Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 4 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 5 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FGFR1 [1] FGFR1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 6 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FYN [3] FYN, SRC, YES1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 7 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FYN [3] FYN, SRC, YES1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 8 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 9 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 10 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 11 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 12 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 13 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 14 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 15 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 16 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 17 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 18 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 19 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 20 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 21 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 22 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 23 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 24 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 25 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 26 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 27 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 28 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 29 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 30 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 31 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 32 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 33 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 34 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 35 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 36 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 37 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 38 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 39 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 40 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 41 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 42 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 43 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 44 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 45 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 46 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 47 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 48 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 49 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 50 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 51 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 52 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 53 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 54 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 55 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 56 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 57 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 58 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 59 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 60 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 61 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 62 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 63 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 64 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 65 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 66 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 67 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 68 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 69 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 70 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 71 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 72 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 73 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 74 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 75 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 76 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 77 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 78 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 79 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 80 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 81 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 82 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 83 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 84 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 85 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 86 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
CCN2 [1] CCN2 💬
|
Pamrevlumab Pamrevlumab 💬
| Pamrevlumab | 085 [2] 85, 113 💬
|
| 87 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 88 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 89 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 90 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 91 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 92 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 93 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 94 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 95 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 96 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 97 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 98 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 99 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 100 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 101 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 102 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 103 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 104 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 105 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [4] ABL1, EPHA2, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 106 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [4] ABL1, EPHA2, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 107 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 108 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 109 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 110 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
| 111 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
| 112 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 113 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 114 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 115 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 116 | Basal cell carcinoma 💬 1 gene, 2 drugs (DrugBank) and 1 disease |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
| 117 | Basal cell carcinoma 💬 1 gene, 2 drugs (DrugBank) and 1 disease |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
| 118 | beta-Alanine metabolism 💬 4 genes, 3 drugs (DrugBank) and 17 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 119 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 120 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
FGFR3 [1] FGFR3 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 121 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 122 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 123 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 124 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FGFR1 [2] FGFR1, FLT4 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 125 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 126 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 127 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 128 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 129 | Butanoate metabolism 💬 4 genes, 2 drugs (DrugBank) and 16 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 130 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 131 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 132 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 133 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 134 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 135 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 136 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 137 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 138 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 139 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 140 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 141 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 142 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 143 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 144 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Montelukast Montelukast 💬
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬
|
| 145 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Tipelukast Tipelukast 💬
| Tipelukast | 085 [1] 85 💬
|
| 146 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 147 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 148 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 149 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 150 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 151 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 152 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
| 153 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 154 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 155 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 156 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 157 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 158 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TACR1 [1] TACR1 💬
|
Orvepitant Orvepitant 💬
| Orvepitant | 085 [1] 85 💬
|
| 159 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
| 160 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 161 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 162 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 163 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 164 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 165 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 166 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 167 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 168 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 169 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 170 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
| 171 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD274 [1] CD274 💬
|
Atezolizumab Atezolizumab 💬
| Atezolizumab | 085 [1] 85 💬
|
| 172 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD274 [1] CD274 💬
|
Durvalumab Durvalumab 💬
| Durvalumab | 085 [1] 85 💬
|
| 173 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
PDCD1 [1] PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
| 174 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 175 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 176 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 177 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 178 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A [2] IL1A, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 179 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 180 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 181 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 182 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 183 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 184 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 185 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 186 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 187 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 188 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 189 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 190 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 191 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 192 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 193 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 194 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 195 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 196 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 197 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
| 198 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
| 199 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 200 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 201 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 202 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 203 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 204 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 205 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 206 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 207 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 208 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 209 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 210 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 211 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 212 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 213 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 214 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 215 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 216 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 217 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
| 218 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
| 219 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 220 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 221 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 222 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
| 223 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
| 224 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 225 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 [1] CCL2 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 226 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 227 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 228 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 229 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 230 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 231 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 232 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 233 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 234 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 235 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 236 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 237 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 238 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 239 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 240 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 241 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 242 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 243 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
| 244 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
| 245 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 246 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 247 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 248 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 249 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 250 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 251 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 252 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 253 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 254 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 255 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 256 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 257 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 258 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 259 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 260 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 261 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 262 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 263 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 264 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 265 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 266 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 267 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 268 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 269 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 270 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 271 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [2] IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 272 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 273 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 274 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 275 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 276 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 277 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 278 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 279 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 280 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 281 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 282 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 283 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 284 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 285 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 286 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 287 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 288 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
| 289 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 290 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
FGFR2 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 291 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 292 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 293 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 294 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 295 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 296 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 297 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 298 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
| 299 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
| 300 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 301 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 302 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 303 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
FGFR2 [3] FGFR2, FGFR3, PDGFRA 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 304 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 305 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 306 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 307 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 308 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 309 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 310 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 311 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 312 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 313 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 314 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 315 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 316 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 317 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 318 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
| 319 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 [1] OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
| 320 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 321 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 322 | Ether lipid metabolism 💬 1 gene, 1 drug (DrugBank) and 2 diseases |
ENPP2 [1] ENPP2 💬
|
Ziritaxestat Ziritaxestat 💬
| Ziritaxestat | 051 [2] 51, 85 💬
|
| 323 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 324 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 325 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 326 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 327 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 328 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 329 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 330 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 331 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 332 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 333 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 [4] CCL2, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 334 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 335 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 336 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 337 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 338 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 339 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 340 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 341 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 342 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 343 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 344 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FYN [3] FYN, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 345 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FYN [3] FYN, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 346 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 347 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 348 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 349 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 350 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 351 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 352 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 353 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 354 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 355 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 356 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 357 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 358 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 359 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 360 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 361 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
| 362 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
| 363 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
| 364 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
FGFR2 [1] FGFR2 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 365 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 366 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 367 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 368 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 369 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 370 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 371 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 372 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 373 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 374 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 375 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 376 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 377 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
| 378 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 379 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 380 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 381 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 382 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 383 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 384 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 385 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 386 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 387 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 388 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
| 389 | Hedgehog signaling pathway 💬 2 genes, 3 drugs (DrugBank) and 2 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
| 390 | Hedgehog signaling pathway 💬 2 genes, 3 drugs (DrugBank) and 2 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
| 391 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 392 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 393 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 394 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 395 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 396 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 397 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 [1] MS4A1 💬
|
Rituximab Rituximab 💬
| Rituximab | 011 [48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
|
| 398 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 399 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 400 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 401 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 402 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 403 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 404 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 405 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 406 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 407 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 408 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 409 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 410 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 411 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 412 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 413 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 414 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 415 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 416 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 417 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 418 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 419 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 420 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 421 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 422 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 423 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 424 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 425 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 426 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 427 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 428 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 429 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 430 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 431 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 432 | Hippo signaling pathway 💬 5 genes, 3 drugs (DrugBank) and 6 diseases |
CCN2 [1] CCN2 💬
|
Pamrevlumab Pamrevlumab 💬
| Pamrevlumab | 085 [2] 85, 113 💬
|
| 433 | Hippo signaling pathway 💬 5 genes, 3 drugs (DrugBank) and 6 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 434 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 435 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 436 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 437 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 438 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 439 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 440 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 441 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 442 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 443 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 444 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 445 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 446 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 447 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 448 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 449 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 450 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 451 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 452 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 453 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 454 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 455 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 456 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 457 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 458 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 459 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 460 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 461 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 462 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 463 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 464 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 465 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 466 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 467 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 468 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 469 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 470 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 471 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 472 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 473 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 474 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 475 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 476 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 477 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 478 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 479 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 480 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 481 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 482 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 483 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 484 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 485 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 486 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 487 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 488 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 489 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 490 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 491 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 492 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 493 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 494 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 495 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 496 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 497 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 498 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 499 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 500 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 501 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 502 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 503 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 504 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 505 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 506 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 507 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 508 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 509 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 510 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 [2] IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 511 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 512 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 513 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 514 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 515 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 516 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 517 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 518 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 519 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 520 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 521 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 522 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL10 [2] IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 523 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 524 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 525 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 526 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 527 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 528 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 529 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 530 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 531 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IFNGR1 [1] IFNGR1 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 532 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 533 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 534 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 535 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 536 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 537 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 538 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 539 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 540 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 541 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 542 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 543 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 544 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 545 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 546 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL10 [4] IL10, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 547 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 548 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 549 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 550 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 551 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 552 | Leukocyte transendothelial migration 💬 13 genes, 14 drugs (DrugBank) and 30 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 553 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 554 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 555 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 556 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 557 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 558 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 559 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 560 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 561 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 562 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 563 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 564 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 565 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 566 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 567 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 568 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 569 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 570 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 571 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 572 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 573 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 574 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 575 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 576 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 577 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 578 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 579 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 580 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 581 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 582 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 583 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 584 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 585 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 586 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 587 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 588 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A [3] IL1A, IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 589 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 590 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 591 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 592 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 593 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 594 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 595 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 596 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 597 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 598 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 599 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 600 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 601 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 602 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
| 603 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
| 604 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ENPP2 [1] ENPP2 💬
|
Ziritaxestat Ziritaxestat 💬
| Ziritaxestat | 051 [2] 51, 85 💬
|
| 605 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 606 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 607 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 608 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
| 609 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
| 610 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 611 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 612 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 613 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 614 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
FGFR3 [3] FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 615 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 616 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
TGFB2 [1] TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 617 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 618 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
| 619 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
| 620 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 621 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 622 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
| 623 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
| 624 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 625 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 626 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 627 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 628 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 629 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 630 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 631 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 632 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 633 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 634 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 635 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 636 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 637 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 638 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 639 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 640 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 641 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 642 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 643 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 644 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 645 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 646 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 647 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 648 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 649 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 650 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Montelukast Montelukast 💬
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬
|
| 651 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Tipelukast Tipelukast 💬
| Tipelukast | 085 [1] 85 💬
|
| 652 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 653 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 654 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 655 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 656 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 657 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 658 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 659 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Beclomethasone dipropionate Beclomethasone dipropionate 💬
| Beclomethasone dipropionate | 085 [3] 85, 97, 98 💬
|
| 660 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Methylprednisolone Methylprednisolone 💬
| Methylprednisolone | 002 [46] 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
|
| 661 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisolone Prednisolone 💬
| Prednisolone | 003 [42] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
|
| 662 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisone Prednisone 💬
| Prednisone | 002 [45] 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
|
| 663 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
| 664 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
| 665 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
| 666 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
| 667 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
| 668 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
| 669 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TACR1 [1] TACR1 💬
|
Orvepitant Orvepitant 💬
| Orvepitant | 085 [1] 85 💬
|
| 670 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
| 671 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 672 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 673 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 674 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
| 675 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 676 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 677 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 678 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 679 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 680 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 681 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 682 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 683 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 684 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 685 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 686 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 687 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 688 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 689 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 690 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 691 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 692 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 693 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 694 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 695 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 696 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 697 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 698 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 699 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
| 700 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 701 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
| 702 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
| 703 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 704 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 705 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 706 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 707 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 708 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 709 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 710 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 711 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TGFB1 [2] TGFB1, TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 712 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 713 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 714 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 715 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 716 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 717 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Lansoprazole Lansoprazole 💬
| Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬
|
| 718 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
| 719 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 720 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 721 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 722 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 723 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 724 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 725 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 726 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 727 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 728 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
FGFR1 [1] FGFR1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 729 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
| 730 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
| 731 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 732 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 733 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [3] ABL1, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 734 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [3] ABL1, FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 735 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 736 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 737 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 738 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 739 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 740 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 741 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 742 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 743 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 744 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 745 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 746 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 747 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 748 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
| 749 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
| 750 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 751 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 752 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 753 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 754 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 755 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 756 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 757 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGFR1 [6] FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 758 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 759 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 760 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 761 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 762 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 763 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 764 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 765 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 766 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
| 767 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
| 768 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 769 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 770 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 771 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 772 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 773 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 774 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 775 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 776 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 777 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 778 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 779 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 780 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD274 [1] CD274 💬
|
Atezolizumab Atezolizumab 💬
| Atezolizumab | 085 [1] 85 💬
|
| 781 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
CD274 [1] CD274 💬
|
Durvalumab Durvalumab 💬
| Durvalumab | 085 [1] 85 💬
|
| 782 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 783 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 784 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 785 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 786 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PDCD1 [1] PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
| 787 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 788 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 789 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 790 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 791 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 792 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 793 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 794 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 795 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 796 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 797 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 798 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FYN [3] FYN, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 799 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
FYN [3] FYN, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 800 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 801 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 802 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 803 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
| 804 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 805 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 806 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 807 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 808 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 809 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 810 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 811 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 812 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 813 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 814 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
FYN [2] FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 815 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
FYN [2] FYN, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 816 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
P2RY12 [1] P2RY12 💬
|
Ticagrelor Ticagrelor 💬
| Ticagrelor | 036 [3] 36, 46, 85 💬
|
| 817 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬
|
Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
| 818 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
| 819 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 820 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
| 821 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
TOP2A [2] TOP2A, TOP2B 💬
|
Etoposide Etoposide 💬
| Etoposide | 011 [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
|
| 822 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 823 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 824 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 825 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 826 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 827 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 828 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 829 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 830 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 831 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 832 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 833 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 834 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 835 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 836 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 837 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 838 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬
|
Nandrolone Nandrolone 💬
| Nandrolone | 060 [2] 60, 85 💬
|
| 839 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬
|
Nandrolone decanoate Nandrolone decanoate 💬
| Nandrolone decanoate | 060 [2] 60, 85 💬
|
| 840 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
FGFR1 [4] FGFR1, FGFR2, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 841 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 842 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 843 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 844 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRB [1] PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 845 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [2] FGFR1, KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 846 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 847 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 848 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
| 849 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
| 850 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 851 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 852 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TGFB1 [2] TGFB1, TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 853 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 854 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 855 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 856 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 857 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 858 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 859 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
| 860 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
| 861 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
| 862 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
| 863 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 864 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
| 865 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
| 866 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EPHA2 [4] EPHA2, KIT, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 867 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EPHA2 [4] EPHA2, KIT, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 868 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 869 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 870 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [2] KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 871 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 872 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [4] ABL1, EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 873 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [4] ABL1, EPHA2, KIT, PDGFRB 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 874 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 875 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 876 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 877 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 878 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
| 879 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
| 880 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 881 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [1] PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 882 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 883 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB [2] PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 884 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 885 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 886 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 887 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 888 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 889 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 890 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 891 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 892 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 893 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 894 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 895 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 896 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 897 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 898 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 899 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 900 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 901 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 902 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 903 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 904 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 905 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 906 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 907 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 908 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 909 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
FLT1 [1] FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 910 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 911 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 912 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 913 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 914 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 915 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 916 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 917 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 918 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 919 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 920 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 921 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
| 922 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
| 923 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
| 924 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 925 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 926 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 927 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 928 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 929 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 930 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Paclitaxel Paclitaxel 💬
| Paclitaxel | 046 [2] 46, 85 💬
|
| 931 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 932 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Paroxetine Paroxetine 💬
| Paroxetine | 006 [4] 6 , 13, 46, 85 💬
|
| 933 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 934 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 935 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 936 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 937 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 938 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 939 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 940 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 941 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 942 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 943 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 944 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
FYN [1] FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 945 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
| 946 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 947 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 948 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 949 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 950 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 951 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 952 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 953 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 954 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
IL10 [1] IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 955 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Paroxetine Paroxetine 💬
| Paroxetine | 006 [4] 6 , 13, 46, 85 💬
|
| 956 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
| 957 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
| 958 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 959 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 960 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 961 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 962 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 963 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 964 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 965 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 966 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PDCD1 [1] PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
| 967 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 968 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 969 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 970 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 971 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 972 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 973 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
| 974 | Taurine and hypotaurine metabolism 💬 2 genes, 1 drug (DrugBank) and 14 diseases |
GAD1 [2] GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 975 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 976 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 977 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 978 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 979 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 980 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 981 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 982 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL13 [1] IL13 💬
|
Lebrikizumab Lebrikizumab 💬
| Lebrikizumab | 085 [1] 85 💬
|
| 983 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL13 [1] IL13 💬
|
Tralokinumab Tralokinumab 💬
| Tralokinumab | 085 [2] 85, 97 💬
|
| 984 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 985 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 986 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 987 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 988 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 989 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B [2] IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 990 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 991 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 992 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 993 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 994 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 995 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 996 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 997 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
FGFR1 [1] FGFR1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 998 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 999 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 1000 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1001 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1002 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 1003 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1004 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1005 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1006 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1007 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1008 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1009 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1010 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B [3] IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1011 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1012 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1013 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1014 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1015 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
ALOX5 [1] ALOX5 💬
|
Zileuton Zileuton 💬
| Zileuton | 085 [3] 85, 160, 164 💬
|
| 1016 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 1017 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL10 [2] IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1018 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 1019 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1020 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1021 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1022 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1023 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
| 1024 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 1025 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1026 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 [1] IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1027 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
| 1028 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1029 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1030 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1031 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1032 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1033 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1034 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
| 1035 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1036 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1037 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1038 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
| 1039 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬
|
Dihydrotachysterol Dihydrotachysterol 💬
| Dihydrotachysterol | 006 [2] 6 , 85 💬
|
| 1040 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
GAD1 [2] GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 1041 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1042 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1043 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1044 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1045 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1046 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1G [1] CACNA1G 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 1047 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 1048 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1049 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1050 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1051 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1052 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1053 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
| 1054 | Valine, leucine and isoleucine degradation 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
| 1055 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
| 1056 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
| 1057 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 1058 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 1059 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
| 1060 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR [1] PTGIR 💬
|
Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
| 1061 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
| 1062 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 1063 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
| 1064 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1065 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1066 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1067 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1068 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
| 1069 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1070 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1071 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 1072 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [2] ABL1, FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1073 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [2] ABL1, FYN 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1074 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CCL2 [4] CCL2, IL10, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1075 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1076 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1077 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1078 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 1079 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1080 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 1081 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 1082 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 1083 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
| 1084 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
LCK [2] LCK, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1085 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
LCK [2] LCK, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
| 1086 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
| 1087 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 1088 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 1089 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|