ACT-385781A (Actelion Epoprostenol) ( DrugBank: Epoprostenol )

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1 disease

ID	Disease name (Link within this page)	Number of trials
86	Pulmonary arterial hypertension	2

86. Pulmonary arterial hypertension

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Clinical trials : 1,205 /  Drugs : 684 - (DrugBank : 124) / Drug target genes : 100 - Drug target pathways : 193

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01105117 (ClinicalTrials.gov)	May 2010	15/4/2010	Epoprostenol for Injection in Pulmonary Arterial Hypertension - Extension of AC-066A401	An Open-label Extension of Study AC-066A401 Investigating the Safety and Tolerability of ACT-385781A Compared to Flolan® in Injectable Prostanoid Treatment-naïve Patients With Pulmonary Arterial Hypertension (PAH)	Pulmonary Arterial Hypertension	Drug: ACT-385781A (Actelion Epoprostenol);Drug: Flolan®	Actelion	NULL	Completed	18 Years	65 Years	All	2	Phase 4	United States
2	NCT01105091 (ClinicalTrials.gov)	March 2010	15/4/2010	Epoprostenol for Injection in Pulmonary Arterial Hypertension	A Phase IV, Open-label, Randomized, Multicenter Study of the Safety, Tolerability,and Pharmacokinetics of ACT- 385781A Compared to Flolan® in Injectable Prostanoid Treatment-naïve Patients With Pulmonary Arterial Hypertension (PAH)	Pulmonary Arterial Hypertension	Drug: ACT-385781A (Actelion Epoprostenol);Drug: Flolan®	Actelion	NULL	Completed	18 Years	65 Years	All	30	Phase 4	United States