Serotonin ( DrugBank: Serotonin )

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1 disease

ID	Disease name (Link within this page)	Number of trials
2	Amyotrophic lateral sclerosis	2

2. Amyotrophic lateral sclerosis

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Clinical trials : 645 /  Drugs : 589 - (DrugBank : 163) / Drug target genes : 150 - Drug target pathways : 225

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02851914 (ClinicalTrials.gov)	July 21, 2015	28/7/2016	SSRIs vs. TCAs for Depression in ALS Patients	An Open-Label Pilot Study Comparing the Efficacy of Selective Serotonin Re-Uptake Inhibitors (SSRIs) Versus Tricyclic Antidepressants (TCAs) for Treating Depression in Amyotrophic Lateral Sclerosis	Depression;Amyotrophic Lateral Sclerosis	Drug: Tricyclic Antidepressants (TCA);Drug: Selective Serotonin Uptake Inhibitors (SSRI)	St. Louis University	NULL	Completed	25 Years	80 Years	All	2	Early Phase 1	United States
2	NCT01160263 (ClinicalTrials.gov)	October 2012	9/7/2010	Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls	Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls. Analysis With 123I-FP-CIT (Datscan) and 123I-ADAM Brain SPECT	Amyotrophic Lateral Sclerosis	Drug: SPECT : 123 I-FP-CIT (DATSCAN) and 123I-ADAM	Assistance Publique - Hôpitaux de Paris	Association Française contre les Myopathies (AFM), Paris;ARS (Association pour la Recherche sur la Sclérose Latérale Amyotrophique);AGEPS	Completed	39 Years	66 Years	Both	16	Phase 3	France