Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[4] BRAF, FLT3, KIT, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
2	Acute myeloid leukemia 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3	Acute myeloid leukemia 💬	[1] KIT 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
4	Acute myeloid leukemia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96 ...
5	Adherens junction 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[2] 51, 86 💬
6	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96 ...
7	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ...
8	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[4] 57, 86, 113, 210 💬
9	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[4] 58, 67, 86, 113 💬
10	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D03879 💬	Dobutamine	[4] 57, 58, 86, 215 💬

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