DDrare: Database of Drug Development for Rare Diseases

299. 嚢胞性線維症
［臨床試験数：1,592，薬物数：1,539（DrugBank：255），標的遺伝子数：81，標的パスウェイ数：162］
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
Drug = 0.12% saline; 0.9% Isotonic Saline (IS); 0.9% Isotonic Saline (IS), 4mL; 0.9% normal saline (control); 0.9% w/v sodium chloride solution; 033841; 1,5 (Butylimino)-1,5-dideoxy-D-glucitol; 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-3-quinoline carboxylic acid; 100 mg ELX /50 mg TEZ /75 mg IVA FDC; 100 mg ELX/50 mg TEZ /75 mg IVA FDC; 100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination; 100 mg TEZ/150 mg IVA FDC; 100 mg VX-445/50 mg TEZ /75 mg IVA FDC; 100 mg/m2 dose; 100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC; 100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC; 100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC; 100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC; 100-mg VX-445 /50-mg TEZ/75-mg; 100-mg VX-445/50-mg TEZ/75-mg IVA FDC; 100mg VX-445/50mg TEZ /75mg IVA FDC; 150-mg IVACAFTOR; 150mg IVACAFTOR; 2% Chlorhexidine solution wipes; 2,3-dihydroxybutanedioic acid; 2-aminoethanethiol; 200 mg/m2 dose; 25-Hydroxyvitamin D3; 2622U90 Duramycin; 291844; 4% chlorhexidine gluconate liquid skin cleanser; 4-phenylbutyrate; 4.2% NaCl/Inhalation solution; 4.2% NaCl/inhalation solution; 5-methyltetrahydrofolate and vitamin B12; 50 mg ELX/25 mg TEZ/37.5 mg IVA fixed dose combination; 5000 IU of cholecalciferol; 552-02; 6% Hypertonic Saline (HS), 4mL; 7% Hypertonic Saline (HS); 7% NaCl; 7% saline; A-F-A-F (NovoRapid-FIASP-NovoRapid-FIASP); AAC Hexal; ABBV-2222; ABBV-3067; ABELCET; ACC; ACC600Tabs; ACETYLCYSTEINE; ACETYLCYSTEINE SODIUM; AER002; AIR DNase; AIR DNase™; ALTU-135; ALTUS-135; ALX-009; AMIKACIN SULFATE; AMILASA; AMITRIPTYLINE; AMOXICILLIN; AMYLASE; ANAKINRA; AP; AP-PA02; API; ARD-3150; ARIKACE™; ARO-ENaC; ATORVASTATIN; AZD1236; AZD5634; AZD5634 for infusion; AZD5634 for inhalation; AZD7986; AZD9668; AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; AZLI; AZLI 75 mg three times a day (TID); AZLI 75 mg three times daily (TID); AZLI 75 mg two times a day (BID)/ three times a day (TID); AZLI 75 mg two times a day (BID)/three times a day (TID); AZTREONAM; AZTREONAM LYSINE; Abelcet; Acebilustat; Acetate; Acetylcysteine; Active Treatment Group 7% Hypertonic Saline; Actrapid 100 IU/ml, Solution for injection in a vial; Actrapid Penfill 100UI/ml; Acute Antioxidant; Adempas; Adempas 0.125 mg; Adempas 0.5 mg; Adempas 1.0 mg; Adempas 2.0 mg; Adeno-associated virus-CFTR vector; Advagraf prolonged-release hard capsules; AeroVanc; Aeroquin; Aerosolized, human, plasma-derived Alpha-1 Antitrypsin; Aerosoltherapy; Air; Ajulemic acid; Alanine; Albuterol; Albuterol inhaler.; Alendronate; Alendronate sodium; Alginate; Alginate oligosaccharide; Allo-hMSCs; Alpha-1 HC 100 mg; Alpha-1 HC 200 mg; Alpha1-Proteinase Inhibitor (Human); Alpha1-proteinase Inhibitor; Amikacin; Amikacin Sulfate; Amikacin nebulization; Amikacin sulfate; Amikacina; Amikacina liposomal (Arikace?); Amikacine; Amikacine nebulization; Amikin, amiklin, amicacin, BB-K8, Biklin, Fabianol, Kaminax, Mikavir, Novamin, Pierami; Amikin®, amiklin, amicacin, BB-K8, Biklin®, Fabianol®, Kaminax, Mikavir, Novamin®, Pierami; Amiloride; Amiloride HCl; Amiloride Solution for Inhalation; Amitriptylin; Amitriptylin-CT; Amitriptylin-ct Tabletten; Amitriptyline; Amoxicillin; Amoxicillin and Clavulanic acid; Amphotericin; Amphotericin B; Amylase; Anakinra; Andecaliximab; Anti-pseudomonas IgY gargle; Anti-reflux pharmacotherapy; Antibiotic; Antioxidant Cocktail; AquADEK; AquADEKs-2; Arginine; Aridol; Aridol or Osmohale; Arikayce; Arikayce™; Arikayce™ 140 mg; Arikayce™ 560 mg; Arikayce™ 70 mg; Ataluren; Ataluren (PTC124®); Atorvastatin; Augmentin; Aurexis; Aurexis® (tefibazumab); Avian polyclonal IgY antibody against PA; Avibactam; Azithromycin; Azithromycin 250 mg tablets; Azithromycin 500 mg film-coated tablet; Aztreonam; Aztreonam Lysine for Inhalation; Aztreonam for Inhalation (AI); Aztreonam for Inhalation Solution; Aztreonam for Inhalation Solution (AZLI); Aztreonam lysine; Aztreonam lysine for inhalation; Aztreonam solución para inhalación; Aztreonan lysine; BAL; BAY 85-8501; BAY q 3939; BAY63-2521; BAY85-8501; BAYQ3939; BAYq3939; BH4; BH4 20mg; BH4 5mg; BI 1265162; BI 1265162 10 µg; BI 1265162 100 µg; BI 1265162 25 µg; BI 1265162 50 µg; BI 1323495; BI 443651; BIIL 283 BS (Amelubent); BIIL 284 BS, high dose; BIIL 284 BS, high dose, adult patients; BIIL 284 BS, high dose, pediatric patients; BIIL 284 BS, low dose; BIIL 284 BS, low dose, adult patients; BIIL 284 BS, low dose, pediatric patients; BIIL 284 BS, medium dose, adult patients; BIIL 284 BS, medium dose, pediatric patients; BLF; BRAMITOB*NEBUL 28F 300MG/4ML; BRAMITOB*NEBUL 56F 300MG/4ML; Bactrim; Balance; Behavioral: Aerobic exercise; Behavioral: Balance exercise; Behavioral: Environmental Decontamination; Behavioral: Exercise; Behavioral: Flexibility and postural exercise; Behavioral: Resistance exercise; Behavioral: Unsupervised exercise; Beta-Adrenergic cocktail; Bethkis; Biaxin ( clarithromycin); Biklin; Bio-25 probiotic; Bisphosphonate treatment; Blood sample; Blood test; Boost VHC; Boots High Strength Garlic Odour Controlled; Bramitob; Bramitob 300mg/4ml Nebuliser Solution; Bramitob® administered by PARI LC® PLUS nebulizer; Bramitob® administered by PARI eFlow® rapid electronic nebulizer; Brensocatib; Brensocatib 10 mg; Brensocatib 25 mg; Broccoli; Broccoli sprouts; Bronchitol; Bucelipase alfa; Budesonide; Budesonide-formoterol single inhaler; Burlulipase; CAYSTON aztreonam 75 mg powder and solvent for nebuliser solution; CB-280; CEFALEXIN; CEFTAZIDIME; CEFTAZIDIME PENTAHYDRATE; CEFUROXIME; CF patients with a G551D mutation and treated with Ivacaftor; CFTR Modulators; CFTR potentiator; CHF 6333; CHF6333 (Part 1 - SAD); CHF6333 (Part 2 - MAD); CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE; CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATE; CIPROXIN*6CPR RIV 500MG; CLARITHROMYCIN; CLAVULANIC ACID; CLINDAMYCIN; CLORURO SODICO 7%; COLIMICINA - 1000000 U/4 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO INTRAMUSCOLARE1 FLACONCINO POLVERE + 1 FIALA SOLVENTE 4 ML; COLIMYCINE inhalation; COLIMYCINE injectable; COLISTIMETATO SODICO; COLISTIMETHATE; COLISTIMETHATE SODIUM; COLISTIMETHATE SODIUM (A COMPONENT); COLISTIN; COLISTIN MESILATE SODIUM; COLISTINEB 2MUI; CPX; CR002; CR002 Liquid API; CRC3357, ZK-355322, Leukoton; CREON; CREON 10000 Capsules; CREON IR; CREON N 25000; CSL787; CTX-4430; CURCUMIN; CYC202; CYCLO[L-ALANYL-L-SERYL-L-ISOLEUCYL-L-PROLYL-L-PROLYL-L-GLUTAMINYL-L-LYSYL-L-TYROSYL-D-PROLYL-L-PROLYL-(2S)-2-AMINODECANOYL-L-ALPHA-GLUTAMYL-L-THREONYL]; Calcium; Calcium carbonate; Calfactant; Carbonate; Cavosonstat; Cayston; Cayston 75 mg Pulver und Lösungsmittel zur Herstellung einer Lösung für einen Vernebler; Cayston Aztreonam 75 mg powder and solvent for nebuliser solution; Cefalexin; Cefepime; Ceftaroline; Ceftazidim; Ceftazidim Fresenius Kabi; Ceftazidim Fresenius Kabi 2000 mg poeder voor oplossing voor injectie of infusie; Ceftazidime; Ceftazidime and tobramycin; Ceftazidime/avibactam; Ceftolozane; Ceftolozane/Tazobactam; Cefuroxim; Cefuroxime; Cephalexin; Cftr Modulators; Chlorhexidine; Chlorhexidine Gluconate; Chlorhexidine gluconate oral rinse; Chloride; Cholecalciferol; Cholecalciferol (Vitamin D3); Cholecalciferol (vitaminD3); Choline; Choline Chloride; Choline supplementation; Chronic Antioxidant; Cipro (Ciprofloxacin, BAYQ3939); Cipro Inhale; Ciprofloxacin; Ciprofloxacin (BAYQ3939) dry powder for inhalation; Ciprofloxacin (Cipro Inhale, BAYQ3939); Ciprofloxacin (Cipro, BAYQ3939); Ciprofloxacin (ciproxin); Ciprofloxacin DPI; Ciprofloxacin DPI (BAYQ3939); Ciprofloxacin Hydrochloride; Ciprofloxacin Inhale; Ciprofloxacin dispersion for inhalation; Ciprofloxacin for Inhalation; Ciprofloxacin hydrochloride; Ciproxin; Ciproxin Suspension; Clarithromycin; Claritromycin; Claritromycin 500mg film coated tablets; Clavulanate; Clavulanic acid; Clindamycin; Cobamamide; Colimicina; Colimycine; Colistimethat-Natrium; Colistimethate; Colistimethate 75 mg inhaled two times daily; Colistimethate Sodium; Colistimethate sodium; Colistimethate sodium (BAN, USAN), Colistimethatum natricum, Colistin sodium methanesulfonate; Colistimethate sodium (promixin); Colistin; Colistin CF; Colistin Forest - Trockenstechampullen mit Lösungsmittel; Colistineb; Colobreathe; Colomycin; Compound 1a; Continuous infusion Cefepime; Continuous infusion Ceftazidime; Continuous infusion Meropenem; Continuous infusion Piperacillin tazobactam; Continuous infusion Ticarcillin-clavulanate; Control; Control Group 0.9% Isotonic Saline; Control multivitamin; Creon 10.000, hårde enterokapsler; Creon 10000; Creon 25.000, hårde enterokapsler; Creon 25000; Creon 40.000, hårde enterokapsler; Creon IR; Creon N; Creon®; Creon® (DR/GR); Creon® 25,000; Crestor; Curcuma Longa; Curcuma Longa Extract; Curcuma Longa Extract cpl formaat 00 23,2 x 8,5 mm 723 mg; Curcumin; Cystagon; Cystagon (cysteamine bitartrate) immediate-release capsules; Cysteamine; Cysteamine bitartrate; Cysteamine bitartrate (Cystagon); Cystic Fibrosis Ready to Use Supplemental Food; D-a-tocopheryl PEG 1000 succinate; D-glucitol; D6-25-hydroxyvitamin D3; DCI; DCI 1020; DEPELESTAT; DEUTIVACAFTOR; DHA; DICLOXACILLIN; DORIBAX; DORIPENEM HYDRATE; DORNASE ALFA; DOXYCYCLINE; DP Mannitol; DTPA; DURAMYCIN; DX-890; Decolonization; Denosumab; Denufosol; Denufosol Tetrasodium (INS37217) Inhalation Solution; Denufosol tetrasodium (INS37217); Denufosol tetrasodium (INS37217) Inhalation Solution; Denufosol tetrasodium Inhalation Solution; Depelestat; Desoxyribonuclease; Detemir; Detoxifying agents for antineoplastic treatment; Deuterated Ivacaftor; Deutivacaftor; Device: 129Xe Small and Large Human Lung Coil; Device: 3He Human Lung Coil; Device: Continuous Glucose Monitoring; Device: Continuous glucose monitor (CGM); Device: Frequently Sampled Oral Glucose Tolerance Test and CGM; Device: HFNT during exercise; Device: High flow nasal oxygen cannula; Device: Home Oral Glucose Tolerance Test kit; Device: Insulin Pump; Device: Lung Clearance Index; Device: Macroduct sweat stimulator; Device: Magnetic Resonance Imaging; Device: Manuka honey sinus rinse; Device: Nocturnal oxygen , nocturnal bi-level positive pressure ventilation; Device: Non invasive ventilation; Device: Noninvasive ventilation; Device: Oxygen; Device: PARI eFlow nebulizer system; Device: PFP and SF6 Human Lung Coil; Device: Perform three multiple breath nitrogen washout tests (N2-MBW-test); Device: Positive expiratory pressure; Device: RELiZORB (immobilized lipase) cartridge; Device: SmartPill Motility System & PillCam Patency Capsule; Device: Sperti Del Sol Lamp; Device: Standard oxygen therapy/RA; Device: Standard sinus rinse; Device: Tobi Podhaler; Device: activated smart device; Device: de-activated smart device; Dexamethasone; Dexamethasone sodium phosphate 250 mg/10 ml solution; Diagnostic Test: Candy Glucose Tolerance Test; Diagnostic Test: Continuous glucose monitoring; Diagnostic Test: Dexa scan; Diagnostic Test: Infant PFT; Diagnostic Test: Injected abdominal CT; Diagnostic Test: Iontophoresis sessions in forearm of subjects with pilocarpine; Diagnostic Test: Lung Clearance Index; Diagnostic Test: Measurement of Sweat Chloride and Sweat Bromide; Diagnostic Test: Nasal brushing; Diagnostic Test: Oral glucose tolerance test; Diagnostic Test: Passive tidal breathing; Dicloxacillin; Diet; Digitoxin; Docosahexaenoic acid; Docosahexaenoic acid (DHA); Docosahexaenoic acid administration: 50 mg/kg/day during 12 months; Docosahexanoic Acid Supplement; Doribax; Doripenem; Dornase alfa; Dornase alfa (Pulmozyme); Dornase alfa [Pulmozyme®]; Dornase alpha; Doxycyclin; Doxycycline; Dry powder tobramycin; Duramycin; Duramycin, 2622U90; ECGC; EGCG; EGCG + Tocotrienol; ELEXACAFTOR; ELX; ELX (VX-445)/TEZ (VX-661)/IVA (VX-770); ELX-02; ELX/TEZ/IVA; EMEA/H/C/000125; EPI-hNE4 DX-890; EU Orphan Designation Number EU/3/02/120; EUR-1008; EUR-1008 (APT-1008); EUR-1008 25,000 Units; EZ-2053; EZ-2053 5mg/kg; Ebselen; Elexacaftor; Elexacaftor-tezacaftor-ivacaftor exposure; Engineerd Protein Inhibitor of human Neutrophil Elastase; Engineered Protein Inhibitor of human Neutrophil Elastase; Ensure High Protein; Ensure plus; Ergocalciferol; Ergocalciferol (vitamin D2); Esomeprazole; Essential amino acid intake + Leucine vs total AA supplement; Estradiol; Estradiol 2 mg; Ethambutol; Ethinyl estradiol; F-A-F-A (FIASP-NovoRapid-FIASP-NovoRapid); FDL169; FDL176; FDL176 & FDL169 coadministration; FLUCLOXACILLIN; FLUCLOXACILLIN SODIUM; FORLAX 4 g, poudre pour solution buvable en sachet; FTI, AZLI; FUSIDIC ACID; Fenretinide; Ferinject; Ferric carboxymaltose; Ferrous sulfate 325mg; Finely ground flaxseed powder; Fish oil; Flaxseed; FluMist; Flucloxacillin; Flucloxacillin 250mg/5ml Sugar-Free Powder for Oral Solution; Flucloxicillin; Flumist®; Fluticasone; Formoterol; Fortum; Fucidin; Fucidin Tablets; Fusidic acid; Fusidin; G1117337; G914167; G957389; GENISTEIN; GIP; GLP-1; GLPG1837; GLPG1837 dose 1; GLPG1837 dose 2; GLPG1837 dose 3; GLPG2222; GLPG2222 100 mg; GLPG2222 150 mg q.d.; GLPG2222 200 mg; GLPG2222 300 mg q.d.; GLPG2222 400 mg; GLPG2222 50 mg; GLPG2451 dose regimen A; GLPG2451 dose regimen B; GLPG2737; GLPG2737 single dose; GLPG3067; GLPG3067 single dose; GLUTATHIONE; GLUTATHIONE SODIUM; GS-5737; GS-5745; GS-9411; GSH; GSH (Glutathione); Galicaftor; Gallium nitrate; Garlic; Genetic: Blood or Saliva Sample Collection; Genistein; Genistein (Unconjugated Isoflavones 100); Genisteine Plus 150 mg cpl formaat 1 18,7 x 6,4 mm 438 mg; Gentamicin; Gernebcin; Gernebcin 80 mg; Ghrelin; Giving DHA-rich supplement; Glargine; Glargine insulin; Glucose; Glutamine; Glutathione; Glycine; Glycine Buffer; Gold; Growth Hormone; Growth hormone; HEPARIN SODIUM; HMSCs; HP 129Xe; HP 3He; HYPERTONIC SALINE; Helium; Helium-3; Heparin; Heparin 25mg inhalation powder, hard capsule; Heracillin; High dose of budesonide; High-Dose Vitamin D3; Honey; Human recombinant growth hormone; Hyaluronan; Hydrocortisone; Hydroxychloroquine; Hyperglycemic Clamp with concurrent GIP infusion; Hyperglycemic clamp; Hyperglycemic clamp with concurrent GLP-1 infusion; Hyperpolarized Helium-3; Hyperpolarized Helium-3 MRI of the chest; Hyperpolarized Xe129; Hyperpolarized Xenon; Hyperpolarized Xenon 129; Hyperpolarized Xenon gas; Hyperpolarized xenon-129; Hypertonic Saline; Hypertonic Saline 7%; Hypertonic bicarbonate; Hypertonic saline; Hypertonic saline (7 %) and isotonic saline (0.9%); Hypertonic saline (7%); Hypertonic saline 6% -; Hypertonic saline 7%; Hypertonic saline solution; ICS+LABA; IDPM; IDPM: Inhaled Dry Powder Mannitol; IGE025; INCRELEX*SC 1FL 4ML 10MG/ML; INDUSIL*OS GTT FL 30MG+FL 15ML; INOmax; INOmax 400ppm mol/mol inhalation gas; INS1007; INS1007 10 mg oral tablet; INS1007 25 mg oral tablet; IONIS-ENaCRx; ISOTONIC SALINE; ITRACONAZOLE; IV amikacin; IV ceftazidime; IV meropenem; IV piperacillin-tazobactam; IV ticarcillin-clavulanate; IV tobramycin; IV vancomycin hydrochloride; IVA; IVACAFTOR; Ibuprofen; Icenticaftor; IgY; Impact; Impact-Nutridrink; Increlex; Indium; Indium-DTPA; Influenza vaccination; Inhaled 7% hypertonic saline (HS); Inhaled AR-501; Inhaled Dry Powder Mannitol; Inhaled Mannitol; Inhaled Reduced Glutathione; Inhaled SNSP113; Inhaled Sodium Pyruvate; Inhaled Vancomycin; Inhaled dry powder mannitol; Inhaled hypertonic saline (7%); Inhaled mannitol; Inhaled tobramycin; Initiation of CFTR Modulator; Inomax; Insulin; Insulin Asparte; Insulin detemir; Insulin detemir [rDNA origin] injection; Insulin glargine; Insuline humaine recombinante; Interferon Gamma; Interferon gamma-1b; Intermittent, short infusion Cefepime; Intermittent, short infusion Ceftazidime; Intermittent, short infusion Meropenem; Intermittent, short infusion Piperacillin tazobactam; Intermittent, short infusion Ticarcillin-clavulanate; Inulin; Isotonic Saline; Isotonic saline; Isotonic saline 0.9%; Itraconazole; Itraconazole/voriconazole; Ivacaftor; Ivacaftor (proposed INN); Ivacaftor 125mg tablet; Ivacaftor 150 mg; Ivacaftor 150 mg or 250 mg; Ivacaftor 25 mg/75 mg; Ivacaftor 75 mg; Ivacaftor 75 mg/150 mg; Ivacaftor Exposed; Ivacaftor or elexacaftor/tezacaftor/ivacaftor; Ivacaftor+lumacaftor; Ivacaftor/Ataluren; Ivacaftor/Kalydeco; J01GB01; JBT-101; JBT-101 (lenabasum); KB001; KB001-A; KREON 25000; KREON N 25000; KREON de Liberación Inmediata; Kalydeco; Kalydeco 150 mg film-c; Kalydeco 150 mg film-coated tablets; Kalydeco 150mg; Kineret; Klacid; Kreon 25 000; Kreon 25,000 Units; Kreon 25000; Kreon® 25,000; L-Glutamine; L-Lysine; L-Lysine N acetylcysteinate; L-Lysine N-acetylcysteinate; L-Lysine- N-acetylcysteinate; L-Lysine-N-acetyl-L-cysteinate; L-Lysine-N-acetylcysteinate; L-alanine; L-arginine; LABA/LAMA; LANTUS*SC 5CAR3ML100UI/ML; LAU-7b; LENABASUM; LEVOFLOXACIN HEMIHYDRATE; LINEZOLID; LIPASA; LIPASE; LIPASE LIP2; LU 70274; LUM; LUM/IVA; LUM/IVA fixed-dose combination; LUMACAFTOR; Lactic acid; Lactic acid producing organisms; Lactizole nebulization; Lactobacillus reuteri; Lactobacillus rhamnosus; Lactobacillus rhamnosus GG; Lansoprazole; Lantus 100 units/ml solution for injection in a cartridge; Lantus® 100 Units/ml solution for injection in a vial. Lantus® 100 Units/ml solution for injection in a cartridge. Lantus® 100 Units/ml solution for injection in a pre-filled pen; Lenabasum; Lenabasum 20 mg; Lenabasum 5 mg; Leucine; Levemir; Levemir 100 U/ml solution for injection in a cartridge, Levemir 100 U/ml solution for injection in a pre-filled pen; Levemir FlexPen; Levemir Penfill; Levemir insulin; Levofloxacin; Levofloxacin Kabi; Levofloxacin hemihydrate; Linez; Linezolid; Linoleic acid; Linoleic acid supplementation; Lipase CLEC; Lipase Lip2 from Yarrowia lipolytica; Lipitor; Liposomal Amikacin; Liposomal Amikacin (Arikace TM); Liposomal Amikacin (Arikace™); Liposomal amikacin for inhalation; Liposomal amikacin for inhalation (Arikayce™) using the PARI Investigational eFlow® Nebulizer.; Liposomal amphotericin B (Ambisome®); Liprotamasa; Liprotamase; Liprotamase Powder for Oral Solution; Loestrin (norethindrone acetate and ethinyl estradiol); Lonodelestat; Losartan; Lubiprostone; Lucinactant; Lucinactant first; Lumacaftor; Lumacaftor / ivacaftor; Lumacaftor Plus Ivacaftor Combination; Lumacaftor plus Ivacaftor; Lumacaftor, Ivacaftor Drug Combination; Lumacaftor-Ivacaftor treatment; Lumacaftor-ivacaftor; Lumacaftor/Ivacaftor; Lumacaftor/ivacaftor; Lumacaftor/ivacaftor 100mg/125mg tablets; Lumacaftor/ivacaftor 200mg/125mg; Lumacaftor/ivacaftor 200mg/125mg tablets; Lumacaftor/ivacaftor 200mg/83mg tablet; Lym-X-Sorb powder; Lysine; Lysomucil 10 %; MAG-DHA; MANNITOL; MECASERMIN; MEROPENEM; MEROPENEM TRIHYDRATE; MINOCYCLINE HYDROCHLORIDE; MMF; MOLI 1901; MONITOR; MP-376; MP-376 (Levofloxacin Solution for Inhalation); MP-376 (Levofloxacin solution for Inhalation); MRI with PFP; MRT5005; MS1819; MS1819-SD; MSI-1995; MTT; Macrogol; Macrogol 4000; Mannite; Mannitol; Mannitol + pulmozyme; Mannitol inhalation powder; Matched isoglycemic clamp; Mecasermin; Medical Grade Oxygen; Melphalan; Menadiol Diphosphate; Menadiol diphosphate; Menadiol sodium diphosphate; Meropenem; Meropenem Fresenius Kabi; Meropenem Fresenius Kabi 1 g poeder voor oplossing voor injectie of infusie; Meropenem Infusion; Mesenchymal Stem Cells; Metformin; Metformin Hydrochloride; Metformine; Metformine HCL 500 PCH; Miglustat; Minocycline; Modified Oral Glucose Tolerance Test (50g 4-hours); Modified lipid formulation; Molgramostim; Molgramostim nebulizer solution; Moli 1901; Moli 1901 (2622U90, duramycin); Moli1901; Moli1901 (2622U90, duramycin); Moxifloxacin; Moxifloxacin hydrochloride; Mucoid exopolysaccharide P. aeruginosa immune globulin IV; Mucolysin; Mucomyst; Multienzymes (lipase, protease etc.); Mupirocin; Mupirocin Intranasal Creme; N-(5-hydroxy-2,4- bis(trimethylsilyl)phenyl)-4-oxo- 1,4-dihydroquinoline-3-carboxamide; N-(5-hydroxy-2,4-bis(trimethylsilyl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide; N-(trans-3-(5-((R)-1-hydroxyethyl)-1,3,4-oxadiazol-2-yl)cyclobutyl)-3-phenylisoxazole-5-carboxamide; N-acetylcystein; N-acetylcysteine; N-acetylcysteine (NAC); N6022; N91115; NAC; NAL; NEB/01-07; NEBCINE; NO; NOXAFIL - 40 MG/ML SOSPENSIONE ORALE USO ORALE FLACONE (VETRO) 105 ML 1 FLACONE; NR; Nacystelyn; Nacystelyn®; Nasal Aztreonam; Nebcin; Nebcin (tobramycin); Nebcinal; Nebcinal Tobi; Nebulization of Amikacin during NIV (RR: 15 cycles/minute); Nebulization of Amikacin during NIV (RR: 25 cycles/minute); Nebulization tobramycin; Nexium; Nexium 20; Nitrate; Nitric Oxide; Nitric Oxide 160 ppm; Nitric Oxide for Inhalation; Nitric oxide; Nitrite; Nitrogen; None; None assigned; Norethindrone; Norgestimate; Normal Saline; Normal saline; Normal saline IV, salt tablets; Normal saline solution; Normal saline:; Norvir; Norvir 100 mg film-coated tablets; Novamin; Novo Rapid; Novo Rapid Insulin (Novonordisk); NovoNorm 0.5 mg; NovoNorm 1 mg; NovoNorm 2 mg; NovoRapid 100 U/ml, solution for injection in a vial. NovoRapid Penfill 100 U/ml, solution for injection in a cartridge. NovoRapid FlexPen 100 U/ml, solution for injection in a pre-filled pen.; NovoRapid Aspartate; Novolog insulin; Novorapid / humalog short acting insulin; Noxafil; Noxafil - oral suspension 40 mg/ml; Noxafil 100 mg; Noxafil®; Nutridrink-Impact; Nutropin AQ; Nutropin AQ [somatropin (DNA origin) injection]; OGT 918; OLIGOG CF-5/20; OMEGA-3-ACID TRIGLYCERIDES; OSCN-; Oleic Acid; Oleic acid supplementation; OligoG; OligoG (60 mg/ml); OligoG CF-5/20; OligoG CF-5/20 - 17.5 mg; OligoG CF-5/20, 17,5 mg, Hartkapsel mit Pulver zur Inhalation; OligoG CF/20 - 27.5 mg; OligoG CF/20 - 37.5 mg; OligoG CF/20, 27,5 mg, Hartkapsel mit Pulver zur Inhalation; OligoG CF/20, 37,5 mg, Hartkapsel mit Pulver zur Inhalation; OligoG DPI; OligoG Dry powder for inhalation; OligoG-CF5/20, Alginate oligosaccharide (G-block) fragment; Oligomer of Sodium Alginate; Omadacycline; Omadacycline Injection [Nuzyra]; Omadacycline Oral Tablet [Nuzyra]; Omalizumab; Omega 3; Omega 3 Premium; Omega-3; Omega-3 triglycerides; Omeprazole; Omeprazole 40mg Capsule; Once-daily insulin detemir; Oral Aztreonam; Oral Glucose Tolerance test (75g 2-hour); Oral Glutathione; Oral ciprofloxacin; Oral ciprofloxacin plus inhaled colistin; Oral reduced l-glutathione; Oral roflumilast; Orkambi; Orkambi 100 mg/125 mg film-coated tablets; Orkambi 200 mg/125 mg film-coated tablets; Orkambi: contains lumacaftor and ivacaftor; Orkambi®; Ortho-cyclen, Ethinyl estradiol/norgestimate, 0.035 mg/0.250 mg; Oseltamivir; Osmohale; Other non-sponsor pancreatic enzyme replacement therapy; Other respiratory system products; Other: A-STEP; Other: A-STEP (New Protocol); Other: Absorptive clearance scan; Other: Air - oxygen; Other: Autogenic drainage; Other: Balance; Other: Blood glucose results; Other: Comparator: CPET cycle ergometer (Gold Standard); Other: Continuation of dornase alfa (dnase); Other: Continuation of hypertonic saline (HS); Other: Diagnostics for glucose tolerance with 3 different methods.; Other: Discontinuation of dornase alfa (dnase); Other: Discontinuation of hypertonic saline (HS); Other: Exercise capacity; Other: Fruit juice; Other: Glucose -potentiated arginine (GPA) stimulation tests; Other: Glucose profile for 2 weeks; Other: Hepatic elastography; Other: High Glycemic Index Meal; Other: Hyperpolarized Xenon MRI; Other: Hypoglycemic Clamp; Other: Impact Peptide 1.5; Other: Inhalable Hypertonic saline 7%; Other: Inhalable Hypertonic saline 7% + Hyaluronan 0.1%; Other: Liquid Meal Test (Carbohydrate-rich); Other: Liquid Meal Test (Fat-rich); Other: Liquid Meal Test (Mixed); Other: Low Glycemic Index Meal; Other: Mixed Meal Tolerance Test; Other: Mixed meal test evaluation test arm; Other: Muscle oxygenation; Other: No doxycycline; Other: No pancreatic enzyme replacement therapy; Other: Non-hormonal period; Other: OGTT; Other: On-demand treatment; Other: Ophthalmologic examinations; Other: Oral Glucose Tolerance Test; Other: Oral Glucose Tolerance Test (OGTT) assessment arm; Other: Oxygen - Air; Other: Pentadecanoic acid (PA) and Triheptadecanoin (THA); Other: Reaction Time and Postural Control; Other: Sham Comparator; Other: Sputum Sample; Other: Sputum sample; Other: Stool Sample; Other: Technetium [Tc-99m] sulfur colloid and Indium [In-111] DTPA; Other: Test Soda; Other: Tobacco questionnaire; Other: Tobramycin time of administration; Other: blood sample; Other: glucose solution at a dose of 1.75 g/kg (up to a maximum of 75 g) for the OGTT and glucose solution at a dose of 0.5 g/kg (up to a maximum of 35 g) was injected in 2.5-3 min for the IGTT; Other: measure of endothelial function; Other: quercetin; Other: routine therapy; Oxygen; P-1037; PAAG15; PANCREASE MT; PANCREASLIPASE; PANCREATIN; PANCREATIN (PAncreas Powder); PANCREATIN (Pancreas Powder); PANCREATINA; PANCREATINA (Páncreas Polvo; PANCREATINA (Páncreas Polvo); PANCREAZE; PANCREAZE®; PANCRECARB® (pancrelipase); PANCRELIPASE AMYLASE; PANZYTRAT 25000; PBI4050; PC945; PEG; PERTZYE; PFP; PFT; PGM169/GL67A; PIPERACILLIN; PIPERACILLIN SODIUM; PL 0010/0211; PO azithromycin; PO ciprofloxacin; POL6014; POL7080; POSACONAZOLO; PPI treatment; PREFOLIC*30CPR GASTROR 15MG; PROMIXIN*NEBUL 30MONOD 1MUI; PROTEASA; PROTEASE; PTC-0161480; PTC-124; PTC-C124; PTC124; PTI-428; PTI-801; PTI-808; PUR118; Pancreas Powder; Pancrease; Pancrease MT 10.5, or MT 21; Pancreatin; Pancrelipase; Pancrelipase Delayed Release; Pancrelipase Delayed Release Capsule; Pancrelipase Microtablets; Pancrelipase amylase; Pancrelipase microtablets; Pancrelipase with bicarbonate; Pancrelipase/Pancreas Powder; Pankreatin; Panzytrat® 25,000; Panzytrat® ok; Perfluorinated gas/oxygen mixture; Phenylbutyrate; Phosphate; Physiologic serum nebulized nasally; Physiological solution; Pilocarpine; Pilocarpine Nitrate 5%; Pioglitazone; Piperacillin; Piperacillin sodium , tazobactam sodium; Piperacillin with Tazobactam (tazocin); Piperacillin-tazobactam combination product; Piperacillin/Tazobactam; Piperacillin/Tazobactam Kabi - Fresenius Kabi Austria; Piperacilline/Tazobactam Fresenius Kabi 2 g/0,25 g poeder voor oplossing voor infusie; Piperacilline/Tazobactam Fresenius Kabi 4 g/0,5 g poeder voor oplossing voor infusie; Plerixafor; Plerixafor mobilization of autologous CD117 stem cells; Polyethylene Glycol 3350; Polyethylene glycol; Porcine (pig) PERT; Porcine PERT; Posaconazole; Posaconazolo; Prednisolone; Prednisone; Procedure: Airway clearance technique; Procedure: Blood draw; Procedure: Blood draw.; Procedure: Blood sampling for determination of serum Zn; Procedure: Continuous Glucose Monitoring System (CGMS); Procedure: Dual Energy X-ray Absorptiometry (DEXA); Procedure: Exhaled Nitric Oxide; Procedure: FDG-PET; Procedure: Growth Hormone Stimulation Test; Procedure: HGPIV diagnosis test; Procedure: HOMAR-IR diagnosis test; Procedure: History and physical exam.; Procedure: IV glucose tolerance test; Procedure: Indirect Calorimetry; Procedure: Oral Glucose Tolerance Test; Procedure: Oral Glucose tolerance test; Procedure: Physiotherapy, exercise, percutaneous gastrostomy feeds; Procedure: Pulmonary Function Testing; Procedure: Pulmonary function testing.; Procedure: Sputum Collection; Procedure: Urinary collect; Procedure: Whole body Protein Turnover; Procedure: Whole body Protein Turnover Study; Procedure: Whole body protein turnover; Procedure: bronchoscopy with BAL; Procedure: sodium bicarbonate; Procedure: spirometry; Prograft capsules; Prolastin; Prolastin (drug); Promixin; Promixin 1 million International Units (IU) Powder for Nebuliser Solution; Promixin, 1 million International Units (IU) Powder for Nebuliser Solution; Promixin,1 millón de Unidades Internacionales,polvo para solución para inhalación por nebulizador; Promixin/Tadim; Protease; PsAer IgY; Pulmaquin®; Pulmozyme; Pulmozyme (Dornase alpha); Pulmozyme (dornase alfa); Pulmozyme single use ampule; Pulmozyme®; QAU145; QBW251; QBW276; QBW276 1500mcg; QBW276 300mcg; QBW276 Succinate; QR-010; Quercetin; R03AC02; R03CC02; R05C B01; RIFAMPICIN; RIOCIGUAT; RPL554; RPS 2505; Radiation: MRI Pancreas and Liver; Radiolabelled OligoG CF-5/20 6% Solution; Radiolabelled OligoG CF-5/20 6% Solution for Nebulisation; Radiolabelled OligoG CF-5/20 DPI; Radiolabelled OligoG CF-5/20 Dry Powder for Inhalation (DPI); Rapeglinide; Ravicti; Ravicti high dose; Ravicti low dose; Recombiant human Desoxyribonuclease ( rhDNase); Recombinant Human DNase (Pulmozyme); Recombinant human IGF-1; Recombinant humanized monoclonal antibody omalizumab to IgE; Recombinant truncated SPINT2 protease inhibitor; Red Blood Cell Zn; Reduced glutathione; Reduced glutathione sodium salt; Repaglinide; Repaglinide and Insulin; Reparixin; Resunab, ajulemic acid, anabasum; Resveratrol; RhBSSL; RhDNAse; Rifampicin; Rifampin; Rimactan; Riociguat; Riociguat (Adempas, BAY63-2521); Roflumilast; Roflumilast Oral Tablet; Roscovitine; Rosuvastatin; Rosuvastatin calcium; Roxithromycin; Répaglinide; S-1226; SALBUTAMOL; SALINE; SB-656933 Tablets; SB-656933-AAA; SB656933; SE10599; SELICICLIB; SF6; SIN ASIGNAR; SLIT Amikacin; SLIT(TM) Amikacin; SMX; SNSP113; SODIUM ALGINATE; SODIUM BICARBONATE BP; SODIUM CHLORIDE; SODIUM CHLORIDE 7%; SODIUM CHLORIDE PH. EUR.; SODIUM CHLORIDE SOLUTION 0.9%; SPI-1005 Ebselen 200mg Capsule x1; SPI-1005 Ebselen 200mg Capsule x2; SPI-1005 Ebselen 200mg Capsule x3; SPORANOX; SPX-101; STERILE PYROGEN-FREE ISOTONIC NACL SOLUTE (0.9% W / V); SUB185183; SULFAMETHOXAZOLE; Salbutamol; Saline; Saline 0.9% inhalation solution; Saline Solution; Salmeterol; Saxagliptin; Seliciclib; Serum Zn; Short-acting Insulin (Actrapid); Sildenafil; Sildenafil (Acute-1 hour); Sildenafil (Subchronic-4 weeks); Sildenafil 40mg oral capsule; Simvastatin; Simvastatin treatment for 28 days; Sitagliptin; Snack beverage; Sodium (R)-8-methyl-2-(3-methylbenzofuran-2-yl)-5-(1-(tetrahydro-2H-pyran-4-yl)ethoxy)quinoline-4-ca; Sodium 4-Phenylbutyrate; Sodium 4-Phenylbutyrate (4PBA); Sodium Bicarbonate; Sodium Chloride; Sodium Pyruvate in 0.9% Sodium Chloride Solution; Sodium alginate; Sodium bicarbonate; Sodium chloride; Sodium chloride (7%); Sodium chloride 0,9%; Sodium chloride 6%; Sodium chloride 7%; Sodium nitrite; Soluble fiber supplementation; Somalgen; Somatropin; Spiriva; Spiriva Respimat; Spiriva Respimat 2.5 mcg; Spiriva Respimat 2.5 microgram; Spiriva Respimat 2.5 microgram, solution for inhalation; Sporanox; Sporanox 10 mg/ml Oral Solution; Sputum; Ss-Adrenergic cocktail; Standard Care; Standard Formula; Standard formula (Enfamil); Standard of care IV antibiotic(s); Standardized turmeric root extract; Study medication, azithromycin; Sulfamethoxazole; Sulfate; Sulfato de amikacina; Sulfur Colloid; Sunflower Oil; Sunflower oil; Supplementation with vitamin D2/D3; Symbiotic Formula with DHA and antioxidants; Symdeko; Symkevi; Symkevi 100mg/150mg Film-coated tablets; Synrinse; T 100 PARI; T-326; T100; T100 PARI; TACROLIMUS; TAD 600; TAFLUPROST; TAZOBACTAM; TAZOBACTAM SODIUM; TBD; TBM100; TBM100C; TEZ; TEZ/IVA; TEZACAFTOR; THA; TIOTROPIUM; TIOTROPIUM BROMIDE MONOHYDRATE; TIP; TIP (Tobramycin inhalation powder); TIS (Tobramycin Inhalation Solution); TIS or TIP; TMP; TNSE; TOBI; TOBI (tobramycin); TOBI 300 mg / 5 mL nebuliser solution; TOBI 300 mg/5 ml Lösung für einen; TOBI 300 mg/5 ml Lösung für einen Vernebler; TOBI 300 mg/5 ml Nebuliser Solution; TOBI 300 mg/5 ml solución para inhalación por nebulizador; TOBI 300 mg/5 ml, solution pour inhalation par nébuliseur; TOBI 300mg/ 5ml solución para inhalación con nebulizador; TOBI 300mg/5mL Nebuliser Solution; TOBI 300mg/5mL nebuliser solution; TOBI 300mg/5ml Nebuliser solution; TOBI PODHALER; TOBI PODHALER - 28 MG POLVERE PER INALAZIONE CAPSULA RIGIDA USO INALATORIO BLISTER(ALU/ALU) 56 CAPSULE + 1 INALATORE; TOBI PODHALER*448CPS 28MG+10IN; TOBI Podhaler; TOBI Podhaler 28 mg Hartkapseln mit Pulver zur Inhalation; TOBI Podhaler 28 mg inhalációs por, kemény kapszula; TOBI*NEBUL 56F 1D 300MG/5ML; TOBI®; TOBI™ Podhaler™ 112 mg inhaled twice daily; TOBRAMICINA; TOBRAMYCIN; TOBRAMYCIN SULFATE; TR02; TRIMETHOPRIM; Tacrolimus; Tacrolimus and MMF; Tacrolimus capsules; Tacrolimus prolonged-release hard capsules; Tad; Tadim; Tafluprost; Talniflumate; Tauroursodeoxycholic acid; Tazobactam; Technetium Sulfur Colloid; Tedizolid; Tedizolid IV; Tedizolid PO; Tefibazumab; Teicoplanin; Teicoplanin Sandoz 200 mg powder and solvent for solution for injection or infusion or oral solution.; Telavancin; Telavancin Injection; Tezacaftor; Tezacaftor (TEZ); Tezacaftor/Ivacaftor; Tezacaftor/Ivacaftor + Ivacaftor; Tezacaftor/Ivacaftor 100mg/150mg; Tezacaftor/Ivacaftor/100mg/150mg; Tezacaftor/ivacaftor; Tezacaftor/ivacaftor 100mg/150mg; Tham; The gut mycobiota and microbiota profile; The lung mycobiota and microbiota profile; Theophylline; Ticarcillin; Tigerase®; Tiotropium; Tiotropium Bromide (monohydrate); Tiotropium Respimat; Tiotropium Respimat 1.25 microgram solution for inhalation; Tiotropium Respimat 1.25 microgram, solution for inhalation; Tiotropium Respimat 1.25 micrograms solution for inhalation; Tiotropium Respimat® inhaler; Tiotropium bromide; Tiotropium bromide 5 mcg; Tiotropium bromide high; Tiotropium bromide low; Tiotropium bromide medium; Tiotropium bromide monohydrate; Tiotropium bromide-low dose-2.5mcg; Tobacco; Tobi; Tobi 300 mg/5 ml Nebuliser Solution; Tobi 300mg/5ml Nebuliser solution.; Tobi 300mg/5ml Solución para inhalación por nebulizador.; Tobi Inhalant Product; Tobi Nebcinal; Tobramcyin; Tobramicina; Tobramicina polvere inalatoria; Tobramycin; Tobramycin (Gernebcin®); Tobramycin / Bramitob; Tobramycin / TOBI; Tobramycin 100 PARI; Tobramycin Inhalation Powder; Tobramycin Inhalation Powder (TIP); Tobramycin Inhalation Powder TIP delivered by the T-326 Inhaler; Tobramycin Inhalation Solution (TIS); Tobramycin Powder; Tobramycin Solution for Inhalation; Tobramycin Steri-Neb 300 mg/5 ml, inhalation solution; Tobramycin dry powder; Tobramycin for Inhalation; Tobramycin inhalation powder; Tobramycin inhalation solution; Tobramycin inhalation solution using a PARI LC® Plus nebulizer.; Tobramycin injection 40mg/1ml; Tobramycin nebulized nasally; Tobramycin solution for inhalation; Tobramycin solution for inhalation (TOBI); Tobramycin solution for inhalation 300 mg; Tobramycine; Tobramycinum; Tobrineb/Bramitob; Tocotrienol; Treatment; Treatment with polyethylene glycol (Macrogol 4000); Trifakta; Trikafta; Trimethoprim; Trimethoprim Sulfamethoxazole (TMP/SMX); Trimethoprim and Sulfamethoxazole; Trimethoprim-sulfamethoxazole; Trimethoprim/Sulfamethoxazole; Trimethoprim/Sulfamethoxazole (TMP/SMX); Trimetoprim; Triple combination therapy; Turmeric; ULTRESA; Ultrase; Ultrase® MT12; Ultrase® MT20; Unconjugated Isoflavones 100 (PTI G-4660, 87% Genistein); Uridine; Urinary levels of PIIINP as a marker of changes in renal function; Ursodiol; V-Fend; VEDROP; VFEND 40 mg/ml powder for oral suspension; VITAMIN E - TGPS; VORICONAZOLE; VR496; VRT-813077; VRT-826809; VRT-893661; VRT-893661 VRT-0893661; VX-121; VX-152; VX-371; VX-371 in hypertonic saline; VX-371 in saline; VX-440; VX-445; VX-445 / TEZ / IVA; VX-445 / TEZ / IVA FDC; VX-445 /TEZ/IVA; VX-445/TEZ/IVA; VX-561; VX-561 (CTP-656); VX-659; VX-659/ TEZ/IVA; VX-659/TEZ/IVA; VX-659/Tezacaftor/Ivacaftor; VX-661; VX-661 / VX-770; VX-661 Plus Ivacaftor Combination; VX-661 plus ivacaftor combination; VX-661, VRT-893661; VX-661/Ivacaftor; VX-661/VX-770; VX-661/VX-770 (TEZ/IVA); VX-661/ivacaftor (VX-770) 100mg/150 mg; VX-661/ivacaftor 100 mg/ 150 mg; VX-661/ivacaftor 100mg/150 mg; VX-661/ivacaftor 100mg/150mg; VX-661/ivacaftor 50 mg/ 75 mg; VX-770; VX-770, VRT-8130077; VX-770, VRT-813077; VX-809; VX-809 & VX-770; VX-809 / VX-770; VX-809, VRT-826809; VX-809/VX-770; Vaccin grippal pandémique H1N1; Vaccination with vaccine against hepatitis A and B; Valganciclovir; Valganciclovir [Valcyte]; Vancomycin; Vancomycin hydrochloride inhalation powder; Vancomycin inhalation powder; Vantobra (tobramycin); Vardenafil; Vedrop; Vfend; Vitamin B12; Vitamin D; Vitamin D Oil; Vitamin D Powder; Vitamin D2; Vitamin D3; Vitamin E; Vitamin K; Vitamin K supplementation, dose #1; Vitamin K supplementation, dose #2; Vitamin: Choline Bitartrate (2-hydroxyethyl) trimethylammonium salt 1:1; Voriconazole; WATER FOR INJECTIONS, EP; Water; Water for injections; XOLAIR; Xenon; Xenon-129; Xolair; Xolair 150 mg Pulver und Injektionslösung zur Herstellung einer Injektionslösung; Xylitol; ZENPEP; ZITHOMAX 40 mg/ml ENFANTS; ZITHROMAX; ZITHROMAX 250 mg; Zavesca; Zenpep; Zinc; Zinc acetate; Zinc acetate (20mg/d); Zithromax; Zitromax; Zn; Zoledronic acid; [N/A]; [NA]; [SPX-101]; [na]
No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2016-001440-18-NL (EUCTR)	30/05/2018	16/01/2018	The influence of cytochrome P450 3A4 inhibitors on serum levels of Ivacaftor in cystic fibrosis patients and healthy subjects.	Pharmacokinetic interactions between ivacaftor and cytochrome P450 3A4 inhibitors in cystic fibrosis patients and healthy controls - IACI	cystic fibrosis and healthy subjects;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]	Trade Name: Ivacaftor Trade Name: claritromycin 500mg film coated tablets Product Name: Claritromycin Trade Name: Azithromycin 500 mg film-coated tablet Product Name: azithromycin Trade Name: Norvir 100 mg film-coated tablets Product Name: Norvir	university medical center utrecht	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	12	Phase 4	Netherlands
No.
TrialID
Date_
enrollment
Date_
registration
Public_title
Scientific_title
Condition
Intervention
Primary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
Phase
Countries
EUCTR2016-001440-18-NL
(EUCTR)
30/05/2018
16/01/2018
The influence of cytochrome P450 3A4 inhibitors on serum levels of Ivacaftor in cystic fibrosis patients and healthy subjects.
Pharmacokinetic interactions between ivacaftor and cytochrome P450 3A4 inhibitors in cystic fibrosis patients and healthy controls - IACI
cystic fibrosis and healthy subjects;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Trade Name: Ivacaftor
Trade Name: claritromycin 500mg film coated tablets
Product Name: Claritromycin
Trade Name: Azithromycin 500 mg film-coated tablet
Product Name: azithromycin
Trade Name: Norvir 100 mg film-coated tablets
Product Name: Norvir
university medical center utrecht
NULL
Authorised-recruitment may be ongoing or finished
Female: yes
Male: yes
Phase 4
Netherlands