Grapefruit ( DrugBank: Grapefruit )

5 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	1
46	Malignant rheumatoid arthritis	1
50	Dermatomyositis	1
83	Addison disease	1
97	Ulcerative colitis	1

6. Parkinson disease

Clinical trials : 2,307 / Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000021236	2016/03/01	01/03/2016	Investigation in effect of aroma therapy using magnetoencepharography	Investigation in effect of aroma therapy using magnetoencepharography - Aroma with MEG	Normal volunteer, Epilepsy patients, Parkinson disease patients	aroma 1 Trans-nasal administration of lavender essence Subject hold a cup with 0.05ml essence in front of the nose for 2 minutes After the administration, MEG signals will be recorded for 4 minutes Also, the subjects were evaluated their moods and awareness. aroma 2 Trans-nasal administration of grapefruit essence Subject hold a cup with 0.05ml essence in front of the nose for 2 minutes After the administration, MEG signals will be recorded for 4 minutes Also, the subjects were evaluated their moods and awareness. fragrant Trans-nasal administration of fragrant Subject hold a cup with 0.05ml essence in front of the nose for 2 minutes After the administration, MEG signals will be recorded for 4 minutes Also, the subjects were evaluated their moods and awareness.	Osaka University Graduate School of Medicine Department of Neurosurgery	NULL	Complete: follow-up continuing	20years-old	80years-old	Male and Female	10	Phase 1	Japan

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus - Effect of grapefruit juice with Tacrolimus	rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulcerative colitis	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan

Clinical trials : 194 / Drugs : 244 - (DrugBank : 89) / Drug target genes : 50 - Drug target pathways : 151

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus - Effect of grapefruit juice with Tacrolimus	rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulcerative colitis	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan

Clinical trials : 20 / Drugs : 39 - (DrugBank : 13) / Drug target genes : 6 - Drug target pathways : 18

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01271296 (ClinicalTrials.gov)	April 2008	22/12/2010	Effects and Interactions of Liquorice and Grapefruit on Glucocorticoid Replacement Therapy in Addison's Disease	Use of Liquorice and Grapefruit in Patients With Addison's Disease	Addison Disease	Dietary Supplement: Liquorice;Dietary Supplement: Grapefruit Juice	Haukeland University Hospital	NULL	Completed	18 Years	80 Years	Both	17	N/A	Norway

Clinical trials : 2,630 / Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus - Effect of grapefruit juice with Tacrolimus	rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulcerative colitis	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan