Fecal Microbial Transplantation ( DrugBank: - )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
96	クローン病	4
97	潰瘍性大腸炎	3

96. クローン病

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03267238 (ClinicalTrials.gov)	June 16, 2017	24/7/2017	Fecal Microbial Transplantation in Patients With Crohn's Disease	Fecal Microbial Transplantation in Patients With Crohn's Disease	Crohn Disease	Biological: Fecal Microbial Transplantation	Stony Brook University	NULL	Completed	7 Years	N/A	All	9	Early Phase 1	United States
2	JPRN-jRCTs031180415	01/02/2017	22/03/2019	A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	Single center non-randomized study: A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease) Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)	AFM therapy arm : three antibiotics, amoxicillin (1500 mg/day), fosfomycin (3000 mg/day) and metronidazole (750 mg/day) are administered orally to patients for 2 weeks. For pediatric patients, amoxicillin (50mg/kg), fosfomycin (120mg/kg) and metronidazole (20mg/kg) are administered orally for 2 weeks (the upper limit is the same amount as adults). FMT arm : Approximately 150 to 250 g of donor stool is diluted with saline (500 mL) and filtered to remove crude components. The diluted and filtered fecal suspension is transferred into the patients colon from cecum to rectum during total colonoscopy. As usual examinations, the patient undergoes biopsy of inflammatory site. A-FMT arm : Patient undergoes FMT two days after AFM therapy.	Ishikawa Dai	NULL	Recruiting	>= 6age old	Not applicable	Both	120	N/A	Japan
3	JPRN-UMIN000025846	2017/02/01	01/02/2017	A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease - A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	ulcerative colitis, Crohn's disease	Administration of the fecal material from healthy donors to patients after taking three kinds of antibiotics (Amoxicillin, fosmycin, metronidazole) for two weeks	Juntendo university school of medicineDepartment of gastroenterology	NULL	Recruiting	16years-old	Not applicable	Male and Female	60	Not selected	Japan
4	NCT01847170 (ClinicalTrials.gov)	May 2013	2/5/2013	Impact of Fecal Biotherapy (FBT) on Microbial Diversity in Patients With Moderate to Severe Inflammatory Bowel Disease		Crohn's Disease	Biological: Fecal Microbial Transplantation	Beth Israel Deaconess Medical Center	The Broad Foundation;Brigham and Women's Hospital	Completed	18 Years	N/A	All	22	Phase 1	United States

97. 潰瘍性大腸炎

臨床試験数 : 2,630 / 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCTs031180415	01/02/2017	22/03/2019	A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	Single center non-randomized study: A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease) Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)	AFM therapy arm : three antibiotics, amoxicillin (1500 mg/day), fosfomycin (3000 mg/day) and metronidazole (750 mg/day) are administered orally to patients for 2 weeks. For pediatric patients, amoxicillin (50mg/kg), fosfomycin (120mg/kg) and metronidazole (20mg/kg) are administered orally for 2 weeks (the upper limit is the same amount as adults). FMT arm : Approximately 150 to 250 g of donor stool is diluted with saline (500 mL) and filtered to remove crude components. The diluted and filtered fecal suspension is transferred into the patients colon from cecum to rectum during total colonoscopy. As usual examinations, the patient undergoes biopsy of inflammatory site. A-FMT arm : Patient undergoes FMT two days after AFM therapy.	Ishikawa Dai	NULL	Recruiting	>= 6age old	Not applicable	Both	120	N/A	Japan
2	JPRN-UMIN000025846	2017/02/01	01/02/2017	A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease - A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease	ulcerative colitis, Crohn's disease	Administration of the fecal material from healthy donors to patients after taking three kinds of antibiotics (Amoxicillin, fosmycin, metronidazole) for two weeks	Juntendo university school of medicineDepartment of gastroenterology	NULL	Recruiting	16years-old	Not applicable	Male and Female	60	Not selected	Japan
3	NCT03268213 (ClinicalTrials.gov)	November 2013	22/3/2016	Fecal Microbial Transplantation for C. Difficile and/or Ulcerative Colitis or Indeterminate Colitis	Fecal Microbial Transplantation in Patients With Medication Refractory Clostridium Difficile and/or Ulcerative Colitis or Indeterminate Colitis	Clostridium Difficile Infection;Ulcerative Colitis;Indeterminate Colitis	Biological: Fecal Microbial Transplantation	Stony Brook University	NULL	Completed	7 Years	N/A	All	12	Early Phase 1	United States