Ciliary neurotrophic factor ( DrugBank: Ciliary neurotrophic factor )


1 disease
IDDisease name (Link within this page)Number of trials
90Retinitis pigmentosa4

90. Retinitis pigmentosa


Clinical trials : 147 Drugs : 176 - (DrugBank : 43) / Drug target genes : 49 - Drug target pathways : 110
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PhaseCountries
1NCT01530659
(ClinicalTrials.gov)
January 201219/1/2012Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis PigmentosaPhotoreceptor Structure in A Phase 2 Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants With Retinitis Pigmentosa Using Rates of Change in Cone Spacing and DensityRetinitis Pigmentosa;Usher Syndrome Type 2;Usher Syndrome Type 3Drug: NT-501;Procedure: ShamNeurotech PharmaceuticalsUniversity of California, San FranciscoCompleted18 Years55 YearsAll22Phase 2United States
2NCT00447993
(ClinicalTrials.gov)
January 20079/3/2007A Study of Encapsulated Cell Technology (ECT) Implant for Patients With Late Stage Retinitis PigmentosaA Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants With Retinitis Pigmentosa Using Visual Acuity as the Primary OutcomeRetinitis PigmentosaDrug: NT-501Neurotech PharmaceuticalsNULLCompleted18 Years68 YearsBoth65Phase 2United States
3NCT00447980
(ClinicalTrials.gov)
January 20079/3/2007A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis PigmentosaA Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants With Retinitis Pigmentosa Using Visual Field Sensitivity as the Primary OutcomeRetinitis PigmentosaDrug: NT-501Neurotech PharmaceuticalsNULLCompleted18 Years64 YearsBoth68Phase 2United States
4NCT00063765
(ClinicalTrials.gov)
June 20033/7/2003Evaluation of Safety of Ciliary Neurotrophic Factor Implants in the EyeA Phase I Study of NT-501-10 and NT-501-6A.02, Implants of Encapsulated Human NTC-210 Cells Releasing Ciliary Neurotrophic Factor (CNTF), in Patients With Retinitis PigmentosaRetinitis PigmentosaDrug: Ciliary Neurotrophic Factor Implant NT-501National Eye Institute (NEI)NULLCompletedN/AN/ABoth10Phase 1United States