TPO ( DrugBank: - )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
63特発性血小板減少性紫斑病6

63. 特発性血小板減少性紫斑病


臨床試験数 : 391 薬物数 : 235 - (DrugBank : 50) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 139
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PhaseCountries
1NCT05718856
(ClinicalTrials.gov)
April 1, 202313/11/2022TPO-RAs Combining Anti-CD 20 Monoclonal Antibody Versus TPO-RAs in the Management of Pediatric Primary Immune Thrombocytopenia (ITP)A Multicenter, Randomized, Open-label StudyTo Compare The Efficacy And Safety Of TPO-RAs Combining Anti-CD 20 Monoclonal Antibody Versus TPO-RAs in Persistent or Chronic Pediatric ITP Patients Who Failed or Relapse After Hormone TherapyPrimary Immune Thrombocytopenia (ITP)Drug: TPO-RAs;Drug: TPO-RAs combining anti-CD 20 monoclonal antibodyInstitute of Hematology & Blood Diseases HospitalBeijing Children's Hospital;Tianjin People's Hospital;The Second Affiliated Hospital of Kunming Medical University;Henan Cancer Hospital;Tianjin Medical University Second Hospital;The First Affiliated Hospital of Xiamen UniversityNot yet recruiting6 Years17 YearsAll166Phase 4China
2NCT04890041
(ClinicalTrials.gov)
May 30, 202112/5/2021TPO-RA in Primary Immune Thrombocytopenia (ITP) in Patients Older Than 14 YearsEfficacy of TPO-RA in the Management of Primary Immune Thrombocytopenia (ITP) in Patients Older Than 14 Years With Poor First-line Response: a Multi-center, Prospective, One-arm StudyPrimary Immune Thrombocytopenic PurpuraDrug: TPO-RAInstitute of Hematology & Blood Diseases HospitalNULLRecruiting14 YearsN/AAll100N/AChina
3ChiCTR2000039630
2021-01-012020-11-03Phase II clinical trial of the superiority of montelukastine in combination with TPO-MPL agonists for the treament of primary immune thrombocytopeniaPhase II clinical trial of the superiority of montelukastine in combination with TPO-MPL agonists for the treament of primary immune thrombocytopenia Primary immune thrombocytopeniaexperimental group:Montelukast sodium 10mg/day; rhTPO 15000 units;control group:rhTPO 15000 units;Department of Hematology, Second Medical Center, Chinese PLA General HospitalNULLRecruiting1480Bothexperimental group:51;control group:51;Phase 2China
4NCT04214951
(ClinicalTrials.gov)
January 1, 202028/12/2019A Study of Eltrombopag and Recombinant Human Thrombopoietin In Primary Immune ThrombocytopeniaA Prospective Observational Study of Switching Eltrombopag and Recombinant Human Thrombopoietin In Primary Immune ThrombocytopeniaCorticosteroid-resistant or Relapsed ITPDrug: Eltrombopag;Drug: Recombinant human thrombopoietin (rh-TPO)Peking University People's HospitalNULLActive, not recruiting18 Years75 YearsAll100China
5NCT04089267
(ClinicalTrials.gov)
December 201610/9/2019Evaluating the Efficacy and Safety of Different Human Thrombopoietin (rhTPO) Regimens in the Treatment of Patients With Primary Immune Thrombocytopenia (ITP)Multicenter, Randomized, Open, Parallel Controlled Trials Evaluating the Efficacy and Safety of Different Human Thrombopoietin (rhTPO) Regimens in the Treatment of Patients With Primary Immune Thrombocytopenia (ITP)ITPDrug: TPOShenyang Sunshine Pharmaceutical Co., LTD.NULLCompleted18 YearsN/AAll288Phase 4China
6NCT01506414
(ClinicalTrials.gov)
June 200916/11/2011Recombinant Human Thrombopoietin in Combination With Rituximab in Immune Thrombocytopenia (ITP)A Multicentre Investigation of Recombinant Human Thrombopoietin (Rh-TPO) Combine With Low-dose Rituximab in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia (ITP)Purpura;Idiopathic Thrombocytopenic PurpuraDrug: rhTPO in combination with RituximabMing HouPeking Union Medical College Hospital;Chinese Academy of Medical Sciences;First Affiliated Hospital, Sun Yat-Sen University;West China Hospital;Shandong Provincial Hospital;Wuhan Union Hospital, China;Zhejiang UniversityCompleted16 Years75 YearsBoth91Phase 3China