Air ( DrugBank: - )

3 diseases

ID	Disease name (Link within this page)	Number of trials
85	Idiopathic interstitial pneumonia	6
97	Ulcerative colitis	3
193	Prader-Willi syndrome	1

85. Idiopathic interstitial pneumonia

Clinical trials : 627 / Drugs : 443 - (DrugBank : 120) / Drug target genes : 99 - Drug target pathways : 212

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05052229 (ClinicalTrials.gov)	April 21, 2022	2/9/2021	Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).	Pulmonary Gas Exchange and Neuro-sensory Abnormalities in Patients With Idiopathic Pulmonary Fibrosis and Mild Mechanical Restriction. Implications for Dyspnea and Exercise Intolerance	Idiopathic Pulmonary Fibrosis	Drug: Nitric Oxide;Drug: Medical air	Queen's University	Boehringer Ingelheim	Recruiting	40 Years	N/A	All	40	Early Phase 1	Canada
2	NCT03688334 (ClinicalTrials.gov)	June 1, 2018	20/9/2018	Acute Effects of Oxygen Supplementation Among IPF Patients	Acute Effects of Oxygen Supplementation During Exercise Among Patients With Idiopathic Pulmonary Fibrosis Without Resting Hypoxemia	Idiopathic Pulmonary Fibrosis	Drug: Oxygen 40 %;Drug: Medical air (sham O2)	George Papanicolaou Hospital	NULL	Unknown status	18 Years	80 Years	All	15	N/A	Greece
3	JPRN-UMIN000015508	2015/01/01	24/10/2014	A prospective randomized, multicenter trial evaluating the efficacy and safety of combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis.	A prospective randomized, multicenter trial evaluating the efficacy and safety of combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis. - Combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis.	Idiopathic pulmonary fibrosis	Using Micro Air nebulizers and vibration mesh technology (NE-U07, Omron, Tokyo, Japan), patients receiving NAC combined with pirfenidone were treated twice daily with 352.4 mg of inhaled NAC, which was diluted with saline to a total volume of 6 mL for 48 weeks. Pirfenidone 1200-1800mg (control group)	Grant for Research on Diffuse Lung Disease from the Ministry of Health, Labour and Welfare of Japan.	NULL	Complete: follow-up complete	40years-old	Not applicable	Male and Female	150	Not selected	Japan
4	JPRN-UMIN000005098	2011/02/01	18/02/2011	A randomized trial of ambulatory oxygen in patients with idiopathic pulmonary fibrosis and desaturation but without resting hypoxemia	A randomized trial of ambulatory oxygen in patients with idiopathic pulmonary fibrosis and desaturation but without resting hypoxemia - ambulatory oxygen in patients with IPF and desaturation but without resting hypoxemia	idiopathic pulmonary fibrosis	ambulatory oxygen ambulatory air	Department of Respiratory Medicine and Allergology, Kinki University School of Medicine	NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	20	Not selected	Japan
5	JPRN-UMIN000016045	2009/10/03	26/12/2014	A case-control study evaluating the efficacy and safety of combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis.	A case-control study evaluating the efficacy and safety of combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis. - Combined therapy with pirfenidone and inhaled N-acetylcysteine for idiopathic pulmonary fibrosis.	Idiopathic pulmonary fibrosis	Using Micro Air nebulizers and vibration mesh technology (NE-U07, Omron, Tokyo, Japan), patients receiving NAC combined with pirfenidone were treated twice daily with 352.4 mg of inhaled NAC, which was diluted with saline to a total volume of 6 mL for 48 weeks. Pirfenidone 1200-1800mg (control group)	Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo	,NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	20	Not selected	Japan
6	JPRN-UMIN000025256	2009/01/01	13/12/2016	Benefits of supplemental oxygen on exercise capacity and dyspnea in IPF patients	Benefits of supplemental oxygen on exercise capacity and dyspnea in IPF patients - Benefits of supplemental oxygen on exercise capacity and dyspnea in IPF patients	idiopathic pulmonary fibrosis	oxygen gas air gas	Tosei General Hospital	NULL	Complete: follow-up complete	Not applicable	75years-old	Male and Female	106	Not applicable	Japan

97. Ulcerative colitis

Clinical trials : 2,630 / Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR2200055616	2018-06-01	2022-01-14	Air insufflation colonoscopy versus water-assisted colonoscopy in patients with ulcerative colitis	Feasibility and effectiveness of water-assisted colonoscopy in patients with ulcerative colitis	ulcerative colitis	experimental group 2: water immersion colonoscopy;experimental group 2:water exchange colonoscopy;control group:Air insufflation colonoscopy ;	The Second Affiliated Hospital of Xi'an Jiaotong University	NULL	Recruiting	23	67	Both	experimental group 2:70;experimental group 2:70;control group:70;		China
2	JPRN-UMIN000018801	2015/08/27	27/08/2015	Efficasy of colonosocopy using carbon dioxide insufflation for the patients with ulcerative colitis	Efficasy of colonosocopy using carbon dioxide insufflation for the patients with ulcerative colitis - Efficasy of colonosocopy using carbon dioxide insufflation for the patients with ulcerative colitis	ulcerative colitis	Colonosocopy using carbon dioxide insufflation Colonosocopy using air insufflation	Osaka University, Graduate School of Medicine,Department of Gastroenterology and Hepatology	NULL	Recruiting	16years-old	Not applicable	Male and Female	250	Not selected	Japan
3	NCT01790061 (ClinicalTrials.gov)	November 2012	9/2/2013	Standardized Fecal Microbiota Transplantation for Ulcerative Colitis	Efficacy, Durability and Safety of Standardized Fecal Microbiota Transplantation in Patients With Moderate to Severe Ulcerative Colitis	Bacteria;Microbiota;Fecal Microbiota Transplantation;Inflammatory Bowel Disease;Ulcerative Colitis	Procedure: Standardized FMT;Drug: Traditional treatments	The Second Hospital of Nanjing Medical University	Air Force Military Medical University, China	Recruiting	6 Years	80 Years	All	500	Phase 2/Phase 3	China

193. Prader-Willi syndrome

Clinical trials : 113 / Drugs : 111 - (DrugBank : 26) / Drug target genes : 48 - Drug target pathways : 102

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03031626 (ClinicalTrials.gov)	September 1, 2016	20/1/2017	Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome	Comparison of Therapeutic Oxygen Versus Medical Air for the Treatment of Central Sleep Apnea in Infants and Children With Prader Willi Syndrome: A Proof of Concept Study	Sleep Apnea, Central;Prader-Willi Syndrome	Biological: Medical Air vs Oxygen	The Hospital for Sick Children	NULL	Recruiting	N/A	2 Years	All	10	Phase 4	Canada