ANDROGRAPHIS PANICULATA ( DrugBank: - )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
97潰瘍性大腸炎12

97. 潰瘍性大腸炎


臨床試験数 : 2,630 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1EUCTR2013-003060-31-BG
(EUCTR)
18/06/201410/04/2014A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects with Mild to Moderate Ulcerative Colitis with Clinical Remission or Response from Induction Therapy. (NATRUL-4) Ulcerative Colitis (UC)
MedDRA version: 17.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
460Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia
2EUCTR2013-003060-31-PL
(EUCTR)
11/06/201419/03/2014A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects with Mild to Moderate Ulcerative Colitis with Clinical Remission or Response from Induction Therapy. (NATRUL-4) Ulcerative Colitis (UC)
MedDRA version: 16.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
460Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia
3EUCTR2013-003060-31-CZ
(EUCTR)
10/04/201404/02/2014A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects with Mild to Moderate Ulcerative Colitis with Clinical Remission or Response from Induction Therapy.(NATRUL-4) Ulcerative Colitis (UC)
MedDRA version: 16.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
460Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia
4EUCTR2013-003060-31-HU
(EUCTR)
02/04/201431/01/2014A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects with Mild to Moderate Ulcerative Colitis with Clinical Remission or Response from Induction Therapy. (NATRUL-4) Ulcerative Colitis (UC)
MedDRA version: 17.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
460Phase 3United States;Czech Republic;Hungary;Poland;Ukraine;Lithuania;Bulgaria;Latvia
5EUCTR2013-003060-31-LV
(EUCTR)
17/02/201416/12/2013A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects with Mild to Moderate Ulcerative Colitis with Clinical Remission or Response from Induction Therapy. (NATRUL-4) Ulcerative Colitis (UC)
MedDRA version: 17.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
460Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia
6EUCTR2013-003060-31-LT
(EUCTR)
11/02/201430/12/2013A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects with Mild to Moderate Ulcerative Colitis with Clinical Remission or Response from Induction Therapy. (NATRUL-4) Ulcerative Colitis (UC)
MedDRA version: 16.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
460Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia
7EUCTR2013-002116-27-BG
(EUCTR)
19/12/201316/10/2013A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III, Randomized, Multi-Centre, Double-Blind,Placebo-Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative Colitis (NATRUL-3) Ulcerative Colitis (UC)
MedDRA version: 17.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
420Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia
8EUCTR2013-002116-27-LT
(EUCTR)
14/11/201306/08/2013A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III, Randomized, Multi-Centre, Double-Blind,Placebo-Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative Colitis (NATRUL-3) Ulcerative Colitis (UC)
MedDRA version: 16.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
420Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia;Korea, Republic of
9EUCTR2013-002116-27-LV
(EUCTR)
28/10/201326/06/2013A Placebo Controlled Trial of HMPL-004 in Patients with Mild to Moderate Active Ulcerative ColitisA Phase III, Randomized, Multi-Centre, Double-Blind,Placebo-Controlled Trial of HMPL-004 in Patients with Mild to Moderate Active Ulcerative Colitis (NATRUL-3) Ulcerative Colitis (UC)
MedDRA version: 17.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
420Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia;Korea, Republic of
10EUCTR2013-002116-27-HU
(EUCTR)
24/10/201324/07/2013A Placebo Controlled Trial of HMPL-004 in Patients with Mild to Moderate Active Ulcerative ColitisA Phase III, Randomized, Multi-Centre, Double-Blind,Placebo-Controlled Trial of HMPL-004 in Patients with Mild to Moderate Active Ulcerative Colitis (NATRUL-3) Ulcerative Colitis (UC)
MedDRA version: 17.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
420Phase 3United States;Czech Republic;Hungary;Poland;Ukraine;Lithuania;Bulgaria;Latvia;Korea, Republic of
11EUCTR2013-002116-27-CZ
(EUCTR)
09/10/201308/08/2013A Placebo Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative ColitisA Phase III, Randomized, Multi-Centre, Double-Blind,Placebo-Controlled Trial of HMPL-004 in Subjects with Mild to Moderate Active Ulcerative Colitis (NATRUL-3) Ulcerative Colitis (UC)
MedDRA version: 16.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Product Code: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA
Other descriptive name: AND (Andrographolide)
Other descriptive name: NAND (Neoandrographolide)
Other descriptive name: DAND (14-Deoxyandrographolide)
Other descriptive name: DDAND (14-deoxy-11,12-didehydroandrographolide)
Other descriptive name: CLA (Chlorogenic acid)
Other descriptive name: AODG (Apigenin-7-O-glucuronide)
Nutrition Science Partners LimitedNULLNot RecruitingFemale: yes
Male: yes
420Phase 3United States;Hungary;Czech Republic;Poland;Ukraine;Lithuania;Bulgaria;Latvia;Korea, Republic of
12EUCTR2007-005166-12-DE
(EUCTR)
29/07/200815/01/2008A Phase II, Randomized, Multi-Centre, Double-Blind, Placebo-Controlled Trial of HMPL-004 in Patients with Mild to Moderate Active Ulcerative Colitis with or without MesalamineA Phase II, Randomized, Multi-Centre, Double-Blind, Placebo-Controlled Trial of HMPL-004 in Patients with Mild to Moderate Active Ulcerative Colitis with or without Mesalamine active mild to moderate ulcerative colitis defined as a Mayo clinical score of 4-10 points
MedDRA version: 9.1;Level: LLT;Classification code 10066678;Term: Acute ulcerative colitis
Product Name: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA (ethanol extract)
Product Name: HMPL-004
Other descriptive name: ANDROGRAPHIS PANICULATA (ethanol extract)
Hutchison MediPharma Enterprises LimitedNULLNot RecruitingFemale: yes
Male: yes
210Phase 2Germany