Anti-Thymocyte Globulin ( DrugBank: - )

1 disease

ID	Disease name (Link within this page)	Number of trials
60	Aplastic anemia	34

60. Aplastic anemia

Clinical trials : 245 / Drugs : 318 - (DrugBank : 86) / Drug target genes : 44 - Drug target pathways : 166

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05600426 (ClinicalTrials.gov)	January 25, 2023	20/10/2022	A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Ap ...	A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation With Immune Suppr ...	Severe Aplastic Anemia	Drug: cyclosporine;Procedure: Matched Unrelated Donor Hematopoetic Stem Cell Transplant;Drug: horse ...	Boston Children's Hospital	Center for International Blood and Marrow Transplant Research;National Institutes of Health (NIH);Na ...	Recruiting	0 Years	25 Years	All	234	Phase 3	United States
2	ChiCTR2100045322	2021-06-01	2021-04-12	Efficacy and safety of umbilical cord mesenchymal stem cells combined with standard immunosuppressiv ...	Efficacy and safety of umbilical cord mesenchymal stem cells combined with standard immunosuppressiv ...	pediatric acquired severe aplastic anemia	Experimental group:Anti-thymocyte globulin+Ciclosporin A+Mesenchymal stem cell;Control group:Anti-th ...	Institute of Hematology & Blood Disease Hospital Chinese Academy of Medical Sciences	NULL	Recruiting	1	16	Both	Experimental group:32;Control group:32;		China
3	NCT04328727 (ClinicalTrials.gov)	November 4, 2020	9/3/2020	Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplasti ...	A Non-randomized, Open Label, Multi-center, Phase II Study to Assess the Safety and Efficacy of Eltr ...	Severe Aplastic Anemia (SAA)	Drug: eltrombopag;Drug: rabbit anti-thymocyte globulin (r-ATG);Drug: cyclosporine A (CsA)	Novartis Pharmaceuticals	NULL	Active, not recruiting	6 Years	N/A	All	36	Phase 2	China;Japan;Korea, Republic of;Taiwan
4	NCT03622788 (ClinicalTrials.gov)	August 8, 2019	3/8/2018	Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell T ...	Anti-Viral Central Memory CD8 Veto Cells in Haploidentical Hematopoietic Stem Cell Transplantation	Follicular Lymphoma;Hodgkin Lymphoma;Mantle Cell Lymphoma;Myelodysplastic Syndrome;Myeloproliferativ ...	Biological: Anti-Thymocyte Globulin;Drug: Cyclophosphamide;Biological: Cytokine-treated Veto Cells;D ...	M.D. Anderson Cancer Center	NULL	Recruiting	12 Years	75 Years	All	24	Phase 1/Phase 2	United States
5	NCT02845596 (ClinicalTrials.gov)	August 2016	9/5/2016	Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia	Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia	Severe Aplastic Anemia	Drug: cyclosporine;Procedure: Matched Unrelated Donor Hematopoietic Stem Cell Transplant;Drug: horse ...	Michael Pulsipher, MD	NULL	Active, not recruiting	N/A	25 Years	All	40	N/A	United States
6	NCT02462252 (ClinicalTrials.gov)	October 2015	25/5/2015	Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclospori ...	A Phase IIA, Open-label Study Designed to Evaluate Efficacy and Safety of BL-8040 Followed by Anti-T ...	Aplastic Anemia;Hypoplastic Myelodysplastic Syndrome	Drug: BL-8040;Drug: horse anti-thymocyte globulin (hATG);Drug: Methylprednisolone;Drug: Cyclosporine	BioLineRx, Ltd.	NULL	Recruiting	18 Years	N/A	All	25	Phase 2	United States
7	NCT02404025 (ClinicalTrials.gov)	May 12, 2015	26/2/2015	Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A in Naive Aplastic Anem ...	A Non-randomized, Phase II Study of Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/C ...	Aplastic Anemia	Drug: Eltrombopag;Drug: Rabbit ATG;Drug: CsA	Novartis Pharmaceuticals	NULL	Completed	18 Years	75 Years	All	10	Phase 2	Japan
8	NCT02162420 (ClinicalTrials.gov)	January 10, 2015	10/6/2014	Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia	Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia	Dyskeratosis Congenita;Aplastic Anemia	Drug: Alemtuzumab;Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total Body Irradiation;Biologi ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	0 Years	70 Years	All	50	N/A	United States
9	NCT01759732 (ClinicalTrials.gov)	September 2012	30/12/2012	Haploidentical Stem Cell Transplantation for Children With Acquired Severe Aplastic Anemia	Haploidentical Stem Cell Transplantation With Fixed Dose of T Cells After in Vitro T Cell Depletion ...	Acquired Aplastic Anemia	Drug: Fludarabine;Drug: Cyclophosphamide;Biological: anti-thymocyte globulin;Biological: filgrastim; ...	Asan Medical Center	NULL	Recruiting	N/A	21 Years	Both	10	Phase 2	Korea, Republic of
10	NCT01624805 (ClinicalTrials.gov)	June 25, 2012	19/6/2012	Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or ...	Phase II Study of Horse Anti-Thymocyte Globulin(hATG), Cyclosporine, Methylprednisolone, and GCSF (F ...	Aplastic Anemia;de Novo Myelodysplastic Syndrome;Myelodysplastic Syndrome;Previously Treated Myelody ...	Biological: Anti-Thymocyte Globulin;Drug: Cyclosporine;Biological: Filgrastim;Drug: Methylprednisolo ...	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	Recruiting	N/A	N/A	All	100	Phase 2	United States

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