DDrare: Database of Drug Development for Rare Diseases

291. ヒルシュスプルング病（全結腸型又は小腸型）
［臨床試験数：13，薬物数：32（DrugBank：15），標的遺伝子数：0，標的パスウェイ数：0］

Searched query = "Hirschsprung disease, entire colon type", "Hirschsprung disease, small intestine type", "Hirschsprung disease", "Hirschprung disease", "Hirschsprung disease associated entercolitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Behavioral: anal dilation; Behavioral: colonic lavage; Behavioral: conservative treatment; Bifico; Butyrate; Butyrate enemas + routine management; Cefazolin; Citric acid; Device: SPY imaging; Erythromycin; Gold; High dose lactulose; Indocyanine Green; Indocyanine green; Kanamycin; Lactulose; Magnesium; Magnesium oxide; Metronidazole; Oral probiotic; Other: Nil per os; Other: routine management; Paraffin Oil; Paraffin oil; Picosulfate; Probiotics; Procedure: surgery treatment; Racol; Senna; Sodium Picosulfate, Magnesium Oxide and Citric Acid; Supplement nutritional supporting; VSL#3

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR2000035860	2020-10-01	2020-08-18	Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung disease	Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung disease	Hirschsprung disease	Gold Standard:The speciemens and sections will be reveiwed by three senior pediatric gastroenterology pathologists under the novel pathological grading system of ganglion cells in Hirschsprung disease, and the results is regarded as the gold standard.;Index test:Artificial intelligence assisted whole-section patholgic diagnosis system;	Xinhua Hospital, Shanghai Jiaotong University School of Medicine	NULL	Pending	0	16	Both	Target condition:138;Difficult condition:138		China

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

ChiCTR2000035860

2020-10-01

2020-08-18

Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung disease

Hirschsprung disease

Gold Standard:The speciemens and sections will be reveiwed by three senior pediatric gastroenterology pathologists under the novel pathological grading system of ganglion cells in Hirschsprung disease, and the results is regarded as the gold standard.;Index test:Artificial intelligence assisted whole-section patholgic diagnosis system;

Xinhua Hospital, Shanghai Jiaotong University School of Medicine

NULL

Pending

Both

Target condition:138;Difficult condition:138

China