Refractory Myeloid Malignancies
Accelerated Phase Chronic Myelogenous Leukemia;Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;Adult Acute Myeloid Leukemia With Del(5q);Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);Adult Acute Myeloid Leukemia With t(16;16)(p13;Adult Acute Myeloid Leukemia With t(8;21)(q22;Blastic Phase Chronic Myelogenous Leukemia;Chronic Myelomonocytic Leukemia;Chronic Phase Chronic Myelogenous Leukemia;Paroxysmal Nocturnal Hemoglobinuria;Previously Treated Myelodysplastic Syndromes;Recurrent Adult Acute Myeloid Leukemia;Refractory Anemia;Refractory Anemia With Ringed Sideroblasts;Relapsing Chronic Myelogenous Leukemia;Thrombocytopenia;Untreated Adult Acute Myeloid Leukemia
Accelerated Phase Chronic Myelogenous Leukemia;Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnorma ...
Drug:
bryostatin 1
;Biological: sargramostim;Other: laboratory biomarker analysis;Other: pharmacological study
Drug:
bryostatin 1
;Biological: sargramostim;Other: laboratory biomarker analysis;Other: pharmacologi ...
National Cancer Institute (NCI)
NULL
Completed
18 Years
N/A
Both
35
Phase 1
United States